Results 71 to 80 of about 39,911 (165)

Bioconjugates of PAMAM dendrimers with trans-retinal, pyridoxal, and pyridoxal phosphate

, 2012
A Filipowicz, S WołowiecDepartment of Cosmetology, University of Information Technology and Management in Rzeszów, Rzeszów, PolandBackground: Bioconjugates of a polyamidoamine (PAMAM) G3 dendrimer and an aldehyde were synthesized as
Filipowicz A, Wołowiec S
core  

Alliinase: A Comprehensive Review of the Pivotal Enzyme in Garlic Chemistry and Its Applications

Food Frontiers, Volume 7, Issue 4, July 2026.
Garlic crude extract was purified to obtain alliinase, which catalyzes alliin hydrolysis to release allicin. The free and immobilized alliinase shows potential applications in food, biotechnology, pharmaceuticals, health products, and biosensors. ABSTRACT Alliinase is a pyridoxal 5′‐phosphate (PLP)‐dependent lyase that serves as the cornerstone of the ...
Zhenlin Han, Tian Ye, Yantian Tang, Guodong Su, Jiazhou Li, Ningyang Li   +5 more
wiley   +1 more source

Hydration of the pyridoxal-5'-phosphate. An electrochemical study

, 2017
The determination of the kinetic and equilibrium constants of the hydration of pyridoxal-5’-phosphate (PLP) was carried out by a voltammetric study. Application to the dissociation of the hydroxyl group in ortho with the formyl group is considered and a ...
T Pineda, F García-Blanco, M Domínguez, M Blázquez, R Izquierdo   +4 more
core   +1 more source

Vitamin‐Responsive Disorders: From Molecular Basis to Clinical Presentation and Therapy

Journal of Inherited Metabolic Disease, Volume 49, Issue 4, July 2026.
ABSTRACT Vitamin‐dependent cofactors are essential for numerous metabolic reactions, and defects affecting their uptake, conversion, utilisation, or regeneration constitute a heterogeneous group of inherited metabolic disorders (IMDs). Although dietary vitamin intake is sufficient to sustain coenzyme synthesis in healthy individuals, it is insufficient
Cécile Acquaviva, Yann Nadjar, Manuel Schiff, Christine Vianey‐Saban, Alain Fouilhoux, Jean‐François Benoist   +5 more
wiley   +1 more source

Racemisation of Amino Acids: From Synthetic Challenge to Biological Significance

ChemBioChem, Volume 27, Issue 11, 15 June 2026.
Racemisation, once considered an undesirable synthetic side reaction, also occurs naturally in amino acids and influences biological processes. Evidence links stereochemical conversion to ageing, protein turnover, and cellular development. This review examines mechanisms, control strategies in synthesis, applications and implications in physiology ...
Othman Al Musaimi
wiley   +1 more source

Rational Design of Salmonella typhi Acid Phosphatase for Efficient Production of Pyridoxal 5′-Phosphate

Pyridoxal 5′-phosphate (PLP) is highly valuable in food and medicine. However, achieving the efficient biosynthesis of PLP remains challenging. Here, a salvage pathway using acid phosphatase from Salmonella typhi (StAPase) and pyridoxine oxidase from ...
Jing Wang (6206297), Wei Song (30780), Xin Xu (11989), Jian Wen (286688), Guipeng Hu (11524903), Wanqing Wei (7358411), Xiaomin Li (207257), Cong Gao (276817), Xiulai Chen (107463), Jing Wu (54032), Liming Liu (107470)   +10 more
core   +1 more source

Inhibition of gp120-CD4 interaction and human immunodeficiency virus type 1 infection in vitro by pyridoxal 5'-phosphate

, 1994
Pyridoxal 5'-phosphate and related compounds were tested for their ability to inhibit gp120-CD4 interaction and human immunodeficiency virus infection in vitro.
Schopfer, L M, Heinzinger, N K, Salhany, J M, Guo, L, Stevenson, M   +4 more
core   +1 more source

Pyridoxal 5′-Phosphate Is a Slow Tight Binding Inhibitor of E. coli Pyridoxal Kinase

, 2012
Pyridoxal 5′-phosphate (PLP) is a cofactor for dozens of B6 requiring enzymes. PLP reacts with apo-B6 enzymes by forming an aldimine linkage with the ε-amino group of an active site lysine residue, thus yielding the catalytically active holo-B6 enzyme ...
Verne Schirch, Martino L di Salvo, Martin K Safo, Gandhi, Amit, Schirch, Verne, Parroni, Alessia, Desai, Jigar V., Martin K. Safo, Isabel N González, Mohini S. Ghatge, Roberto Contestabile, Amit K Gandhi, Safo, Martin A., Isabel Nogués González, Camara, Christina M., Jigar V Desai, Christina M Camara, Rita Florio, Ghatge, Mohini S., Alessia Parroni, Florio, Rita, Contestabile, Roberto, di Salvo, Martino L., Mohini S Ghatge, Jigar Desai, Gonzalez, Isabel N., DI SALVO, Martino Luigi   +26 more
core   +1 more source

Comparing the sensitivity of pyridoxal-5-phosphate, homocysteine and neopterin in coronary heart disease

, 2002
Blood serum pyridoxal-5-phosphate, homocysteine and neopterin concentrations have been examined in 30 healthy individuals and 87 patients with coronary heart disease, verified by coronary angiography.
Rudzite Vera, Fuchs Dietmar, Trusinskis Karlis, Jurika Edite, Erglis Andrejs, Kalnins Uldis, Jegere Sanda, Frick Barbara   +7 more
core   +1 more source

Cars2‐Mediated Cysteine Catabolism Drives Brown Fat Development and Thermogenesis Through Persulfidating EBF2

Advanced Science, Volume 13, Issue 31, 4 June 2026.
We demonstrate that Cars2, a cysteine catabolic enzyme in mouse iBAT, is critical for cold tolerance and brown adipocyte differentiation. Through its CPERS activity, Cars2 produces CysSSH/H2S to induce EBF2 persulfidation, promoting its interaction with PPARγ and BRG1 to enhance thermogenic gene expression.
Xin Peng, Hongyong Song, Yin Long, Kaimin Wu, Yinkun Fu, Wenkai Zhou, Wenyan Li, Zhe Shi, Xu‐Yun Zhao   +8 more
wiley   +1 more source