Results 81 to 90 of about 39,911 (165)
, 1992 To gain more information about the kinetics of vitamin B-6 metabolism in vivo, the metabolism of tracer was examined after the simultaneous intravenous administration of [32P] and [14C]pyridoxal phosphate and [3H]pyridoxal in two 93-kg pigs and two 60-kg
Douglas W. Townsend +9 more
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Bulletin of the Korean Chemical Society, Volume 47, Issue 6, Page 745-755, June 2026.Vitamins could regulate both MMP‐2 and MMP‐9 expression and activity through transcriptional and MAPK signaling pathway modulation. This study highlights the potential of vitamins as low‐toxicity therapeutic or adjunct agents for targeting MMP‐mediated cancer progression. Abstract Matrix metalloproteinases (MMP‐2 and MMP‐9) are key regulators of cancer
Yen Thi Nguyen +5 more
wiley +1 more source
Effect of pyridoxal phosphate on the DNA binding site of activated hepatic glucocorticoid receptor [PDF]
, 1978 The binding of rat liver glucocorticoid.receptor complexes to DNA-cellulose and nuclei has been studied after activation of the complexes by heating. Subsequent exposure to pyridoxal 5'-phosphate or pyridoxal markedly inhibited this binding.
Litwack, G., Cake, M.H., Di Sorbo, D.M.
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Aspartame Increases the Risk of Pancreatic Ductal Adenocarcinoma
eFood, Volume 7, Issue 3, June 2026.Aspartame (APM) is a widely used artificial sweetener associated with various health concerns, including potential links to diabetes, cardiovascular diseases, and an increased risk of cancer. A comprehensive approach incorporating data mining, machine learning, network toxicology, molecular docking, molecular dynamics simulations, and clinical sample ...
Jumin Xie +5 more
wiley +1 more source
The role of pyridoxal-5'-phosphate with simple sugars on caridovascular diseases prediction in rats
, 2007 The objective of the present study is to assess the effect of different dietary simple sugars (sucrose, glucose and fructose) on the prediction of cardiovascular disease (CVD) risk factors, with regard to supplementation with high dose of vitamin B6 (500
W H Abo-Elnour +3 more
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General Psychiatry, Volume 39, Issue 3, June 2026.ABSTRACT Background Nutraceutical supplementation targeting mitochondrial function has been proposed as a beneficial therapeutic strategy to improve physical and mental health in psychiatric patients. Aims To summarise the results of studies evaluating nutraceutical supplementation targeting mitochondrial function in patients with psychiatric disorders.
Juan Tortajada +9 more
wiley +1 more source
Journal of Applied Toxicology, Volume 46, Issue 6, Page 1987-2002, June 2026.ABSTRACT Unsymmetrical dimethylhydrazine (UDMH), a highly toxic rocket propellant with known multiorgan effects, requires urgent characterization of its chronic low‐dose toxicity. Using an integrated approach including exploratory transcriptomics (n = 3/group) and metabolomic (n = 4/group) approaches in male Sprague–Dawley rats exposed to high‐dose ...
Fuzhou Liu +6 more
wiley +1 more source
Plasma Pyridoxal 5´-Phosphate Level in Children with Intractable and Controlled Epilepsy [PDF]
Objective Intractable epilepsy is a serious neurologic problem with different etiologies. Decreased levels of pyridoxal phosphate in cerebral spinal fluid of patients with intractable epilepsy due to pyridoxine dependency epilepsy are reported.
Ghofrani, Mohammad +2 more
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Genomic and Transcriptomic Insights Into Salinity Tolerance in Dry Pea
Legume Science, Volume 8, Issue 2, June 2026.ABSTRACT Salinity is a major crop production constraint in dry pea (Pisum sativum L.), making the development of salt‐tolerant varieties essential to improve crop productivity and land‐use efficiency. The genetic mechanisms of salt tolerance in dry pea are largely unknown, and research on salt‐tolerant genes is limited.
Shailesh Raj Acharya +11 more
wiley +1 more source
Angewandte Chemie, Volume 138, Issue 22, 25 May 2026.Current interest in artificial cell research underscores its potential to deepen our understanding of life's fundamental processes. This review highlights advances in bottom‐up coacervate‐based artificial cell engineering via combined integration of cellular hallmarks.
Arjan Hazegh Nikroo +3 more
wiley +2 more sources