Results 121 to 130 of about 40,643 (298)
Transfer of Sulfur from IscS to IscU during Fe/S Cluster Assembly [PDF]
, 2001 The cysteine desulfurase enzymes NifS and IscS provide sulfur for the biosynthesis of Fe/S proteins. NifU and IscU have been proposed to serve as template or scaffold proteins in the initial Fe/S cluster assembly events, but the mechanism of sulfur ...
Hoff, Kevin G. +3 more
core +1 more source
THE INTERACTION OF PYRIDOXAL PHOSPHATE WITH ALCOHOL DEHYDROGENASE
THE JOURNAL OF VITAMINOLOGY, 1967 The interaction of PAL-P with ADH in vitro was observed, and electrophoretic mobility and absorption spectrum also changed. The molar ratios (PAL-P:ADH) of PAL-P-ADH complex was about 1:9.
Kozo Yamada +2 more
openaire +4 more sources
The FEBS Journal, EarlyView.Schlikker et al. characterized the conversion of pyridoxal to pyridoxamine under conditions mimicking the ones likely existing at the origin of metabolism. These conditions triggered nitrogen incorporation into amino acids in solution before the origins of enzymes.
Mariarita Bertoldi, Gianluca Molla
wiley +1 more source
Manual for starch gel electrophoresis: A method for the detection of genetic variation [PDF]
, 1987 The procedure to conduct horizontal starch gel electrophoresis on enzymes is described in detail. Areas covered are (I) collection and storage of specimens, (2) preparation of tissues, (3) preparation of a starch gel, (4) application of enzyme extracts ...
Aebersold, Paul B. +4 more
core
First‐in‐class inhibitors of SbnA reduce siderophore production in Staphylococcus aureus
The FEBS Journal, EarlyView.The production of the iron‐chelating compound staphyloferrin B by the most invasive S. aureus strains is crucial for colonization, virulence, and survival in the host. Staphyloferrin B biosynthesis is carried out by eight enzymes, the Sbn system, that offer an appealing source of potential targets for the development of antimicrobials.
Sarah Hijazi +15 more
wiley +1 more source
Pteridines, 1993 Incorporation of fatty acids into phospholipids has been investigated using samples of rat liver tissue homogenate, Krebs-Ringer-phosphate buffer (pH = 7.4) containing 0.3% albumin, fatty acid mixture and glyceroL The addition of L-kynurenine (4 nmol/g ...
Rudzite Vera +5 more
doaj +1 more source
The FEBS Journal, EarlyView.Cystathionine β‐synthase (CBS) is an essential enzyme involved in cysteine metabolism. The mutation R336C, associated with severe homocystinuria and of high incidence in Qatar, reduces its activity. Our research shows that this mutation does not destabilize the enzyme fold but subtly alters the tautomeric equilibrium of the PLP cofactor within the ...
Carolina Conter +10 more
wiley +1 more source
Parkinson’s Disease: Carbidopa, Nausea, and Dyskinesia [Retraction]
Clinical Pharmacology: Advances and Applications, 2021 Hinz M, Stein A, Cole T. Clin Pharmacol. 2014;6:189–194.The Editor-in-chief and Publisher of Clinical Pharmacology: Advances and Applications wish to retract the published article.This perspective article cites several original ...
Hinz M, Stein A, Cole T
doaj
A loss of Pdxk model of Parkinson disease in Drosophila can be suppressed by Buffy
BMC Research Notes, 2017 Background The identification of a DNA variant in pyridoxal kinase (Pdxk) associated with increased risk to Parkinson disease (PD) gene led us to study the inhibition of this gene in the Dopa decarboxylase (Ddc)-expressing neurons of the well-studied ...
P. Githure M’Angale, Brian E. Staveley
doaj +1 more source
Long-term follow-up of an individual with vitamin B6-dependent seizures [PDF]
, 1999 We report on a 31-year-old female with vitamin B6-dependent seizures whose seizure onset was in the neonatal period. Her elder brother had the same disorder and died in infancy. Administration of vitamin B6 was initiated in the postnatal period.
Hattori, Junri +4 more
core +1 more source