Comparative Proteomic Analysis for a Putative Pyridoxal Phosphate-Dependent Aminotransferase Required for Virulence in [PDF]
The Plant Pathology Journal, 2021 Acidovorax citrulli (Ac) is the causative agent of bacterial fruit blotch disease in watermelon. Since resistant cultivars have not yet been developed, the virulence factors/mechanisms of Ac need to be characterized. This study reports the functions of a
Jongchan Lee, Lynn Heo, Sang-Wook Han
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Proteomic and Phenotypic Analyses of a Putative YggS Family Pyridoxal Phosphate-Dependent Enzyme in Acidovorax citrulli [PDF]
The Plant Pathology Journal, 2023 Acidovorax citrulli (Ac) is a phytopathogenic bacterium that causes bacterial fruit blotch (BFB) in cucurbit crops, including watermelon. However, there are no effective methods to control this disease.
Lynn Heo +5 more
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Bioconjugates of PAMAM dendrimers with trans-retinal, pyridoxal, and pyridoxal phosphate
International Journal of Nanomedicine, 2012 Bioconjugates of a polyamidoamine (PAMAM) G3 dendrimer and an aldehyde were synthesized as carriers for vitamins A and B₆, and the bioavailability of these vitamins for skin nutrition was investigated.Nuclear magnetic resonance (NMR) and ultraviolet-visible methods were used to characterize the structure of the bioconjugates and for monitoring release ...
Stanisław Wołowiec +1 more
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Versatility of Pyridoxal Phosphate as a Coating of Iron Oxide Nanoparticles [PDF]
Nanomaterials, 2017 Pyridoxal 5′-phosphate (PLP) is the most important cofactor of vitamin B6-dependent enzymes, which catalyses a wide range of essential body functions (e.g., metabolism) that could be exploited to specifically target highly metabolic cells, such as tumour
Debora Bonvin +5 more
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Multi-Omics and Network-Based Drug Repurposing for Septic Cardiomyopathy [PDF]
PharmaceuticalsBackground/Objectives: Septic cardiomyopathy (SCM) is a severe cardiac complication of sepsis, characterized by cardiac dysfunction with limited effective treatments.
Pei-Pei Liu +8 more
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SLC25A38 is required for mitochondrial pyridoxal 5’-phosphate (PLP) accumulation [PDF]
Nature CommunicationsMany essential proteins require pyridoxal 5’-phosphate, the active form of vitamin B6, as a cofactor for their activity. These include enzymes important for amino acid metabolism, one-carbon metabolism, polyamine synthesis, erythropoiesis, and ...
Izabella A. Pena +16 more
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Conversion of pyridoxal to pyridoxamine with NH3 and H2 on nickel generates a protometabolic nitrogen shuttle under serpentinizing conditions [PDF]
The FEBS Journal, EarlyView.Recent studies show that Ni0 catalyzes amino acid synthesis from 2‐oxoacids via reductive amination. We show that the cofactor pyridoxal is reductively aminated to pyridoxamine, the NH2‐transferring intermediate of transaminations, with NH3 (~ 5 mm) and H2 (5 bar) on Ni0 catalysts within hours in water under serpentinizing hydrothermal vent conditions (
Manon Laura Schlikker +7 more
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A novel synthesis of pyridoxal-5'-phosphate.
Agricultural and Biological Chemistry, 1977 Pyridoxal-5′-phosphate was synthesized in excellent yield by phosphorylation of 1-secondaryammo-l,3-dihydro-7-hydroxy-6-methyl-furo(3,4-c)pyridine which was readily obtained by a condensation reaction between pyridoxal and a secondary amine.
Hideaki Fukawa +3 more
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CODECARBOXYLASE NOT THE 3-PHOSPHATE OF PYRIDOXAL
Journal of Biological Chemistry, 1947 I. C. Gunsalus, W. W. Umbreit
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Chemical and Pharmaceutical Bulletin, 1966 Akira Saito, Mitsuo Yamada, Zenzo Tamura
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