Modern Analytical Techniques in Epilepsy Research. [PDF]
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The vascularly perfused small intestine of the rat was utilized to study the absorption and metabolism of pyridoxamine (PM) and pyridoxamine-5'-phosphate (PMP), independent of other tissues including erythrocytes. [3H]PM or [3H]PMP was administered intralumenally with or without the addition of unlabeled PM, or PMP or inorganic phosphate.
Lavell M Henderson
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Isolation and Structural Characterization of Acrylamide−Pyridoxamine Adducts
Chemical Research in Toxicology, 2011 Pyridoxamine (PM) is an effective inhibitor of the formation of the carcinogen acrylamide (AA) from its precursors in low-moisture model systems. Although AA is widely assumed to act by scavenging carbonyl compounds, no alternative pathways have to date been explored.
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Pyridoxamine treatment ameliorates large artery stiffening and cerebral artery endothelial dysfunction in old mice [PDF]
Journal of Cerebral Blood Flow and Metabolism, 2023 Age-related increases in large artery stiffness are associated with cerebrovascular dysfunction and cognitive impairment. Pyridoxamine treatment prevents large artery stiffening with advancing age, but the effects of pyridoxamine treatment on the ...
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Effect of pyridoxamine on chemical modification of proteins by carbonyls in diabetic rats: characterization of a major product from the reaction of pyridoxamine and methylglyoxal [PDF]
Archives of Biochemistry and Biophysics, 2002 Advanced glycation end products (AGEs) from the Maillard reaction contribute to protein aging and the pathogenesis of ageand diabetes-associated complications.
Ram Nagaraj, Markus O Lederer
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