Pyridoxamine-Oxaloacetic Transaminase of Rat Kidney
H L, WU, M, MASON
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Abstract Skeletal muscle hypertrophy requires a substantial nutrient influx for biomass accretion, but global metabolite exchange during growth is poorly characterized. Therefore, we profiled the metabolite uptake and release in insulin‐like growth factor‐1 (IGF‐1)‐stimulated C2C12 myotubes and human muscle 24 h after resistance exercise ...
Tim Havers +16 more
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Enzymatic transamination of pyridoxamine. II. Crystalline pyridoxamine-pyruvate transaminase.
H, WADA, E E, SNELL
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S‐Adenosyl‐d‐Methionine as a Non‐Physiological Substrate for a Wide Range of SAM‐Dependent Enzymes
From methylation and cyclisation to radical chemistry, diverse enzyme classes utilise the non‐canonical cofactor d‐SAM. These findings reveal an unexpected tolerance of SAM‐dependent catalysis towards inversion of the methionine Cα stereocentre. The ability of SAM‐dependent enzymes to accept S‐adenosyl‐d‐methionine [d‐SAM, (SS,RCα)‐SAM] instead of the ...
Philipp Germer +17 more
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Age-Specific Ex Vivo Modulation of Gut-Brain Axis-Associated Metabolites by Galacto-Oligosaccharides and Nutrient Blends in Early Childhood. [PDF]
Ferrier L +7 more
europepmc +1 more source
A whole‐cell biocatalytic cascade in engineered Escherichia coli RARE couples the ω‐transaminase from Pseudomonas psychrotolerans with pyruvate decarboxylase from Zymomonas mobilis to shift transamination toward amine formation via pyruvate removal. Integration of the cascade into a chemo‐enzymatic synthesis pathway enables the scalable production of 2,
Laura Edit Barabás +5 more
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Metabolomic Signatures of Relapse and Survival in AML Patients Receiving Allogeneic Hematopoietic Stem Cell Transplantation. [PDF]
Novitzky-Basso I +7 more
europepmc +1 more source
Maternal B-vitamin status modifies the risk of congenital heart disease in offspring associated with prenatal persistent organic pollutants exposure. [PDF]
Li S +10 more
europepmc +1 more source
Pyridoxamine does not reduce arterial stiffness in an 8-week randomized double-blind placebo-controlled intervention trial with abdominally obese individuals. [PDF]
Van den Eynde MDG +8 more
europepmc +1 more source
Advances in Targeting the AGEs-RAGE Pathway for the Treatment of Diabetic Kidney Disease. [PDF]
Li X, Mei J.
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