Results 191 to 200 of about 9,118 (224)
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Stabilities of metal chelates of pyridoxamine
Archives of Biochemistry and Biophysics, 1957Abstract The acid dissociation constants of pyridoxamine, and the formation constants of its 1:1 and 2:1 chelates with Cu(II), Ni(II), Co(II), Fe(III), Mn(II), Zn(II), and Cd(II) ions have been determined by a potentiometric method. The structures of the metal chelate compounds formed are deduced with the aid of the titration curves, and the relative
R L, GUSTAFSON, A E, MARTELL
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Biochemistry, 2007
Pyridoxamine (PM) is a promising drug candidate for treatment of diabetic nephropathy. The therapeutic effect of PM has been demonstrated in multiple animal models of diabetes and in phase II clinical trials. However, the mechanism of PM therapeutic action is poorly understood.
Sergei V, Chetyrkin +4 more
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Pyridoxamine (PM) is a promising drug candidate for treatment of diabetic nephropathy. The therapeutic effect of PM has been demonstrated in multiple animal models of diabetes and in phase II clinical trials. However, the mechanism of PM therapeutic action is poorly understood.
Sergei V, Chetyrkin +4 more
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The Journal of Nutrition, 1979
The vascularly perfused small intestine of the rat was utilized to study the absorption and metabolism of pyridoxamine (PM) and pyridoxamine-5'-phosphate (PMP), independent of other tissues including erythrocytes. [3H]PM or [3H]PMP was administered intralumenally with or without the addition of unlabeled PM, or PMP or inorganic phosphate.
M W, Hamm, H, Mehansho, L M, Henderson
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The vascularly perfused small intestine of the rat was utilized to study the absorption and metabolism of pyridoxamine (PM) and pyridoxamine-5'-phosphate (PMP), independent of other tissues including erythrocytes. [3H]PM or [3H]PMP was administered intralumenally with or without the addition of unlabeled PM, or PMP or inorganic phosphate.
M W, Hamm, H, Mehansho, L M, Henderson
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FT-IR study of pyridoxamine 5′ phosphate
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2003Aqueous solutions of pyridoxamine 5' phosphate (PMP) at several pH conditions have been studied using FT-IR spectroscopy using the attenuated total reflection (ATR) technique. In spite of the strong intense OH stretching and bending bands of water, most of the vibrational structure of solute can be observed from 900 to 1500 cm(-1).
A, Salvà +4 more
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Enzymatic transamination of pyridoxamine in tobacco plants
Plant Science, 2013Vitamin B6 (VB6) comprises a group of pyridine compounds that are involved in a surprisingly high diversity of biochemical reactions. Humans and animals depend largely on plants for their VB6 nutrition. Many studies have focused on biosynthesis of VB6 and comparatively little is known about VB6 metabolic conversion in plants.
ShuoHao, Huang +4 more
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Unexpected isomeric equilibrium in pyridoxamine Schiff bases
Bioorganic Chemistry, 2009Pyridoxamine is a vitamin B(6) derivative involved in biological reactions such as transamination, and can also act as inhibitor in protein glycation. In both cases, it has been reported that Schiff base formation between pyridoxamine and carbonyl compounds is the main step.
Miquel, Adrover +3 more
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Fluorescence properties of pyridoxamine 5-phosphate
Biochimica et Biophysica Acta (BBA) - Biophysics including Photosynthesis, 1965Abstract 1. 1. The absorption and fluorescence spectra of pyridoxamine 5-phosphate were studied as a function of pH. From spectroscopic data the pK of the species in the singlet excited state were determined. 2. 2. The limiting polarization of fluorescence p0 = 0.41 was measured and by means of Perrin's equation the molar volume of the ...
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Current opinion in investigational drugs (London, England : 2000), 2005
BioStratum is developing pyridoxamine (Pyridorin), an advanced glycation end-product (AGE) inhibitor, for the potential prevention of diabetic nephropathy. By January 2004, phase II trials had been completed.
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BioStratum is developing pyridoxamine (Pyridorin), an advanced glycation end-product (AGE) inhibitor, for the potential prevention of diabetic nephropathy. By January 2004, phase II trials had been completed.
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1974
Publisher Summary Enzymes containing pyridoxal phosphate as their native cofactor may, in some cases, be purified through the use of agarose columns to which pyridoxamine phosphate has been covalently bound. An enzyme for which this method has been used successfully is hepatic tyrosine aminotransferase. In addition, such an agarose conjugate has been
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Publisher Summary Enzymes containing pyridoxal phosphate as their native cofactor may, in some cases, be purified through the use of agarose columns to which pyridoxamine phosphate has been covalently bound. An enzyme for which this method has been used successfully is hepatic tyrosine aminotransferase. In addition, such an agarose conjugate has been
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Bestimmung von Pyridoxamin und Pyridoxal
1967In einem Erlenmeyerkolben werden 4 ml Pyridoxaminlosung (0,01 %ig, in Aqua dest.), 30 ml Aqua dest. und 5 ml Kaliumphosphatlosung vermischt; hierzu gibt man 0,2 g festes Eisensulfat und 0,1 g festes Natriumglyoxalat und 5 ml Leberhomogenat. Nach gutem Durchmischen wird das Gefas verschlossen und 2 Stunden bei 60° C gehalten.
Heinrich Kraut, Ursula Imhoff
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