Results 71 to 80 of about 5,366 (188)

Pyridoxamine-phosphate oxidases and pyridoxamine-phosphate oxidase-related proteins catalyze the oxidation of 6-NAD(P)H to NAD(P).

, 2019
6-NADH and 6-NADPH are strong inhibitors of several dehydrogenases that may form spontaneously from NAD(P)H. They are known to be oxidized to NAD(P)+ by mammalian renalase, an FAD-linked enzyme mainly present in heart and kidney, and by related bacterial
Noël, Gaëtane, Morsomme, Pierre, Marbaix, Alexandre, Vertommen, Didier, Van Schaftingen, Emile, Bommer, Guido, Chehade, Georges   +6 more
core   +1 more source

Scavenging methylglyoxal improves bone quality and defect healing in diabetic mice

Bone Reports
Hyperglycemia in diabetes leads to the formation of methylglyoxal (MG) and accumulation of advanced glycation end-products (AGEs). We previously reported that exogenous MG exposure deteriorated osteoblastic differentiation in vitro and diabetic mice ...
Toshifumi Hikichi, Kumi Kimura, Seiichi Munesue, Yu Oshima, Ai Harashima, Tomo Hamada, Kanu Shimokawa, Yuki Fushitani, Hisanori Goto, Hiroyuki Tsuchiya, Satoru Demura, Hidenori Matsubara, Yasuhiko Yamamoto   +12 more
doaj   +1 more source

The Rotational Mobility of Pyridoxamine 5-Phosphate

Journal of Biological Chemistry, 1970
Abstract The technique of fluorescence polarization was used to study the degree of mobility of the cofactor pyridoxamine 5-phosphate bound to the catalytic site of the enzyme aspartate aminotransferase. While the cofactor of the phosphopyridoxamine form of the enzyme exhibits rotational mobility, the pyridoxyl 5-phosphate residues of the reduced ...
openaire   +2 more sources

Vitamin B6 form produced by Lactobacillus induces metabolic disorder and suppresses multi-pathogenic bacteria

Communications Biology
Vitamin B6 comprises six vitamers, pyridoxal, pyridoxine, pyridoxamine, pyridoxal 5′-phosphate (PLP), pyridoxine 5′-phosphate (PNP), and pyridoxamine 5′-phosphate (PMP), recognized for pleiotropic functions in mitigating oxidative stress and modulating ...
Ying Wu, Zhenmin Ling, Liang Peng, Xing Wang, Yue He, Aman Khan, El-Sayed Salama, Sourabh Kulshreshtha, Pu Liu, Xiangkai Li   +9 more
doaj   +1 more source

Late-onset drug-resistant epilepsy in pyridoxamine 5′-phosphate oxidase deficiency: a case report

Journal of Medical Case Reports
Background Pyridoxamine 5′-phosphate oxidase deficiency is a rare inborn error of vitamin B6 metabolism that presents with drug-resistant epileptic seizures.
Erfan Naghavi, Afshan Davari, Amir Reza Bahadori, Mohammad Razmafrooz, Hamed AmiriFard, Iman Sabzgolin, Abbas Tafakhori, Mehrdad Sheikhvatan, Sara Ranji   +8 more
doaj   +1 more source

Prevention of Arterial Stiffening by Pyridoxamine in Diabetes Is Associated with Inhibition of the Pathogenic Glycation on Aortic Collagen

, 2010
Background and purpose: Our team previously demonstrated that diabetes induces a deterioration in vascular dynamics, in parallel with the enhanced formation of advanced glycation end products.
張國柱;梁金銅;蔡佩珊;吳明修;許寬立, CHANG, KUO-CHU;LIANG, JIN-TUNG;TSAI, PEI-SHAN;WU, MING-SHIOU;HSU, KWAN-LIH   +1 more
core   +1 more source

Role of pyridoxamine in the formation of the amadori/heyns compounds and aggregates during the glycation of β-lactoglobulin with galactose and tagatose

, 2012
The effect of pyridoxamine on the Maillard reaction during the formation of conjugates of β-lactoglobulin with galactose and tagatose under controlled conditions (pH 7, 0.44 aw, 40 and 50 °C, for 6 days) has been studied, for the first time, by means of ...
Moreno, F. Javier, Villamiel, Mar, Olano, Agustín, Corzo-Martínez, Marta   +3 more
core   +1 more source

Pyridoxamine protects against mechanical defects in cardiac ageing in rats: studies on load dependence of myocardial relaxation

, 2017
Our team demonstrated in the past that pyridoxamine attenuated arterial stiffening by targeting the pathogenic formation of glycated collagen cross-links in aged rats.
吳明修;吳恩婷;王植賢;張國柱, Wang, Chih-Hsien;Wu, En-Ting;Wu, Ming-Shiou;Tsai, Ming-Shian;Ko, Ya-Hui;Chang, Ru-Wen;Chang, Chun-Yi;Chang, Kuo-Chu   +1 more
core   +1 more source

Culturing of Giardia lamblia under microaerobic conditions can impact metronidazole susceptibility by inducing increased expression of antioxidant enzymes

International Journal for Parasitology: Drugs and Drug Resistance
The microaerophilic/anaerobic protist Giardia lamblia is a world-wide occurring parasite of the human small intestine. It causes giardiasis which manifests as diarrhoea accompanied by other sequelae.
Kateryna Starynets, Ana Paunkov, Anja Wagner, Klaus Kratochwill, Christian Klotz, David Leitsch   +5 more
doaj   +1 more source

Similarity between pyridoxal/pyridoxamine phosphate-dependent enzymes involved in dideoxy and deoxyaminosugar biosynthesis and other pyridoxal phosphate enzymes.

, 1994
A multiple sequence alignment among aspartate aminotransferase, dialkylglycine decarboxylase, and serine hydroxymethyltransferase (DAS) was used for profile databank search.
BOSSA, Francesco, Stefano Pascarella, Francesco Bossa, PASCARELLA, Stefano   +3 more
core   +1 more source