Results 81 to 90 of about 4,298 (230)

Do We Need to Monitor B‐Vitamins and Homocysteine During Initiation of Foslevodopa/Foscarbidopa Therapy?

Movement Disorders, EarlyView.
Aida Shaghaghi‐Zadeh, Matthias Höllerhage, Florian Wegner, Lan Ye, Ishana Schneidereit, Tobias Hegelmaier, Rebecca Jacob, Christoph Schrader, Martin Klietz   +8 more
wiley   +1 more source

Phenotypic characterization of Arabidopsis thaliana mutants that alleviate root growth defects in a vitamin B6 biosynthesis mutant

The FEBS Journal, EarlyView.
Vitamin B6 is a critical molecule for plant metabolism and development. Rsr4‐1, a loss‐of‐function mutant in a vitamin B6 biosynthesis gene, has a distinct short root phenotype. Here we describe five novel suppressor mutants with an rsr4‐1 background that have normalized root growth and distinct phenotypic and molecular characteristics, representing a ...
Marcelina Parra, Paige Henning, Clayton Bailes, Sanja Roje, Hanjo Hellmann   +4 more
wiley   +1 more source

Scavenging methylglyoxal improves bone quality and defect healing in diabetic mice

Bone Reports
Hyperglycemia in diabetes leads to the formation of methylglyoxal (MG) and accumulation of advanced glycation end-products (AGEs). We previously reported that exogenous MG exposure deteriorated osteoblastic differentiation in vitro and diabetic mice ...
Toshifumi Hikichi, Kumi Kimura, Seiichi Munesue, Yu Oshima, Ai Harashima, Tomo Hamada, Kanu Shimokawa, Yuki Fushitani, Hisanori Goto, Hiroyuki Tsuchiya, Satoru Demura, Hidenori Matsubara, Yasuhiko Yamamoto   +12 more
doaj   +1 more source

The Rotational Mobility of Pyridoxamine 5-Phosphate

Journal of Biological Chemistry, 1970
Abstract The technique of fluorescence polarization was used to study the degree of mobility of the cofactor pyridoxamine 5-phosphate bound to the catalytic site of the enzyme aspartate aminotransferase. While the cofactor of the phosphopyridoxamine form of the enzyme exhibits rotational mobility, the pyridoxyl 5-phosphate residues of the reduced ...
openaire   +2 more sources

Vitamin B6: too much, too little, too late? An analysis of sales trends in Australia from 2023 to 2025

Internal Medicine Journal, EarlyView.
Abstract Background Peripheral neuropathy associated with vitamin B6 (pyridoxine) is dose and duration dependent. High‐dose vitamin B6 products associated with adverse neurological effects are available in Australia, prompting recent regulatory action to reschedule products containing ≥50 mg pyridoxine to schedule 3 (pharmacist only).
Wai‐Jo Jocelin Chan, Jennifer Hunter, Vivian Yeukman Lee, Rose Cairns, Slade Mathews, Joanna E. Harnett   +5 more
wiley   +1 more source

Late-onset drug-resistant epilepsy in pyridoxamine 5′-phosphate oxidase deficiency: a case report

Journal of Medical Case Reports
Background Pyridoxamine 5′-phosphate oxidase deficiency is a rare inborn error of vitamin B6 metabolism that presents with drug-resistant epileptic seizures.
Erfan Naghavi, Afshan Davari, Amir Reza Bahadori, Mohammad Razmafrooz, Hamed AmiriFard, Iman Sabzgolin, Abbas Tafakhori, Mehrdad Sheikhvatan, Sara Ranji   +8 more
doaj   +1 more source

Natural variation in the promoter of OsPDX1.2 enhances vitamin B6 accumulation and cold tolerance in rice

Journal of Integrative Plant Biology, EarlyView.
Allelic variation in the promoter of the pyridoxal phosphate synthase OsPDX1.2 caused variation in the ACE‐box cis‐elements, resulting in differing OsPDX1.2 expression due to differences in binding affinity between the OsbZIP18 transcriptipn factor and the ACE‐box, contributing to variation in vitamin B6 levels and cold tolerance among rice varieties ...
Bi Wang, Qiu Yi Wang, Wen Jie Shi, Rong Hui Li, Xu Dong Zhang, Li Ping Wang, Shi Jia Xia, Kai Xi Chen, Jun Jie Zhou, Yang Yang Sun, Jing He, Alisdair R. Fernie, Ying Chun Han, Jun Zhou Li, Yu Heng Shi, Xian Qing Liu, Yuan Yuan Zhang, Jie Luo, Cheng Jin   +18 more
wiley   +1 more source

Engineering endosperm storage compartments enables simultaneous enrichment of multiple vitamins in rice

Journal of Integrative Plant Biology, EarlyView.
Engineering rice endosperm with modules for vitamin binding, lipid storage, and antioxidant protection enriched water‐ and fat‐soluble vitamins without compromising key agronomic traits and maintained vitamin higher levels after cooking, demonstrating its potential to improve crop nutrition.
Xingwei Cai, Huanteng Hou, Yuanyue Wang, Wenyao Tan, Haifeng Zhu, Mustafa Bulut, Zhuang Yang, Ran Xu, Xianqing Liu, Alisdair R. Fernie, Jie Li, Yufei Li, Jie Luo   +12 more
wiley   +1 more source

Association of Vitamin B6 and Homocysteine–ACTH Coupling With Depressive and Anxiety Symptoms in Burning Mouth Syndrome: An Exploratory Case–Control Study

Journal of Oral Rehabilitation, EarlyView.
In this exploratory case–control study, plasma PLP (vitamin B6), homocysteine and ACTH concentrations did not differ between patients with burning mouth syndrome (BMS) and controls, and none discriminated patients individually. Within patients, however, psychological distress mapped onto a homocysteine–ACTH relationship from which PLP appeared ...
Ashley Lebel, Charlotte Guillouet, André Porporatti, Yves Boucher   +3 more
wiley   +1 more source

Effect of Two Therapeutic Renal Diets on Hormonal and Regulatory Pathways Affecting Calcium Homeostasis in Cats With Early‐Stage Chronic Kidney Disease

Journal of Animal Physiology and Animal Nutrition, EarlyView.
ABSTRACT Chronic kidney disease (CKD) is a known risk factor for hypercalcemia in cats. Phosphate‐restricted diets have also been implicated in causing hypercalcemia, in part because phosphate restriction increases the Ca:P ratio. The primary objective of this study was to evaluate the impact of two different therapeutic renal foods on ionized (iCa ...
Jean A. Hall, Elizabeth M. Morris, Dale A. Fritsch, John J. Brejda, Kim M. Wilson   +4 more
wiley   +1 more source