Comprehensive and quantitative profiling of B vitamins and related compounds in the mammalian liver [PDF]
, 2020 A method for the simultaneous quantification of B vitamins and related amines in one-carbon (1C) metabolism would benefit the study of diet and genetic/epigenetic regulation of mammalian development and health.
Barrett, David +4 more
core +2 more sources
Reaction of pyridoxal-5′-phosphate with γ-carboxyglutamic acid [PDF]
Experientia, 1980 Pyridoxal-5′-phosphate (PLP) reacts with γ-carboxyglutamic acid (Gla) to form a stable complex absorbing at 325 nm. It is suggested that a condensation occurs in which the formyl group of PLP reacts with the α-amino group and the γ carbon atom of Gla to give a pyrrolidine derivative.
Laura Pecci +3 more
openaire +2 more sources
Urinary excretion of B-group vitamins reflects the nutritional status of B-group vitamins in rats
Journal of Nutritional Science, 2013 We have reported previously that the urinary excretion of B-group vitamins reflects recent dietary intakes of these vitamins. We also proposed reference values for the urinary levels of B-group vitamins for human subjects, and used these for evaluating ...
Katsumi Shibata +3 more
doaj +1 more source
Do glucocorticoids affect vitamin B6 metabolism in cells in which the steroid induces B6 dependent enzymes? [PDF]
, 1993 Two observations in the literature have led us to believe that glucocorticoids may affect the metabolism of the vitamers of pyridoxal-5-phosphate (PLP).
Sussmane, Shawn Tab
core +1 more source
Metabolome response to temperature-induced virulence gene expression in two genotypes of pathogenic Vibrio parahaemolyticus [PDF]
, 2016 Relative concentration of metabolites identified in Vibrio parahaemolyticus ATCC17802. (XLSX 113 kb)
Bo Feng +4 more
core +3 more sources
CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 5, Page 941-953, May 2025.ABSTRACT Coproporphyrin‐I (CP‐I) is a selective endogenous biomarker of organic anion‐transporting polypeptide (OATP)1B. Multiple CP‐I PBPK models with differing input parameters have been reported so far. This study proposed a harmonized CP‐I PBPK model and evaluated its ability to predict the effect of ethnicity, SLCO1B1 genotype c.521T>C, and sex on
Yuki Ujihira +3 more
wiley +1 more source
Chemistry of vitamin B6, molecular cloning of its related enzymes and reversible unfolding studies of myo-inositol monophosphatase with Hsc 70 [PDF]
, 1993 The main aims of this work are three-fold; first, to study chemical modification of proteins with vitamin B6 analogues, pyridoxamine or pyridoxamine-5\u27-phosphate and pyridoxic acid.
Kwon, On-Shin
core +1 more source
A comparison of complementary measures of vitamin B6 status, function, and metabolism in the European Prospective Investigation into Cancer and Nutrition (EPIC) study [PDF]
, 2021 Background: Vitamin B6 insufficiency has been linked to increased risk of cancer and other chronic diseases. The circulating concentration of pyridoxal 5'-phosphate (PLP) is a commonly used measure of vitamin B6 status.
Amiano, Pilar +35 more
core +4 more sources
Geometric-algebraic approach to aqueous solutions of diprotic acids and its buffer mixtures [PDF]
arXiv, 2023 A closed-form analytical expression for $\ce{[H3O+]}$ has been obtained for aqueous solutions of diprotic acids and its soluble salts. This formula allows to calculate the pH of aqueous solutions of diprotic acids, their buffer solutions, and the titrations of these two by a strong base, from the values of p$K_1$, p$K_2$, and the effective ...
arxiv
Systemic Activation of the Kynurenine Pathway in Graves Disease With and Without Ophthalmopathy [PDF]
, 2023 Context Graves disease (GD) is one of the most common autoimmune disorders. Recent literature has shown an immune response involving several different inflammatory related proteins in these patients.
Breivik, Lars Ertesvåg +9 more
core +2 more sources