Results 111 to 120 of about 1,181 (159)

Gut microbiome and metabolome profiles in renal allograft rejection from multiomics integration. [PDF]

mSystems
Dai X, Cao Y, Li L, Gao Y-X, Wang J-X, Liu Y-J, Ma T-T, Zheng J-M, Zhan P-P, Shen Z-Y.   +9 more
europepmc   +1 more source

Untargeted metabolomics reveals distinct biomarkers and metabolic alterations in familial and non-genetic hypercholesterolemia in Saudi patients. [PDF]

Front Med (Lausanne)
Al Mahdi HB, Shaik NA, Awan Z, Daghistani H, Alandejani F, Alghamdi KS, Obaid AA, Zahed R, Hassan RN, Edris S, Banaganapalli B, Mujalli A.   +11 more
europepmc   +1 more source

Water-Soluble Vitamins Stability by Robust Liquid Chromatography-Mass Spectrometry.

Ann Nutr Metab
Luo W, Wang D, Tang Y, Cheng Q, Ma X, Yu S, Qiu L.   +6 more
europepmc   +1 more source

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Measurement of pyridoxal 5′-phosphate, pyridoxal, and 4-pyridoxic acid in the cerebrospinal fluid of children

Clinica Chimica Acta, 2017
We quantified pyridoxal 5'-phosphate (PLP), pyridoxal (PL), and 4-pyridoxic acid (PA) in the cerebrospinal fluid (CSF) of children and to investigate the effect of age, sex, epilepsy, and anti-epileptic drug (AED) therapy on these vitamers.CSF samples prospectively collected from 116 pediatric patients were analyzed. PLP, PL, and PA were measured using
Tomoyuki Akiyama, Shin-Ichiro Hamano, Tohru Okanishi   +2 more
exaly   +3 more sources

Pyridoxal 5′-phosphate, pyridoxal, and 4-pyridoxic acid in the paired serum and cerebrospinal fluid of children

Clinica Chimica Acta, 2017
We quantified pyridoxal 5'-phosphate (PLP), pyridoxal (PL), and 4-pyridoxic acid (PA) in paired serum and cerebrospinal fluid (CSF) samples from children and investigated the effect of age on the concentrations and CSF-to-serum ratios of these vitamers.Serum and CSF samples prospectively collected from 49 pediatric patients were analyzed.
Tomoyuki Akiyama, Takashi Shibata, Hiroki Tsuchiya   +2 more
exaly   +3 more sources

Luminescence spectroscopy of pyridoxic acid and pyridoxic acid bound to proteins

FEBS Journal, 1994
Luminescence techniques, i.e. fluorescence and phosphorescence, have been employed to study pyridoxic acid bound to proteins through a stable amide linkage. Proteins tagged with 4‐pyridoxic acid display the following fluorescence properties: (a) emission and excitation spectra centered at around 430 and 320 nm, respectively; (b) fluorescence quantum ...
Oh-Shin Kwon, Manuel Blazquez, Jorge E Churchich   +2 more
exaly   +3 more sources

Identification of 5-pyridoxic acid and 5-pyridoxic acid lactone as metabolites of vitamin B6 in humans

Journal of Nutritional Biochemistry, 1991
Abstract Plasma and urine from individuals ingesting large amounts of vitamin B 6 contain several unidentified vitamin B 6 metabolites. Based on movement in 6 TLC solvents, elution in HPLC, and ultraviolet and infrared spectra, two of these metabolites have been identified as 5-pyridoxic acid and its lactone.
J D Mahuren, Stephen P Coburn
exaly   +2 more sources

Simultaneous and direct determination of pyridoxal, pyridoxal-5′-phosphate, and pyridoxic acid in serum by derivative synchronous fluorescence spectroscopy

Analytical Biochemistry, 1986
Simultaneous and direct assays of pyridoxal, pyridoxal-5'-phosphate, and pyridoxic acid in human serum are described. The method applied is based on the reaction of these compounds with beryllium in an ammoniacal medium to yield highly fluorescent derivatives.
Soledad Rubio, A Gómez-Hens
exaly   +3 more sources

A simple, sensitive and reproducible assay for pyridoxal 5′-phosphate and 4-pyridoxic acid in human plasma

Clinica Chimica Acta, 1999
We describe a procedure for the measurement of pyridoxal 5'-phosphate and of 4-pyridoxic acid in human plasma samples. It is based on the conversion of pyridoxal 5'-phosphate to 4-pyridoxic acid 5'-phosphate by cyanide in alkaline medium, followed by a high pressure liquid chromatographic separation, with fluorescence detection at acid pH. The assay is
Christopher J Bates, Kristina Pentieva, C J Bates   +2 more
exaly   +3 more sources