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Kinetics and Mechanism of the Condensation of Pyridoxal with Amino Acids

Russian Journal of General Chemistry, 2005
The kinetics and mechanism of the condensation of amino acids with pyridoxal were studied in relation to the amino acid structure, solvent, pH, and temperature. A spectrophotometric study revealed several kinetically discernible reaction steps. The condensation rate as a function of pH passes through a maximum, which is caused by formation of two ...
F. V. Pishchugin, I. T. Tuleberdiev
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Pyridoxal enzymes acting on D-amino acids

Pure and Applied Chemistry, 1994
Abstract
K. Soda, N. Esaki
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ChemInform Abstract: CATALYTIC ACTIVITIES OF PYRIDOXAL ANALOGUES PART 1, THE CATALYTIC EFFECTS OF PYRIDOXAL, PYRIDOXAL METHOCHLORIDE, AND PYRIDOXAL N‐OXIDE ON THE RACEMIZATION OF L‐GLUTAMIC ACID

Chemischer Informationsdienst, 1975
AbstractIn einer verbesserten Synthese werden ausgehend von Pyridoxal ‐ HCl (I) a) über die Stufen (II) und (III), das Methochlorid (IV) bzw. b) über die Stufen (II) und (V) das N‐Oxid (VI) dargestellt.
MAKOTO ANDO, SAKAE EMOTO
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Pyridoxal phosphate. 5. 2-Formylethynylphosphonic acid and 2-formylethylphosphonic acid, potent inhibitors of pyridoxal phosphate binding and probes of enzyme topography

Journal of Medicinal Chemistry, 1976
The title compounds (17 and 21) were prepared in good yield by synthesis of the phosphonate diester acetals (14 and 19), deesterification with chloro- or bromotrimethylsilane, hydrolysis of the acetal group, and formation of the characterized barium salts.
A J, Rudinskas, T L, Hullar
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Pyridoxal phosphate is not the acid catalyst in the glycogen phosphorylase catalytic mechanism

Biochemical and Biophysical Research Communications, 1982
Abstract Pyridoxal-reconstituted phosphorylase has been shown previously (Parrish, R.F., Uhing, R.J. and Graves, D.J. (1977), Biochemistry 16 , 4824) to be activated to a very similar extent by phosphite (pKa=6.6) and fluorophosphate (pKa=4.8).
S G, Withers, S, Shechosky, N B, Madsen
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Enantiomer Synthesis of Amino Acids with Pyridoxal Enzymes

1987
We here describe recent developments in the enzymatic synthesis of various optically active amino acids with pyridoxal enzymes including L-methionine γ-lyase, 0-acety1-homoserine (thiol)-lyase, D-amino acid aminotransferase, D-cysteine desulfhydrase, cystathionine γ-lyase, tryptophan synthase and amino acid racemases.
K. Soda   +3 more
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Inhibition of pyridoxal phosphokinase by aminooxyacetic acid

Biochemical Pharmacology, 1966
J P, DaVanzo   +3 more
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A direct method for preparing pyridoxal and 4‐pyridoxic acid

Journal of Heterocyclic Chemistry, 1967
H. Ahrens, W. Korytnyk
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Studies on the lactonization of 5 and 4-pyridoxic acid

Biochimica et Biophysica Acta, 1963
C J, ARGOUDELIS, F A, KUMMEROW
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