Results 141 to 150 of about 5,110,049 (220)

Broad Vitamin B₆-Related Metabolic Disturbances in a Zebrafish Model of Hypophosphatasia (TNSALP-Deficiency). [PDF]

Int J Mol Sci
Ciapaite J, Albersen M, Savelberg SMC, Bosma M, Meijer NWF, Tessadori F, Bakkers JPW, van Haaften G, Jans JJ, Verhoeven-Duif NM.   +9 more
europepmc   +1 more source

Vitamin B6 Turnover Predicts Long-term Mortality Risk in Patients with Type 2 Diabetes. [PDF]

Curr Dev Nutr
Li F, Liu X, Zhao L, Wang H, Zhang L, Xing W, Cui J.   +6 more
europepmc   +1 more source

Gut microbiota mitigate the reproductive toxicity of silver nanoparticles through thiamine-derived metabolites. [PDF]

Nat Commun
Gong JX, Wang XL, Lin CX, Li XY, Wu J, Tan QG, Yang L, Miao AJ.   +7 more
europepmc   +1 more source

Micronutrient Biomarker Selection and Assay Methods and Performance in Double-Blind, Randomized, Controlled Micronutrient Dose Response (MiNDR) Trials among Women of Reproductive Age and Pregnant Women in Rural Bangladesh. [PDF]

Curr Dev Nutr
Bandyopadhyay S, Roy AK, Baker S, Stephenson KK, Ge X, Wang Y, Ahsan KB, Zavala E, Ali H, Haque R, Wu LSF, Langevin B, Gopalakrishnan M, Siddiqua TJ, Hasan SMT, Christian P, Schulze KJ.   +16 more
europepmc   +1 more source

Rapid Determination of Water-Soluble Vitamins in Human Serum by Ultrahigh-Performance Liquid Chromatography-Tandem Mass Spectrometry. [PDF]

ACS Omega
Zhang M, Zhang C, Cai H, Xie Y, Chai L, Sun M, Liu J, Liu J, Yi C, Fan H, Yi W, Lv Z.   +11 more
europepmc   +1 more source

Pyridoxal 5′-phosphate, pyridoxal, and 4-pyridoxic acid in the paired serum and cerebrospinal fluid of children

Clinica Chimica Acta, 2017
We quantified pyridoxal 5'-phosphate (PLP), pyridoxal (PL), and 4-pyridoxic acid (PA) in paired serum and cerebrospinal fluid (CSF) samples from children and investigated the effect of age on the concentrations and CSF-to-serum ratios of these vitamers.Serum and CSF samples prospectively collected from 49 pediatric patients were analyzed.
Tomoyuki Akiyama, Yumiko Hayashi, Yoshiyuki Hanaoka, Takashi Shibata, Mari Akiyama, Hiroki Tsuchiya, Tokito Yamaguchi, Katsuhiro Kobayashi   +7 more
semanticscholar   +4 more sources

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Measurement of pyridoxal 5′-phosphate, pyridoxal, and 4-pyridoxic acid in the cerebrospinal fluid of children

Clinica Chimica Acta, 2017
We quantified pyridoxal 5'-phosphate (PLP), pyridoxal (PL), and 4-pyridoxic acid (PA) in the cerebrospinal fluid (CSF) of children and to investigate the effect of age, sex, epilepsy, and anti-epileptic drug (AED) therapy on these vitamers.CSF samples prospectively collected from 116 pediatric patients were analyzed. PLP, PL, and PA were measured using
Tomoyuki Akiyama, Mari Akiyama, Yumiko Hayashi, Takashi Shibata, Yoshiyuki Hanaoka, Soichiro Toda, Katsumi Imai, Shin-ichiro Hamano, Tohru Okanishi, Harumi Yoshinaga, Katsuhiro Kobayashi   +10 more
openaire   +3 more sources

New Pathway of Conversion of Pyridoxal to 4-Pyridoxic Acid

Enzyme, 1976
The only enzyme demonstrated so far to catalyze the formation of 4-pyridoxic acid, the final excretory product of vitamin B6, was aldehyde oxidase. In this paper we have presented an evidence that another enzyme, NAD+-dependent aldehyde dehydrogenase, is capable of catalyzing this reaction.
M, Stanulović, V, Jeremić, V, Leskovac, S, Chaykin   +3 more
openaire   +3 more sources

Determination of urinary 4-pyridoxic acid levels as 4-pyridoxic acid lactone using high-performance liquid chromatography

The American Journal of Clinical Nutrition, 1986
A high-performance liquid chromatography method for quantitation of urinary 4-pyridoxic acid excretion is presented. Urine samples were treated with HCl to form 4-pyridoxic acid lactone. Acid-treated urine samples were diluted and analyzed by cation-exchange chromatography involving post-column alkalinization and fluorescence detection.
JB Ubbink, WJ Serfontein, PJ Becker, LS De Villiers   +3 more
openalex   +3 more sources

Assessing the Effect of Organic Anion Transporter Inhibition on Circulating Pyridoxic Acid, an Endogenous Transporter Biomarker, using Physiologically‐based Pharmacokinetic Modeling

The FASEB Journal, 2022
Transporter‐mediated renal secretion plays a critical role in the systemic clearance of ~30% of the Food and Drug Administration (FDA)‐approved drugs and is attributed to clinically significant drug‐drug interactions (DDIs).
Aarzoo Thakur, B. Prasad
semanticscholar   +1 more source