Results 31 to 40 of about 1,181 (159)

Pyridoxal and Pyridoxamine Phosphate Breakdown by an Acid Phosphatase Preparation [PDF]

Nature, 1966
DURING investigations of the controlled inactivation of pyridoxal phosphate-dependent enzymes, an acid phosphatase preparation has been used to effect co-enzyme destruction. Alkaline phosphatases of mammalian origin are known to hydrolyse both pyridoxal and pyridoxamine phosphates1,2 and an alkaline phosphatase preparation from E.
M J, Andrews, J M, Turner
openaire   +2 more sources

Liver Transplantation in PNPO Deficiency: Management Challenges and Biological Lessons. [PDF]

JIMD Rep
ABSTRACT Pyridox(am)ine 5′ Phosphate Oxidase deficiency (PNPO) presents with refractory epilepsy responsive to treatment with pyridoxal 5′ phosphate (PLP) or pyridoxine. A 15‐year‐old boy with PNPO deficiency and cirrhosis underwent orthotopic liver transplantation for hepatocellular carcinoma without extra‐hepatic disease.
Webster R, Sankaran BP, Bandodkar S, Stormon M, Thomas G, Shun A, Bowen DG, Fielder T, Barclay P, Khalil Y, Mills P, Clayton P, Bhattacharya K.   +12 more
europepmc   +2 more sources

Elevated plasma 4-pyridoxic acid in renal insufficiency [PDF]

The American Journal of Clinical Nutrition, 2002
Renal insufficiency is associated with altered vitamin B-6 metabolism. We have observed high concentrations of 4-pyridoxic acid, the major catabolite of vitamin B-6 metabolism, in plasma during renal insufficiency.The objective was to evaluate the renal handling of 4-pyridoxic acid and the effects of renal dysfunction on vitamin B-6 metabolism.We ...
Stephen P, Coburn, Robert D, Reynolds, J Dennis, Mahuren, Wayne E, Schaltenbrand, Yao, Wang, Karen L, Ericson, Michael P, Whyte, Yvonne M, Zubovic, Paula J, Ziegler, David L, Costill, William J, Fink, David R, Pearson, Thomas A, Pauly, K George, Thampy, Jacobo, Wortsman   +14 more
openaire   +2 more sources

Effect of Astragalus membranaceus Root on the Serum Metabolome of Preweaning Dairy Calves

Agriculture, 2022
The effect of the Astragalus membranaceus root (AMR) on the serum metabolic profiles of preweaning calf were investigated in this study. Sixteen preweaning Holstein calves were randomly allocated into two groups with eight calves per group, and offered a
Li Ma, Zhengzhong Luo, Jiubing Chen, Zhenlong Du, Tao Zhou, Yixin Huang, Xueping Yao, Liuhong Shen, Shumin Yu, Xiaodong Shi, Suizhong Cao   +10 more
doaj   +1 more source

Untargeted Metabolomics to Explore the Bacteria Exo-Metabolome Related to Plant Biostimulants

Agronomy, 2022
The control and development of plant growth promoters is a key factor for the agro-nomy industry in its economic performance. Different genera of bacteria are widely used as natural biostimulants with the aim of enhancing nutrition efficiency, abiotic ...
Carlos J. García, Verónica Alacid, Francisco A. Tomás-Barberán, Carlos García, Pedro Palazón   +4 more
doaj   +1 more source

Electrochemical Analysis on Compounds of the Vitamin B6 Family Using Glassy Carbon Electrodes

International Journal of Electrochemical Science, 2012
The electrochemical reduction of vitamin B6 group and related compounds has been performed at pH neutral using glassy carbon electrodes. Irreversible bi- or tetra-electronic processes controlled by diffusion on the top of the wave are observed for these ...
J. Gonzalez-Rodriguez, J.M. Sevilla, T. Pineda, M. Blazquez   +3 more
doaj   +1 more source

Development and validation of an LC-MS/MS method for determination of B vitamins and some its derivatives in whole blood.

PLoS ONE, 2022
Obligate symbiotic bacteria associated with the insects feeding exclusively on vertebrate blood are supposed to complement B vitamins presumably lacking in their diet.
David Kahoun, Pavla Fojtíková, František Vácha, Marie Čížková, Roman Vodička, Eva Nováková, Václav Hypša   +6 more
doaj   +1 more source

Effect of pyridoxal administration on the contents of pyridoxal phosphate and .GAMMA.-aminobutyric acid in mouse brain.

Journal of Nutritional Science and Vitaminology, 1978
Many mice treated with a high single dose of PL died in convulsions. The convulsions were very similar to those induced with some anti B6 in several ways: (1) a long latent period occurs betfore convulsions; (2) PLP levels in brain decrease; (3) GABA levels in brain, especially in synaptosomal fraction, decrease.
ETO, Kimiharu, TAKAHASHI, Yasuko, HOSHINO, Michio, SAKURAI, Tae, MATSUDA, Makoto   +4 more
openaire   +3 more sources

Therapeutic Effect and Mechanism of Si-Miao-Yong-An-Tang on Thromboangiitis Obliterans Based on the Urine Metabolomics Approach

Frontiers in Pharmacology, 2022
Si-Miao-Yong-An-Tang (SMYAT) is a classic prescription for the treatment of thromboangiitis obliterans (TAO). However, the effect and mechanism are still unclear.
Hui-Yu Li, Hui-Yu Li, Hui Sun, Ai-Hua Zhang, Lu-Wen He, Shi Qiu, Jun-Ru Xue, Fangfang Wu, Xi-Jun Wang, Xi-Jun Wang, Xi-Jun Wang   +10 more
doaj   +1 more source

Multiomics Reveals the Microbiota and Metabolites Associated with Sperm Quality in Rongchang Boars

Microorganisms
In this study, we investigated the correlation between the composition and function of the gut microbiota and the semen quality of Rongchang boars. Significant differences in gut microbial composition between boars with high (group H) and low (group L ...
Chao A, Bin Zhang, Jie Chai, Zhi Tu, Zhiqiang Yan, Xiaoqian Wu, Minghong Wei, Chuanyi Wu, Tinghuan Zhang, Pingxian Wu, Mingzhou Li, Li Chen   +11 more
doaj   +1 more source