Results 161 to 170 of about 3,638 (238)
Novel potentiometric sensors for pyrilamine maleate
Journal of the Iranian Chemical Society, 2017 The fabrication and electrochemical response characteristics of four novel potentiometric sensors for determination of pyrilamine maleate (PyraH) were described. The sensors include polymeric membrane electrodes (PME1, PME2) and carbon paste electrodes (CPE1, CPE2).
Mohamed Magdy Khalil
exaly +5 more sources
Pyrilamine inhibits nicotine-induced catecholamine secretion
Neurochemistry International, 2014 Function of nicotine, which induces activation of all parts of the body including our brain, has been receiving much attention for a long period of time and also been actively studied by researchers for its pharmacological actions in the central nervous system.
Kim, DC +7 more
semanticscholar +6 more sources
European Journal of Obstetrics & Gynecology and Reproductive Biology, 2011 To evaluate the interaction type of the human uterine relaxant effect of the paracetamol-pyrilamine combination (PPC) in vitro.Uterine strips were contracted with KCl (60 mM) and treated with vehicle or increasing concentrations of paracetamol (100-3200 μM), pyrilamine (3.2-100 μM) or the PPC.
Héctor A. Ponce-Monter +4 more
semanticscholar +5 more sources
Chromatographic Analysis of Chlorpheniramine, Pyrilamine, and Methapyrilene in Combination
Journal of Pharmaceutical Sciences, 1969 A partition chromatographic method is presented for the separation and quantitation of chlorpheniramine, methapyrilene, and pyrilamine in combination.A solution of p-toluenesulfonic acid and potassium chloride on a column of diatomaceous earth is used to effect the separation.The isolated chlorpheniramine is determined by UV spectrophotometry.The ...
Bobby R. Rader
openaire +4 more sources
The metabolism and elimination of pyrilamine maleate in the rat.
Drug Metabolism and Disposition, 1987 The metabolism and elimination of pyrilamine (2-[(2-dimethylamino-ethyl)(p-methoxybenzyl)amino]pyridine) were characterized after the iv administration of 7.0 mg/kg or 0.7 mg/kg pyrilamine maleate plus [14C]pyrilamine maleate to adult male Fischer-344 rats.
D W, Kelly, W, Slikker
openaire +3 more sources
Journal of Pharmaceutical Sciences, 1969 The experiments described herein were performed on isolated, spontaneously beating rabbit atria. The muscarinic actions of acetylcholine in the presence of physostigmine were antagonized by pyrilamine, chlorpheniramine and procaine which demonstrates that these drugs have an “antimuscarinic” action.
Theodore Koppanyi, Robert E. Osterberg
openaire +4 more sources
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Effects of chlorpheniramine, pyrilamine and astemizole on intracranial self-stimulation in rats
European Journal of Pharmacology, 1981Rats implanted in the lateral hypothalamus were used to assess lever pressing for brain stimulation. Lever pressing was increased dose-dependently by chlorpheniramine and decreased dose-dependently by pyrilamine. Astemizole, a new orally long-acting antihistamine did not affect self-stimulation.
Albert Wauquier, Carlos J. E. Niemegeers
openaire +4 more sources
Pyrilamine-Induced Prolonged QT Interval in Adolescent With Drug Overdose
Pediatric Emergency Care, 2011The widespread availability of antihistamines in many over-the-counter preparations can lead to significant hazard to the public because of their possible link to potential ventricular arrhythmias secondary to prolongation of QT interval. The effect can be further compounded by the use of other commonly used medications such as macrolides, antifungal ...
Sarika Kalantre +3 more
openaire +4 more sources
Effect of tracer metabolism on PET measurement of [11C]pyrilamine binding to histamine H1 receptors
Annals of Nuclear Medicine, 1999 The present study was carried out to investigate the time course of [11C]pyrilamine metabolism and the degree of entry of metabolites into the brain. PET studies were performed in seven healthy volunteers and arterial plasma concentrations of [11C]pyrilamine and its labeled metabolites were determined.
Ursula Scheffel +6 more
openaire +4 more sources