Results 31 to 40 of about 1,774 (189)

Functional expression of a proton-coupled organic cation (H+/OC) antiporter in human brain capillary endothelial cell line hCMEC/D3, a human blood–brain barrier model

open access: yesFluids and Barriers of the CNS, 2013
Background Knowledge of the molecular basis and transport function of the human blood–brain barrier (BBB) is important for not only understanding human cerebral physiology, but also development of new central nervous system (CNS)-acting drugs.
Shimomura Keita   +6 more
doaj   +1 more source

Prevalence, impact and treatment of primary dysmenorrhea in workers of an Academic and Research Institute

open access: yesMexican Journal of Medical Research ICSA, 2013
Dysmenorrhea is one of the cyclical processes in chronic pelvic pain. Dysmenorrhea in women causes a high psychosocial and economic impact. For this reason, we conducted a study to assess the prevalence, impact and use of drugs for the treatment of ...
Héctor A. Ponce-Monter   +8 more
doaj   +1 more source

Histamine activates an intracellular Ca2+ signal in normal human lung fibroblast WI-38 cells

open access: yesFrontiers in Cell and Developmental Biology, 2022
Histamine is an inflammatory mediator that can be released from mast cells to induce airway remodeling and cause persistent airflow limitation in asthma.
Roberto Berra-Romani   +11 more
doaj   +1 more source

Simultaneous Determination of Acetaminophen, Pamabrom and Pyrilamine Maleate in Pharmaceutical Formulations Using Stability Indicating HPLC Assay Method

open access: yes, 2017
A simple, specific and accurate stability indicating RPHPLC method was developed for the determination of acetaminophen, pamabrom and pyrilamine maleate simultaneously in pharmaceutical dosage forms.
Muhammad Ashfaq
core   +2 more sources

Hippocampal histamine receptors and conflictive exploration in the rat: studies using the elevated asymmetric plus-maze

open access: yesBrazilian Journal of Medical and Biological Research, 1997
The possible role of histamine receptors in the hippocampal formation on the exploratory motivation and emotionality of the rat was studied. An elevated asymmetric plus-maze composed of 4 different arms (no walls, single high wall, high and low walls and
M.B. Ruarte, A.G. Orofino, E.O. Alvarez
doaj   +1 more source

Subchronic Studies of Pyrilamine in B6C3F1 Mice

open access: yes, 1993
The purpose of this study was to determine the effects of subchronic exposure to the antihistamine pyrilamine maleate and to establish dosage levels to use in a 2-year chronic study. A 14-day repeated-dose study in male and female B6C3F1 mice at dietary
David W. Gaylor   +3 more
core   +1 more source

The Effects of Histaminergic Agents in the Nucleus ccumbens of Rats in the Elevated Plus-Maze Test of Anxiety [PDF]

open access: yesIranian Journal of Psychiatry, 2010
"n Objective: "n The nucleus accumbens (NAc) receive histaminergic neurons from tuberomammillary nuclei. There are reports indicating that central histamine systems are involved in many physiological behavioral processes, including anxiety.
Ameneh Rezayof   +2 more
doaj  

The Influence of Mast Cell Mediators on Migration of SW756 Cervical Carcinoma Cells

open access: yesJournal of Pharmacological Sciences, 2008
The role of mast cell mediators on cervical cancer cell migration was assessed using an in vitro assay of scratch wound healing onto monolayers of HPV18-positive cervical carcinoma cells (SW756).
M. Isolde Rudolph   +7 more
doaj   +1 more source

Enhanced vascular permeability facilitates entry of plasma HDL and promotes macrophage-reverse cholesterol transport from skin in mice

open access: yesJournal of Lipid Research, 2015
Reverse cholesterol transport (RCT) pathway from macrophage foam cells initiates when HDL particles cross the endothelium, enter the interstitial fluid, and induce cholesterol efflux from these cells.
Ilona Kareinen   +9 more
doaj   +1 more source

Effect of histamine and compound 48/80 on the conduction of vasodilation in the presence of pyrilamine.

open access: yes, 2019
Pyrilamine abolished the effect of histamine on reducing conducted vasodilation but combination of C48/80 and pyrilamine, a significant reduction in conducted vasodilation was still observed.
Keith N. Egger (7300358)   +8 more
core   +1 more source

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