Results 31 to 40 of about 1,693 (192)

Involvement of the pyrilamine transporter, a putative organic cation transporter, in blood-brain barrier transport of oxycodone [PDF]

open access: yes, 2008
The purpose of this study was to characterize blood-brain barrier (BBB) transport of oxycodone, a cationic opioid agonist, via the pyrilamine transporter, a putative organic cation transporter, using conditionally immortalized rat brain capillary ...
Sato, Takenori   +13 more
core   +1 more source

Histaminergic modulation of cholinergic release from the nucleus basalis magnocellularis into insular cortex during taste aversive memory formation. [PDF]

open access: yesPLoS ONE, 2014
The ability of acetylcholine (ACh) to alter specific functional properties of the cortex endows the cholinergic system with an important modulatory role in memory formation. For example, an increase in ACh release occurs during novel stimulus processing,
Liliana Purón-Sierra   +1 more
doaj   +1 more source

Spectrophotometric Determination of Various Drugs Using Chloranilic Acid as Chromogenic Reagent - II

open access: yesE-Journal of Chemistry, 2010
Simple, accurate and reproducible visible spectrophotometric method for the assay of drugs such as pyrilamine and fluvoxamine as maleates was established based on the formation of charge-transfer complex and redox reaction between the corresponding drug ...
V. Annapurna   +3 more
doaj   +1 more source

Functional expression of a proton-coupled organic cation (H+/OC) antiporter in human brain capillary endothelial cell line hCMEC/D3, a human blood–brain barrier model

open access: yesFluids and Barriers of the CNS, 2013
Background Knowledge of the molecular basis and transport function of the human blood–brain barrier (BBB) is important for not only understanding human cerebral physiology, but also development of new central nervous system (CNS)-acting drugs.
Shimomura Keita   +6 more
doaj   +1 more source

Simultaneous Determination of Acetaminophen, Pamabrom and Pyrilamine Maleate in Pharmaceutical Formulations Using Stability Indicating HPLC Assay Method [PDF]

open access: yes, 2017
A simple, specific and accurate stability indicating RPHPLC method was developed for the determination of acetaminophen, pamabrom and pyrilamine maleate simultaneously in pharmaceutical dosage forms.
Muhammad Ashfaq
core   +1 more source

Additional file 3 of Disruption of histamine/H1R signaling pathway represses cardiac differentiation and maturation of human induced pluripotent stem cells [PDF]

open access: yes, 2020
Additional file 3: : Video 1 The morphology and beating behavior of zebrafish after pyrilamine treatment at 96 hours post ...
Zhiwei Zhang (12077)   +9 more
core   +1 more source

Prevalence, impact and treatment of primary dysmenorrhea in workers of an Academic and Research Institute

open access: yesMexican Journal of Medical Research ICSA, 2013
Dysmenorrhea is one of the cyclical processes in chronic pelvic pain. Dysmenorrhea in women causes a high psychosocial and economic impact. For this reason, we conducted a study to assess the prevalence, impact and use of drugs for the treatment of ...
Héctor A. Ponce-Monter   +8 more
doaj   +1 more source

Histamine activates an intracellular Ca2+ signal in normal human lung fibroblast WI-38 cells

open access: yesFrontiers in Cell and Developmental Biology, 2022
Histamine is an inflammatory mediator that can be released from mast cells to induce airway remodeling and cause persistent airflow limitation in asthma.
Roberto Berra-Romani   +11 more
doaj   +1 more source

Hippocampal histamine receptors and conflictive exploration in the rat: studies using the elevated asymmetric plus-maze

open access: yesBrazilian Journal of Medical and Biological Research, 1997
The possible role of histamine receptors in the hippocampal formation on the exploratory motivation and emotionality of the rat was studied. An elevated asymmetric plus-maze composed of 4 different arms (no walls, single high wall, high and low walls and
M.B. Ruarte, A.G. Orofino, E.O. Alvarez
doaj   +1 more source

The Effects of Histaminergic Agents in the Nucleus ccumbens of Rats in the Elevated Plus-Maze Test of Anxiety [PDF]

open access: yesIranian Journal of Psychiatry, 2010
"n Objective: "n The nucleus accumbens (NAc) receive histaminergic neurons from tuberomammillary nuclei. There are reports indicating that central histamine systems are involved in many physiological behavioral processes, including anxiety.
Ameneh Rezayof   +2 more
doaj  

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