Results 71 to 80 of about 3,638 (238)
Stem Cell Research & Therapy, 2020 Background The efficiency and quality of human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) are crucial for regenerative medicine, disease modeling, drug screening, and the study of the development events during cardiac specification.
Xiaowei Zhu +9 more
doaj +1 more source
Contact Dermatitis, Volume 90, Issue 3, Page 253-261, March 2024.Ongoing surveillance on prevalence of contact sensitization contributes to maintaining an up‐to‐date standard series in different geographical areas. Contact allergy to EDD yielded a sensitization prevalence <1% in recent years in northeastern Italy, and we therefore consider no longer justifiable to include this hapten in our baseline patch test ...
Linda Piapan +3 more
wiley +1 more source
Combination Therapies of the Neurotransmitter-Targeting Drugs Dextromethorphan, Pyrilamine and Lorcaserin in a Rat Model of Nicotine Addiction [PDF]
, 2014 Given the current epidemic of nicotine dependence, the study of interactions between neurotransmitter receptor-targeting molecules to discover possible new forms of smoking cessation treatment is of great importance.
Briggs, Scott
core +1 more source
Iranian Journal of Psychiatry, 2010 Objective: The nucleus accumbens (NAc) receive histaminergic neurons from tuberomammillary nuclei. There are reports indicating that central histamine systems are involved in many physiological behavioral processes, including anxiety.
Mohammad-Reza Zarrindast +2 more
doaj +2 more sources
Melatonin Is Required for the Circadian Regulation of Sleep [PDF]
, 2015 Sleep is an evolutionarily conserved behavioral state whose regulation is poorly understood. A classical model posits that sleep is regulated by homeostatic and circadian mechanisms.
Gandhi, Avni V. +3 more
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Journal of Pharmacological Sciences, 2010 This study was performed to investigate the ameliorative effects of metabotropic glutamate (mGlu)-receptor agonists on histamine H1 receptor antagonist–induced spatial memory deficit and the decrease in hippocampal theta activity in rats. Intraperitoneal
Takayoshi Masuoka +2 more
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Frontiers in Pharmacology, 2018 G-protein-coupled receptors (GPCRs) are membrane proteins distributed on the cell surface, and they may be potential drug targets. However, synthesizing GPCRs in vitro can be challenging. Recently, some cell-free protein synthesis systems have been shown
Yasuyuki Suzuki +7 more
doaj +1 more source
Morphine modulates the effects of histamine H1 and H3 receptors on seizure susceptibility in pentylenetetrazole-induced seizure model of mice [PDF]
, 2015 Histamine regulates release of neurotransmitters such as dopamine, serotonin, gamma-aminobutyric acid (GABA), glutamate and also is involved in several functions in central nervous system (CNS).
Alijanpour, Sakineh. +9 more
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Species and tissue-specificity of prokinetic, laxative and spasmodic effects of Fumaria parviflora [PDF]
, 2012 Background Fumaria parviflora Linn. (Fumariaceae), is a small branched annual herb found in many parts of the world including Saudi Arabia and Pakistan. This study was designed to provide pharmacological basis for the medicinal use of Fumaria parviflora ...
AA Izzo +40 more
core +4 more sources
Journal of Pharmacological Sciences, 2008 The aim of this study was to investigate the effects of histamine H1 and H3 antagonists on learning and mnemonic dysfunction in mice. Two H1 antagonists, pyrilamine and clozapine, and the prototypic H3 antagonist thioperamide were used to study the role ...
Feiyong Jia +9 more
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