Results 41 to 50 of about 34,530 (252)

Adherence to the combination of sulphadoxine-pyrimethamine and artesunate in the Maheba refugee settlement, Zambia. [PDF]

, 2004
Artemisinin-based combination therapy (ACT) is one strategy recommended to increase cure rates in malaria and to contain resistance to Plasmodium falciparum. In the Maheba refugee settlement, children aged 5 years or younger with a confirmed diagnosis of
Balkan, S, Depoortere, E, Fermon, F, Guthmann, J P, Legros, D, Nkandu, E, Sipilanyambe, N   +6 more
core   +2 more sources

Efficacy of chloroquine, sulphadoxine-pyrimethamine and amodiaquine for treatment of uncomplicated Plasmodium falciparum malaria in Kajo Keji county, Sudan. [PDF]

, 2004
To provide advice on the rational use of antimalarial drugs, Médecins Sans Frontières conducted a randomized, an open label efficacy study in Kajo Keji, an area of high transmission of malaria in southern Sudan.
Epicentre, Krishna S, Kshirsagar NA, National Malaria Administration/Unicef, Ochong EO, Omari AA, Seidlein L, UN/OCHA, Vugt M, WHO, WHO, WHO, WHO, WHO/Roll Back Malaria   +13 more
core   +2 more sources

Antiplasmodial Activity and Pharmacokinetic Profiling of Cryptolepine and 2,7‐Dibromocryptolepine With a View to Informing the Design of Novel Antimalarial Cryptolepine Analogues

Drug Development Research, Volume 87, Issue 2, April 2026.
ABSTRACT The roots of the climbing shrub Cryptolepis sanguinolenta are traditionally used in West Africa for the treatment of malaria. The principal constituent, cryptolepine (1), has been shown to have antimalarial activity but there are concerns regarding its toxicity on account of its DNA‐intercalating property.
Elodie Chenu, James Duffy, Arnold Donkor Forkuo, Stephen Y. Gbedema, Seham Abdelall, Muhammad Wahajuddin, Huw S. Jones, Colin W. Wright   +7 more
wiley   +1 more source

Amitriptyline Induced Life‐Threatening Steven–Johnson Syndrome: Case Report

Clinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT Stevens–Johnson syndrome is one of the few dermatological emergencies in clinical practice. The syndrome is often secondary to the usage of drugs, of which allopurinol, penicillins, sulfa drugs, ibuprofen, sodium valproate, phenytoin, lamotrigine, and carbamazepine are commonly implicated.
Wondwosen Mengist Dereje, Lidya Yalew, Nardos Tafesse, Teklegiorgis Goshime Getachew   +3 more
wiley   +1 more source

Responsiveness of emergency obstetric care systems in low- and middle-income countries: a critical review of the "third delay". [PDF]

, 2012
We reviewed the evidence on the duration, causes and effects of delays in providing emergency obstetric care to women attending health facilities (the third delay) in low- and middle-income countries. We performed a critical literature review using terms
Cavallaro, Francesca L, Marchant, Tanya J   +1 more
core   +1 more source

Trends and Patterns of Adverse Drug Reaction Reporting in Sierra Leone: A Retrospective Analysis of VigiFlow Data (2008–2022)

Pharmacoepidemiology and Drug Safety, Volume 35, Issue 3, March 2026.
ABSTRACT Purpose Adverse drug reactions (ADRs) present significant obstacles for healthcare systems, impacting both patient safety and the effectiveness of treatments. Despite this, there is a scarcity of research on ADR reports in Sierra Leone, especially over long periods.
Isatu Jalloh, Onome Thomas Abiri, Peter Bai James, Rajesh Vagiri, Neelaveni Padayachee   +4 more
wiley   +1 more source

Invasive bacterial infections in Gambians with sickle cell anaemia in an era of widespread Pneumococcal and Haemophilus influenzae type B vaccination [PDF]

, 2016
Background: There is relatively little data on the aetiology of bacterial infections in patients with sickle cell anaemia (SCA) in West Africa, and no data from countries that have implemented conjugate vaccines against both Streptococcus pneumoniae and ...
Anderson, ST, Bah, G, Cunnington, A, Darboe, S, Lawal, B, Soothill, G   +5 more
core   +1 more source

Childhood Linear Growth and Early Morbidity as Predictors of Adolescent Cognitive Ability in Malawi: A Prospective Observational Study

Acta Paediatrica, Volume 115, Issue 3, Page 634-642, March 2026.
ABSTRACT Aim Growth faltering and loss of development potential are common in low‐ and middle‐income countries. We aimed to study whether linear growth before and after 2 years, height‐for‐age Z‐score (HAZ) from 1 month until 13 years and morbidity during the first 3 years predict adolescent cognitive ability.
Karoliina Videman, Jukka M. Leppänen, Lotta Hallamaa, Kenneth Maleta, Per Ashorn, Charles Mangani, Ulla Ashorn   +6 more
wiley   +1 more source

Response to Buffet et al: Intermittent preventive anti-malarial treatment to children (IPTc): firebreak or fire trap?

, 2008
Buffet and colleagues have reviewed some of the potential benefits and drawbacks of intermittent preventive antimalarial treatment in children (IPTc).
Bojang, Kalifa, Chandramohan, Daniel, Cisse, Badara, Greenwood, Brian, Kweku, Margaret, Milligan, Paul   +5 more
core   +1 more source

Adherence to a Six-Dose Regimen of Artemether-Lumefantrine for Treatment of Uncomplicated Plasmodium Falciparum Malaria in Uganda. [PDF]

, 2004
Measuring baseline levels of adherence and identifying risk factors for non-adherence are important steps before the introduction of new antimalarials. In Mbarara in southwestern Uganda, we assessed adherence to artemether-lumefantrine (Coartem) in its ...
Bajunirwe, F, Biraro, S, Checchi, F, Fogg, C, Guthmann, J P, Kiguli, J, Kyomugisha, A, Musabe, J, Namiiro, P, Piola, P   +9 more
core   +2 more sources