Results 41 to 50 of about 43,381 (288)

Sulfadoxine-Pyrimethamine Exhibits Dose-Response Protection Against Adverse Birth Outcomes Related to Malaria and Sexually Transmitted and Reproductive Tract Infections

Clinical Infectious Diseases, 2017
Summary Compared to 0–1 dose of intermittent preventive treatment of malaria using sulfadoxine-pyrimethamine, ≥2 doses protects pregnant women against adverse birth outcomes attributable to malaria infection and to curable sexually transmitted and ...
R. Chico, E. B. Chaponda, E. B. Chaponda, C. Ariti, D. Chandramohan   +4 more
semanticscholar   +1 more source

Perspective for the reproduction of antimalarial drugs in Brazil

Memorias do Instituto Oswaldo Cruz, 1992
The appears to be no chemical manufacture of antimalarial drugs is Brazil. Technology at laboratory process level has been developed for chloroquine, mefloquine, pyrimethamine and cycloquanil, but not perfected nor scaled-up, largely for economic reasons
Benjamin Gilbert
doaj   +1 more source

A new effective antiplasmodial compound: Nanoformulated pyrimethamine

Journal of Global Antimicrobial Resistance, 2020
Objectives: The aim of this study was to evaluate the efficacy of pyrimethamine-loaded poloxamer 407 nanomicelles on Plasmodium berghei strain NICD in vivo.
Nader Pestehchian, Mohammad Reza Vafaei, Pardis Nematolahy, Jaleh Varshosaz, Hossein Ali Yousefi, Vahab Ziaei Bide, Hamed Kalani   +6 more
doaj   +1 more source

Intermittent preventive treatment of malaria provides substantial protection against malaria in children already protected by an insecticide-treated bednet in Burkina Faso: a randomised, double-blind, placebo-controlled trial. [PDF]

, 2011
BACKGROUND: Intermittent preventive treatment of malaria in children (IPTc) is a promising new approach to the control of malaria in areas of seasonal malaria transmission but it is not known if IPTc adds to the protection provided by an insecticide ...
Chandramohan, Daniel, Cousens, Simon, Diallo, Diadier A, Diarra, Amidou, Gansané, Adama, Greenwood, Brian, Kaboré, Youssouf, Kangoyé, David T, Konaté, Amadou T, Milligan, Paul J, Ouédraogo, Alphonse, Ouédraogo, Amidou Z, Ouédraogo, Espérance, Ouédraogo, Issa N, Sirima, Sodiomon B, Soulama, Issiaka, Tiono, Alfred B, Yaro, Jean Baptiste   +17 more
core   +3 more sources

Molecular markers of resistance to amodiaquine plus sulfadoxine–pyrimethamine in an area with seasonal malaria chemoprevention in south central Niger

Malaria Journal, 2018
In Niger, malaria transmission is markedly seasonal with most of the disease burden occurring in children during the rainy season. Seasonal malaria chemoprevention (SMC) with amodiaquine plus sulfadoxine–pyrimethamine (AQ + SP) is recommended in the ...
R. Grais, I. Laminou, Lynda Woi-Messe, Rockyath Makarimi, Seidou H. Bouriema, C. Langendorf, A. Amambua-Ngwa, U. d’Alessandro, P. Guérin, T. Fandeur, C. Sibley   +10 more
semanticscholar   +1 more source

Risk of Congenital Toxoplasmosis in Newborns from Mothers with Documented Infection: Experience from Two Referral Centres

Pathogens
During pregnancy, primary Toxoplasma gondii infection can cause congenital toxoplasmosis (CT). We described the newborns’ outcomes from a multicentre cohort of mothers with seroconversion (SC) at different gestational ages.
Alice Bonetti, Agnese Comelli, Annacarla Chiesa, Vania Spinoni, Ambra Vola, Federico Prefumo, Adriana Valcamonico, Carlo Bonfanti, Silvio Caligaris, Lina Rachele Tomasoni, Fausto Baldanti, Valeria Meroni   +11 more
doaj   +1 more source

Options for clinical trials of pre and post-natal treatments for congenital toxoplasmosis

Memorias do Instituto Oswaldo Cruz, 2009
Clinical trials comparing different drug regimens and strategies for the treatment of congenital toxoplasmosis and its clinical manifestations in the liveborn child in different clinical settings should aim at formally evaluating the net benefit of ...
Geneviève Chêne, Rodolphe Thiébaut
doaj   +1 more source

Drug resistance in Plasmodium falciparum from the Chittagong Hill Tracts, Bangladesh. [PDF]

, 2004
OBJECTIVE: To assess the efficacy of antimalarial treatment and molecular markers of Plasmodium falciparum resistance in the Chittagong Hill Tracts of Bangladesh. METHODS: A total of 203 patients infected with P.
Anderson, T C, Brockman, A, Chakma, S, Nair, S, Talukder, L, van den Broek, I, van der Wardt, S   +6 more
core   +2 more sources

Community-based Malaria Screening and Treatment for Pregnant Women Receiving Standard Intermittent Preventive Treatment With Sulfadoxine-Pyrimethamine: A Multicenter (The Gambia, Burkina Faso, and Benin) Cluster-randomized Controlled Trial

Clinical Infectious Diseases, 2018
Adding community-based scheduled malaria screening and treatment to existing intermittent preventive treatment with sulfadoxine-pyrimethamine (IPTp-SP) strategies did not reduce malaria in pregnancy.
Susana Umberto Lindsay John Kalifa Simon Fanta Halidou Ma Scott D’Alessandro Kendall Bradley Bojang Correa N, S. Scott, U. d’Alessandro, L. Kendall, J. Bradley, K. Bojang, Simon Correa, F. Njie, H. Tinto, M. Traoré-Coulibaly, H. M. Natama, O. Traoré, I. Valéa, A. Nahum, Daniel Ahounou, F. Bohissou, G. Sondjo, Carine Agbowai, P. Mens, E. Ruizendaal, H. Schallig, Susan Dierickx, K. P. Grietens, L. Duval, L. Conteh, M. Drabo, J. Guth, F. Pagnoni   +27 more
semanticscholar   +1 more source

Methylene blue inhibits lumefantrine-resistant Plasmodium berghei

Journal of Infection in Developing Countries, 2016
Introduction: Chemotherapy still is the most effective way to control malaria, a major public health problem in sub-Saharan Africa. The large-scale use of the combination therapy artemether-lumefantrine for malaria treatment in Africa predisposes ...
Victor Irungu Mwangi, Ruth Mwende Mumo, Daniel Muthui Kiboi, Sabah Ahmed Omar, Zipporah Waithera Ng'ang'a, Hastings Suba Ozwara   +5 more
doaj   +1 more source