Results 51 to 60 of about 42,597 (297)

Efficacy of chloroquine, sulphadoxine-pyrimethamine and amodiaquine for treatment of uncomplicated Plasmodium falciparum malaria in Kajo Keji county, Sudan. [PDF]

, 2004
To provide advice on the rational use of antimalarial drugs, Médecins Sans Frontières conducted a randomized, an open label efficacy study in Kajo Keji, an area of high transmission of malaria in southern Sudan.
Epicentre, Krishna S, Kshirsagar NA, National Malaria Administration/Unicef, Ochong EO, Omari AA, Seidlein L, UN/OCHA, Vugt M, WHO, WHO, WHO, WHO, WHO/Roll Back Malaria   +13 more
core   +2 more sources

Prevalence of Plasmodium falciparum parasites resistant to sulfadoxine/pyrimethamine in the Democratic Republic of the Congo: emergence of highly resistant pfdhfr/pfdhps alleles

Journal of Antimicrobial Chemotherapy, 2018
Background In 2005, the Democratic Republic of the Congo (DRC) switched to artesunate/amodiaquine as the first-line antimalarial in response to increasing sulfadoxine/pyrimethamine resistance and adopted intermittent preventive treatment using ...
P. Nkoli Mandoko, Florent Rouvier, Lebon Matendo Kakina, D. Moke Mbongi, Christine Latour, J. Losimba Likwela, D. Ngoyi Mumba, S. K. Bi Shamamba, Jean-Jacques Tamfum Muyembe, L. Muepu Tshilolo, D. Parzy, V. Sinou   +11 more
semanticscholar   +1 more source

Audit of failure rate of sulfadoxine/pyrimetham combined with chloroquine to treat falciparum malaria at single fourteen-day follow-up

South African Family Practice, 2002
Objective: To assess the failure rate of the present first line treatment regime for uncomplicated falciparum malaria of sulfadoxine/pyrimethamine combined with chloroquine. Design: A before-after study. Setting: Ndumo Clinic, Ingwavuma District, South
C.H. Vaughan Williams, C. La Cock, G.F.J. Henry, A.J. Ross   +3 more
doaj   +1 more source

Potentiating effect of pyrimethamine and sulfadoxine against dihydrofolate reductase from pyrimethamine-sensitive and pyrimethamine-resistant Plasmodium chabaudi

Antimicrobial Agents and Chemotherapy, 1986
Dihydrofolate reductase was partially purified from a pyrimethamine-sensitive Plasmodium chabaudi clone and a pyrimethamine-resistant clone derived from it and used in a study of the inhibitory effect of pyrimethamine and sulfadoxine, both alone and in combination.
Worachart Sirawaraporn, Yongyuth Yuthavong   +1 more
openaire   +4 more sources

In Vitro Inhibitory Activity of Corilagin and Punicalagin Against Toxoplasma gondii and Their Mechanism(s) of Action

Antibiotics
Background/Objectives: Toxoplasmosis is a zoonotic disease caused by Toxoplasma gondii. The parasite infection in humans continues to rise due to an increasing seroprevalence rate in domestic and wild warm-blooded animals that serve as a major reservoir ...
Nicole T. Green-Ross, Homa Nath Sharma, Audrey Napier, Boakai K. Robertson, Robert L. Green, Daniel A. Abugri   +5 more
doaj   +1 more source

Effects of pyrimethamine-sulphadoxine, chloroquine plus chlorpheniramine, and amodiaquine plus pyrimethamine-sulphadoxine on gametocytes during and after treatment of acute, uncomplicated malaria in children

Memorias do Instituto Oswaldo Cruz, 2006
The effects of pyrimethamine-sulphadoxine (PS), chloroquine plus chlorpheniramine, a H1 receptor antagonist that reverses chloroquine resistance in Plasmodium falciparum in vitro and in vivo (CQCP), and amodiaquine plus pyrimethamine-sulphadoxine (AQPS ...
A Sowunmi, AA Adedeji, GO Gbotosho, BA Fateye, TC Happi   +4 more
doaj   +1 more source

Intermittent preventive treatment of malaria provides substantial protection against malaria in children already protected by an insecticide-treated bednet in Burkina Faso: a randomised, double-blind, placebo-controlled trial. [PDF]

, 2011
BACKGROUND: Intermittent preventive treatment of malaria in children (IPTc) is a promising new approach to the control of malaria in areas of seasonal malaria transmission but it is not known if IPTc adds to the protection provided by an insecticide ...
Chandramohan, Daniel, Cousens, Simon, Diallo, Diadier A, Diarra, Amidou, Gansané, Adama, Greenwood, Brian, Kaboré, Youssouf, Kangoyé, David T, Konaté, Amadou T, Milligan, Paul J, Ouédraogo, Alphonse, Ouédraogo, Amidou Z, Ouédraogo, Espérance, Ouédraogo, Issa N, Sirima, Sodiomon B, Soulama, Issiaka, Tiono, Alfred B, Yaro, Jean Baptiste   +17 more
core   +3 more sources

Population Pharmacokinetic Properties of Sulfadoxine and Pyrimethamine: a Pooled Analysis To Inform Optimal Dosing in African Children with Uncomplicated Malaria

Antimicrobial Agents and Chemotherapy, 2018
Sulfadoxine-pyrimethamine with amodiaquine is recommended by the World Health Organization as seasonal malaria chemoprevention for children aged 3 to 59 months in the sub-Sahel regions of Africa.
M. de Kock, J. Tarning, L. Workman, E. Allen, Mamadou M. Tékété, A. Djimde, D. Bell, S. Ward, K. Barnes, P. Denti   +9 more
semanticscholar   +1 more source

Gametocytaemia in senegalese children with uncomplicated Falciparum malaria treated with chloroquine, amodiaquine or sulfadoxine + pyrimethamine

Parasite, 2001
Plasmodium falciparum gametocytaemia was studied in 266 Senegalese children (median 4 years, range 0.5-16) with uncomplicated malaria treated with chloroquine (CQ), amodiaquine (AQ) or sulfadoxine+pyrimethamine (SP).
Sokhina C.S, Trape J.-F, Robert V.
doaj   +1 more source

Review of pyronaridine anti-malarial properties and product characteristics. [PDF]

, 2012
Pyronaridine was synthesized in 1970 at the Institute of Chinese Parasitic Disease and has been used in China for over 30 years for the treatment of malaria.
Arbe-Barnes, Sarah J, Borghini-Fuhrer, Isabelle, Craft, J Carl, Croft, Simon L, Duparc, Stephan, Fleckenstein, Lawrence, Rim, Han-Jong, Shin, Chang-Sik   +7 more
core   +2 more sources