Results 11 to 20 of about 151,536 (281)
Molecules, 2020 This work demonstrates synthetic strategies for the incorporation of a synthesized pyrimidine glucagon-like peptide-1 (GLP-1) agonist into alginate-coated ZIF-8.
Shaikha S. AlNeyadi +6 more
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Chemical Insights Into the Synthetic Chemistry of Quinazolines: Recent Advances
Frontiers in Chemistry, 2021 In medicinal chemistry, one of the most significant heterocyclic compounds are quinazolines, possessing broad range of biological properties such as anti-bacterial, anti-fungal, anti-HIV, anti-cancer, anti-inflammatory, and analgesic potencies.
Muhammad Faisal, Aamer Saeed
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tert-Butyl 4-{3-[6-(4-methoxyphenyl)-2-methylpyrimidin-4-yl]quinolin-2-yl}piperazine-1-carboxylate
IUCrData, 2018 The asymmetric unit of the title compound, C30H33N5O3, contains two independent molecules, A and B. In molecule A, the tert-butyl 4-methylpiperazine-1-carboxylate group was refined as disordered over two sets of sites with an occupancy ratio of 0.821 (4):
Sumati Anthal +6 more
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Pyrimidine biosynthesis is not an essential function for Trypanosoma brucei bloodstream forms.
PLoS ONE, 2013 BackgroundAfrican trypanosomes are capable of both pyrimidine biosynthesis and salvage of preformed pyrimidines from the host, but it is unknown whether either process is essential to the parasite.Methodology/principal findingsPyrimidine requirements for
Juma A M Ali +5 more
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2-Amino-5-methyl-1,2,4-triazolo[1,5-a]pyrimidin-7(4H)-one
IUCrData, 2018 The asymmetric unit of the title compound, C6H7N5O, consists of two molecules with almost identical conformations. In the crystal, inversion dimers linked by pairs of N—H...N hydrogen bonds occur for both molecules; further N—H...N and N—H...O hydrogen ...
Sanae Lahmidi +5 more
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Purine and pyrimidine nucleotide metabolism in Mollicutes
Genetics and Molecular Biology, 2007 Several mollicute genome projects are underway, offering unique opportunities to study genes and metabolic pathways on a genome-wide scale. Here, we have analyzed the conservation and diversity of purine and pyrimidine metabolism in mycoplasmas.
Cristiano Valim Bizarro +1 more
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1-Methyl-3-(2-methylphenyl)-4-phenyl-1H-pyrazolo[3,4-d]pyrimidine
IUCrData, 2017 In the title compound, C19H16N4, the pyrazolopyrimidine unit is slightly twisted. A combination of π-stacking and offset π-stacking interactions forms columns along the b-axis direction.
Mohamed El Hafi +5 more
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4-amino-2-phenyl-6-(p-fluorophenyl)-5-carbonitrile-pyrimidine-bis-substituted-loaded liposomes as promising system for cancer treatment [PDF]
Anais da Academia Brasileira de Ciências, 2023 The aim of the present study was to perform in vitro and in vivo assessments of the antineoplastic action of 4-amino-pyrimidine encapsulated in liposomes. Liposomes were prepared and characterized for particle size and drug encapsulation and submitted to
JANICE V. OLIVEIRA +9 more
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In Plane Vibration of Pyrimidine and some Deuterated Pyrimidines [PDF]
Iranian Journal of Chemistry & Chemical Engineering, 1991 On the basis of 102 assigned frequencies to in plane vibrations of pyrimidine, pyrimidine-2-d2, pyrimidine-2, 5-d2, pyrimidine-4,6-d2, pyrimidine-2,4,6-d3 and pyrimidine-d4, 35 valance force field constants including 14 principals and 21 interaction ...
F. Milani Nejad,
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Frontiers in Cellular and Infection Microbiology, 2018 Cytidine triphosphate synthase catalyzes the synthesis of cytidine 5′-triphosphate (CTP) from uridine 5′-triphosphate (UTP), the final step in the production of cytidine nucleotides.
Heidy Y. Narvaez-Ortiz +3 more
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