Results 241 to 250 of about 290,598 (376)

A prebiotically plausible synthesis of pyrimidine β-ribonucleosides and their phosphate derivatives involving photoanomerization.

Nature Chemistry, 2017
Jianfeng Xu, Maria Tsanakopoulou, Christopher J. Magnani, Rafał Szabla, J. Šponer, J. Šponer, R. Góra, J. Sutherland   +7 more
semanticscholar   +1 more source

Purine Chemistry in the Early RNA World at the Origins of Life: From RNA and Nucleobases Lesions to Current Key Metabolic Routes. [PDF]

Chembiochem
Décout JL, Maurel MC.
europepmc   +1 more source

The Impact of the Rs1044457 Polymorphism in the CMPK1 Gene on the Response Rate to Gemcitabine‐Based Chemotherapy in Metastatic NSCLC Patients

Advanced Genetics, EarlyView.
Lung cancer is the leading cause of cancer‐related mortality worldwide. Among its types, non‐small cell lung cancer (NSCLC) accounts for the majority of cases. This study focuses on investigating genetic mutations that may influence the response to gemcitabine, a chemotherapy drug commonly used to treat this condition.
Ghassan Saod Saleh, Fouad Kadhim Gatea, Qasim Sharhan Al‐Mayah, Hayder Lazim   +3 more
wiley   +1 more source

The Utilization of Exogenous Pyrimidines and the Recycling of Uridine‐5′‐Phosphate Derivatives in Saccharomyces cerevisiae, as Studied by Means of Mutants Affected in Pyrimidine Uptake and Metabolism [PDF]

, 1969
Marcelle Grenson
openalex   +1 more source

Exploring Aspartate Transcarbamoylase: A Promising Broad-Spectrum Target for Drug Development. [PDF]

Chembiochem
Chen S, Mondile Q, Du X, Wang C, Mukim M, Wrenger C, Dömling ASS, Tastan Bishop Ö, Groves MR.   +8 more
europepmc   +1 more source

Association between prediagnostic serum metabolites and pancreatic ductal adenocarcinoma risk in two prospective cohorts

International Journal of Cancer, EarlyView.
What's New? Exposures and mechanisms that contribute to and promote pancreatic ductal adenocarcinoma (PDAC) remain unclear. In this study, the authors applied metabolomics to better understand PDAC etiology by examining associations between prediagnostic serum metabolites and PDAC risk.
Ting Zhang, Steven C. Moore, Sheng Fu, Xiaoyu Wang, Demetrius Albanes, Stephanie J. Weinstein, Kai Yu, Rachael Z. Stolzenberg‐Solomon   +7 more
wiley   +1 more source

The Origin of Purine and Pyrimidine Deoxyribose in Escherichia coli Systems

, 1959
Marilyn R. Loeb, Seymour S. Cohen
openalex   +1 more source

Antimicrobial activity, synthesis, and docking study of some novel arylazo-1,3-thiazolopyrimidine and arylazo-1,3-thiazolopyridopyrimidine derivatives. [PDF]

BMC Chem
Qurban J, Alqarni SA, Alalawy AI, Alshammari NAH, Ashour GRS, Alnoman MM, Katuah HA, El-Metwaly NM.   +7 more
europepmc   +1 more source

Temporal response patterns of human gut microbiota to dietary fiber

iMeta, EarlyView.
In this study, 19 overweight participants, with or without type 2 diabetes mellitus, underwent 14 days of normal‐diet observation followed by 14 days of dietary fiber intervention. Fecal samples and continuous glucose monitoring data were collected daily throughout the 28‐day period.
Xiaotong Lin, Chaoxun Wang, Biao Liu, Yin Zhu, Rui Zhai, Chenhong Zhang   +5 more
wiley   +1 more source

Studies on the control of pyrimidine biosynthesis in human diploid cell strains, I. Effect of 6-azauridine on cellular phenotype. [PDF]

, 1967
L. Pinsky, Robert S. Krooth
openalex   +1 more source