Results 221 to 230 of about 161,675 (297)

Therapeutic effect of NEO400, perillyl alcohol conjugated to linoleic acid, in a mouse model of UV‐induced skin damage

Photochemistry and Photobiology, Volume 101, Issue 2, Page 338-349, March/April 2025.
In the present work with mouse models, we demonstrate that a novel compound, NEO400, is able to profoundly protect skin against damage caused by UV radiation (UVR) when it is applied to skin post‐UVR exposure. In comparison, Aloe vera or linoleic acid are unable to achieve a similar level of protection.
Stephen Swenson, Catalina Silva‐Hirschberg, Liliana Freeland, Kristen L. Chen, Nagore I. Marín‐Ramos, Axel H. Schönthal, Thomas C. Chen   +6 more
wiley   +1 more source

Contribution of One-Electron Oxidation of Purine and Pyrimidine Bases to the Photo- and Radiation-Induced Damage to Cellular DNA. [PDF]

Chemphyschem
Cadet J, Angelov D, DI Mascio P, Wagner JR.   +3 more
europepmc   +1 more source

Interventional human ocular safety experiments for 222‐nm far‐ultraviolet‐C lamp irradiation

Photochemistry and Photobiology, Volume 101, Issue 2, Page 517-526, March/April 2025.
To directly assess the ocular safety of 222‐nm far‐ultraviolet‐C (UVC) irradiation in humans, five subjects were exposed to 222‐nm UVC at doses of 22, 50, and 75 mJ/cm2. The findings indicate that far‐UVC irradiation does not cause “clinically significant photokeratitis” or long‐term ocular damage, though it may induce temporary discomfort.
Kazunobu Sugihara, Sachiko Kaidzu, Masahiro Sasaki, Masaki Tanito   +3 more
wiley   +1 more source

Mitophagy-Competent Cancer-Associated Fibroblasts Fuel Chemoresistance by Rewiring Pyrimidine Metabolism in Pancreatic Cancer. [PDF]

Cancer Res
Zhang S, Yuan H, Guo M, Zhou Z, Hu Y, Lv G, Qi H, Guo Y, Han J, Bronze MS, Houchen CW, Li M, Liu M.   +12 more
europepmc   +1 more source

Photoprotective potential of gadusol against ultraviolet B radiation in melanocytes

Photochemistry and Photobiology, EarlyView.
Gadusol protects melanocytes from ultraviolet B (UVB)‐induced damage without cytotoxicity. Abstract The increasing incidence of skin cancer, including melanoma, combined with the need for ultraviolet (UV) filters that are safe for human health and marine ecosystems, is driving the search for new photoprotective agents.
Andressa Mai Matsumoto, Rocío Isla Naveira, Andy Joel Taipe Huisa, Marcelo Augusto Germani Marinho, Lais Zortéa, José María Monserrat, Agueda Elena Massa, María Sandra Churio, Ana Paula de Souza Votto   +8 more
wiley   +1 more source

Discovery of Novel Small-Molecule Toll-like Receptor 2 Agonists via a Scaffold Hopping Strategy. [PDF]

ACS Med Chem Lett
Zhu Y, Wang L, Chen Y, Wang Y, Chen Z, Li Y, Zhang W.   +6 more
europepmc   +1 more source

Novel Trifluoromethyl-Substituted Dipyrimidinamine Derivatives as Potential Antifungal Agents for Controlling Postharvest Soft Rot in Kiwifruit. [PDF]

J Fungi (Basel)
Wu W, Zhao J, Geng P, Fei Q, Chen H.
europepmc   +1 more source

Selected Thieno[2,3-<i>d</i>] Pyrimidine Derivatives Target Breast Cancer Cell Proliferation and Membrane Organization. [PDF]

Molecules
Nesheva A, Iliev I, Mavrova A, Yancheva D, Kostadinova A, Semkova S, Momchilova A, Tsoneva I, Nikolova B, Staneva G.   +9 more
europepmc   +1 more source

Bioinspired NiCoO₂ nanocomposites derived from Moringa oleifera as a recyclable catalyst for the synthesis of pyrazolopyrano[2,3-d]pyrimidine with potent antimicrobial efficiency. [PDF]

Discov Nano
Kokare P, Kadam A, More A, Shinde V, Ghanwat V, Pandit N, Bagade C, Survase A, Mali K, Kamble S.   +9 more
europepmc   +1 more source