Results 241 to 250 of about 251,884 (333)

Fused pyrimidines. V. Synthesis of 2-aminopyrimido[4,5-e]-1,3,4-thiadiazine and some related compounds from 6-thiosemicarbazidouracils.

, 1979
Takehiko Naka, Yoshiyasu Furukawa
openalex   +2 more sources

RAD51 and RAD51 paralog inhibition sensitizes nonreplicating quiescent keratinocytes to UV radiation

Photochemistry and Photobiology, EarlyView.
UV radiation and other compounds generate DNA adducts that block transcription and induce cell death if not removed by the nucleotide excision repair system. In this work, we used a small‐scale pharmacological screen to discover that inhibition of the recombinase RAD51 sensitized nonreplicating quiescent keratinocytes to both UVR and other agents that ...
Saman Khan, Angitha Nair, M. Alexandra Carpenter, Michael G. Kemp   +3 more
wiley   +1 more source

Rational synthesis of pyrazolopyrimidines <i>via</i> cyclocondensation of ynones obtained from the Sonogashira reaction. [PDF]

RSC Adv
Bhagat S, Goel N, Kumari P, Kumar P.
europepmc   +1 more source

Photoprotective potential of gadusol against ultraviolet B radiation in melanocytes

Photochemistry and Photobiology, EarlyView.
Gadusol protects melanocytes from ultraviolet B (UVB)‐induced damage without cytotoxicity. Abstract The increasing incidence of skin cancer, including melanoma, combined with the need for ultraviolet (UV) filters that are safe for human health and marine ecosystems, is driving the search for new photoprotective agents.
Andressa Mai Matsumoto, Rocío Isla Naveira, Andy Joel Taipe Huisa, Marcelo Augusto Germani Marinho, Lais Zortéa, José María Monserrat, Agueda Elena Massa, María Sandra Churio, Ana Paula de Souza Votto   +8 more
wiley   +1 more source

Metabolic Dependency on De Novo Pyrimidine Synthesis Is a Targetable Vulnerability in Platinum-Resistant Ovarian Cancer. [PDF]

Cancer Res
Cardenas H, Wang Y, Zhao G, Hao DX, Isac AM, Hernandez V, Kim U, Qiang W, Zhang HF, Matei D.   +9 more
europepmc   +1 more source

Advances in organic UV filters for sunscreens over the past decade

Photochemistry and Photobiology, EarlyView.
Highlighted organic UV filter frameworks that have been described for sunscreens over the past decade divided into three groups: derivatives of or inspired by approved organic UV filters, natural product‐based compounds, and miscellaneous. Abstract Ultraviolet (UV) radiation is a major environmental factor in photoaging, erythema, and skin cancer ...
Gabriela Zanella Marcon, Maria Carolina Theisen, Andressa Motta Castro, Giovana Jones Radke, Fernando Fumagalli   +4 more
wiley   +1 more source

Discovery of [1,2,4]triazolo[1,5-a]pyrimidine-Imatinib Hybrids With Selective Cytotoxic Activity: A Mechanistically Divergent Series From Direct BCR-ABL1 Inhibition. [PDF]

ChemMedChem
Moura SCB, de Oliveira AP, Neto JMR, Dantas RF, Silva-Jr FP, Pimentel LC, Carvalho MSDN, Leite DI, da Silva DV, Bastos MM, Boechat N.   +10 more
europepmc   +1 more source

Studies on pyrimidine derivatives. XXXIV. Substituent effect on the reaction of 4-substituted 2,6-dimethylpyrimidine 1-oxides with acetic anhydride.

, 1984
Takao Sakamoto, Hiroshi Yoshizawa, S. KANEDA, Hiroshi Yamanaka   +3 more
openalex   +2 more sources

Chemical agents to control biofilm formation in step 1 of care—Toothpastes and mouthwashes/concepts and challenges

Periodontology 2000, EarlyView.
Abstract Maintaining optimal oral hygiene is important for overall oral care, ensuring the well‐being of teeth and their surrounding tissues. In addition, it promotes fresh breath and a pleasing smile. A key element of oral self‐care is the daily use of toothpaste during regular brushing.
Maud Joosstens, Cees Valkenburg, Fridus Van der Weijden   +2 more
wiley   +1 more source