Results 231 to 240 of about 161,675 (297)

Role of <i>Toxoplasma gondii</i> calcium-binding protein (<i>Tg</i>pCaBP) and its implications for the development of attenuated live vaccines. [PDF]

Microbiol Spectr
Zhang Y, Li H, Jing Y, Sun W, Wei B, Wei Z, Jiang N.   +6 more
europepmc   +1 more source

Privileged nitrogen heterocycles in anticancer drug discovery: recent advances on imidazole, indole, and pyrimidine scaffolds. [PDF]

RSC Adv
Govindarajan M, Maji L, Mannathan S, Kumaradoss KM, Chowdhury A, Jois SD, Baskar B.   +6 more
europepmc   +1 more source

Pyrimidine derivatives with antitubercular activity [PDF]

European Journal of Medicinal Chemistry, 2023
Small molecules with antitubercular activity containing the pyrimidine motif in their structure have gained more attention after three drugs, namely GSK 2556286 (GSK-286), TBA-7371 and SPR720, have entered clinical trials.
Ondrej Soukup, Jan Korábečný, Vladimir Finger   +2 more
exaly   +2 more sources

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Pyrimidines. XIII. Novel pyrimidine to pyrimidine transformation reactions

Journal of Heterocyclic Chemistry, 1977
AbstractNovel pyrimidine to pyrimidine transformation reactions are described. 1,3‐Dimethyl‐(or diethyl)‐uracil(1) are converted into isocytosine, 2‐thiouracil or uracil derivatives by treatment with guanidine, thiourea or urea, respectively. The latter two cases require base catalysis. The effects of some substituents at C‐5 and C‐6 of 1,3‐dialkylated
Kosaku Hirota, Kyoichi A. Watanabe, Jack J. Fox   +2 more
openaire   +1 more source

The Auger spectroscopy of pyrimidine and halogen-substituted pyrimidines

The Journal of Chemical Physics, 2008
The C 1s and N 1s Auger spectra of pyrimidine, 2-chloropyrimidine, and 5-bromopyrimidine have been measured in an electron impact experiment at 1000 eV. In the case of the halogen-substituted pyrimidines, also the Cl 2p and Br 3d Auger spectra have been recorded.
Storchi L, Tarantelli F, Veronesi S, Bolognesi P, Fainelli E, Avaldi L   +5 more
openaire   +3 more sources

ChemInform Abstract: PYRIMIDINES. XIII. NOVEL PYRIMIDINE TO PYRIMIDINE TRANSFORMATION REACTIONS

Chemischer Informationsdienst, 1977
AbstractBei der Behandlung mit Guanidin (II) erhält man aus 1,3‐Dimethyluracil sowie den . analogen Verbindungen (I) die Pyrimidinone (III).
K. HIROTA, K. A. WATANABE, J. J. FOX
openaire   +1 more source

Anticancer pyrimidines, pyrimidine nucleosides and prodrugs

1990
Of the plethora of pyrimidines, pyrimidine nucleosides, analogues and prodrug derivatives that have been synthesised and evaluated as anticancer agents, only two are in general clinical use. The long-studied 5-fluorouracil (5-FUra (1), see Scheme 9.1), and some nucleoside and prodrug derivatives, are used regularly for the treatment of breast cancer ...
M. MacCoss, M. J. Robins
openaire   +1 more source

Pyrimidines. VIII. Pyrimidine Derivatives of Thioguanine

Journal of Medicinal and Pharmaceutical Chemistry, 1962
H C, KOPPEL, R H, SPRINGER, R K, ROBINS, C C, CHENG   +3 more
openaire   +2 more sources

Pyrimidine phototetramer

Journal of the American Chemical Society, 1971
S Y, Wang, D F, Rhoades
openaire   +2 more sources