Molecules, 2020 This work demonstrates synthetic strategies for the incorporation of a synthesized pyrimidine glucagon-like peptide-1 (GLP-1) agonist into alginate-coated ZIF-8.
Shaikha S. AlNeyadi +6 more
doaj +1 more source
Phosphorylation of purine and pyrimidine nucleosides by isolated rat liver mitochondria [PDF]
, 1975 Formation of 5'-AMP, 5'-GMP, 5'-CMP and 5'UMP was confirmed in isolated rat liver mitochondria incubated with alpha-ketoglutarate, inorganic phosphate, purine nucleoside and pyrimidine nucleoside. Increased incorporation of 32Pi into ATP, GTP and UTP was
Inaba, Kozo, Oda, Takuzo
core +1 more source
Chemical Insights Into the Synthetic Chemistry of Quinazolines: Recent Advances
Frontiers in Chemistry, 2021 In medicinal chemistry, one of the most significant heterocyclic compounds are quinazolines, possessing broad range of biological properties such as anti-bacterial, anti-fungal, anti-HIV, anti-cancer, anti-inflammatory, and analgesic potencies.
Muhammad Faisal, Aamer Saeed
doaj +1 more source
Synthesis and coordination chemistry of 2-(di-2-pyridylamino)pyrimidine; structural aspects of spin crossover in an Fe(II) complex [PDF]
, 2012 This paper was accepted on February 26 20122-(Di-2-pyridylamino)pyrimidine (L), a potentially ditopic tetradentate ligand, was synthesized from commercially available di-2-pyridylamine and 2-chloropyrimidine.
Addison +38 more
core +2 more sources
ACS Omega, 2021 A class of pyrimidine thioglycoside analogs (6a–h) were synthesized from a reaction of 2-cyano-3,3-dimercapto-N-arylacrylamide (2a–d) and thiourea to produce the corresponding 4-amino-2-mercapto-N-arylpyrimidine-5-carboxamide derivatives (3a–d), and ...
M. Abu-Zaied, G. Elgemeie, N. Mahmoud
semanticscholar +1 more source
tert-Butyl 4-{3-[6-(4-methoxyphenyl)-2-methylpyrimidin-4-yl]quinolin-2-yl}piperazine-1-carboxylate
IUCrData, 2018 The asymmetric unit of the title compound, C30H33N5O3, contains two independent molecules, A and B. In molecule A, the tert-butyl 4-methylpiperazine-1-carboxylate group was refined as disordered over two sets of sites with an occupancy ratio of 0.821 (4):
Sumati Anthal +6 more
doaj +1 more source
The Effects of Ultraviolet Light on Anthocyanin Accumulation in the Adventitious Roots of Sedum wrightii (Crassulaceae) [PDF]
, 2018 Several studies have supported the idea that anthocyanin accumulation may be a possible protection mechanism in plants against DNA damage caused by ultraviolet radiation (UV).
Gravatt, Dennis A. +2 more
core +2 more sources
2-Amino-5-methyl-1,2,4-triazolo[1,5-a]pyrimidin-7(4H)-one
IUCrData, 2018 The asymmetric unit of the title compound, C6H7N5O, consists of two molecules with almost identical conformations. In the crystal, inversion dimers linked by pairs of N—H...N hydrogen bonds occur for both molecules; further N—H...N and N—H...O hydrogen ...
Sanae Lahmidi +5 more
doaj +1 more source
Rational Design, Synthesis and Biological Evaluation of Pyrimidine-4,6-diamine derivatives as Type-II inhibitors of FLT3 Selective Against c-KIT. [PDF]
, 2018 FMS-like Tyrosine Kinase 3 (FLT3) is a clinically validated target for acute myeloid leukemia (AML). Inhibitors targeting FLT3 have been evaluated in clinical studies and have exhibited potential to treat FLT3-driven AML.
Bharate, Jaideep B +8 more
core +2 more sources
Purine and pyrimidine nucleotide metabolism in Mollicutes
Genetics and Molecular Biology, 2007 Several mollicute genome projects are underway, offering unique opportunities to study genes and metabolic pathways on a genome-wide scale. Here, we have analyzed the conservation and diversity of purine and pyrimidine metabolism in mycoplasmas.
Cristiano Valim Bizarro +1 more
doaj +1 more source