Results 291 to 300 of about 290,598 (376)

The continuing significance of chiral agrochemicals

open access: yesPest Management Science, Volume 81, Issue 4, Page 1697-1716, April 2025.
In the time frame 2018–2023, around 43% of the 35 chiral agrochemicals introduced to the market (herbicides, fungicides, insecticides, acaricides, and nematicides) contain one or more stereogenic centers in the molecule, and almost 69% of them have been marketed as racemic mixtures of enantiomers or stereoisomers.
Peter Jeschke
wiley   +1 more source

Design, synthesis, <i>in silico</i> studies and antiproliferative evaluation of some novel hybrids of pyrimidine-morpholine. [PDF]

open access: yesFront Chem
Ataollahi E   +9 more
europepmc   +1 more source

Influence of Cosolvents on the Pressure Stability of Human Serum Albumin

open access: yesphysica status solidi (a), EarlyView.
Human serum albumin is able to bind various hydrophobic substances and drugs. To investigate this interaction, the protein structure is analyzed using small‐angle X‐ray scattering under high hydrostatic pressure. The resulting radius of gyration (see picture) indicates that hydrophobic substances influence the pressure stability of HSA differently ...
Jaqueline Savelkouls   +3 more
wiley   +1 more source

Fluorescent Antibiotics: Bridging Diagnostic and Therapy in the Fight against Bacterial Infections

open access: yesSmall Science, EarlyView.
This review critically evaluates fluorescent antibiotics as promising agents combining diagnostic precision with therapeutic efficacy. It highlights advances in probe design, chemical conjugation strategies, real‐time imaging applications, selective pathogen detection, and targeted therapy. The potential to combat antimicrobial resistance is discussed,
Tan Phuoc Ton   +3 more
wiley   +1 more source

Pyrimidine Nucleosidases

open access: hybrid, 1965
Thomas A. Krenitsky   +2 more
openalex   +1 more source

Nanozymes in Reactive Oxygen Species‐Dependent Diseases: From Design and Preclinical Studies to Clinical Translation Prospects

open access: yesSmall Structures, EarlyView.
Nanozymes emerge as promising therapeutic agents for reactive oxygen species (ROS)‐dependent diseases, offering advantages over traditional biocatalysts through enhanced stability, tunability, and targeting capabilities. This review explores their mechanisms, design strategies, and clinical progress, emphasizing precision medicine potential.
Lihong Zhou   +8 more
wiley   +1 more source

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