Results 31 to 40 of about 319,341 (367)

The Ability of Cyanobacterial Cells to Restore UV-B Radiation Induced Damage to Photosystem II is Influenced by Photolyase Dependent DNA Repair [PDF]

, 2013
Damage of DNA and Photosystem-II are among the most significant effects of UV-B irradiation in photosynthetic organisms. Both damaged DNA and Photosystem-II can be repaired, which represent important defense mechanisms against detrimental UV-B effects ...
Kós, Péter, Nagy, Csaba István, Sass, László, Vass, Imre, Vass, István-Zoltán   +4 more
core   +1 more source

Bimetallic Pt(II)-bipyridyl-diacetylide/Ln(III) tris-diketonate adducts based on a combination of coordinate bonding and hydrogen bonding between the metal fragments: syntheses, structures and photophysical properties [PDF]

, 2009
The luminescent Pt(II) complex [Pt(4,4'-Bu-t(2)-bipy){CC-(5-pyrimidinyl)}(2)] (1) was prepared by coupling of [Pt(4,4'-Bu-t(2)-bipy)Cl-2] with 5-ethynyl-pyrimidine, and contains two pyrimidinyl units pendant from a Pt(H) bipyridyl diacetylide core; it ...
Beeby, Beeby, Beer, Daniel Sykes, Glover, Hasegawa, Hissler, James, Klink, Lazarides, Lazarides, McCleverty, Mehlstäubl, Michael D. Ward, Nawal K. Al-Rasbi, Pope, Reeves, Ronson, Shavaleev, Shavaleev, Sheldrick, Sheldrick, Sofia Derossi, Stephen Faulkner, Stouwdam, Torelli, Ward, Ward, Whittle, Xu, Yu   +30 more
core   +1 more source

1-Methyl-3-(2-methylphenyl)-4-phenyl-1H-pyrazolo[3,4-d]pyrimidine

IUCrData, 2017
In the title compound, C19H16N4, the pyrazolopyrimidine unit is slightly twisted. A combination of π-stacking and offset π-stacking interactions forms columns along the b-axis direction.
Mohamed El Hafi, Mohammed Boulhaoua, Youssef Ramli, Mohammed Benchidmi, El Mokhtar Essassi, Joel T. Mague   +5 more
doaj   +1 more source

Unified prebiotically plausible synthesis of pyrimidine and purine RNA ribonucleotides

Science, 2019
Conditions right for making nucleosides In the absence of biological catalysts and metabolism, can atmospheric and geochemical processes provide the substrates and conditions required for production of biological molecules? Becker et al.
S. Becker, Jonas Feldmann, Stefan Wiedemann, Hidenori Okamura, Christina Schneider, K. Iwan, Antony L. Crisp, M. Rossa, Tynchtyk Amatov, T. Carell   +9 more
semanticscholar   +1 more source

Decitabine- and 5-azacytidine resistance emerges from adaptive responses of the pyrimidine metabolism network

Leukemia, 2020
Mechanisms-of-resistance to decitabine and 5-azacytidine, mainstay treatments for myeloid malignancies, require investigation and countermeasures. Both are nucleoside analog pro-drugs processed by pyrimidine metabolism into a deoxynucleotide analog that ...
X. Gu, R. Tohme, B. Tomlinson, Nneha Sakre, M. Hasipek, Lisa Durkin, Caroline Schuerger, D. Grabowski, Asmaa M. Zidan, T. Radivoyevitch, Changjin Hong, H. Carraway, B. Hamilton, R. Sobecks, B. Patel, B. Jha, E. Hsi, J. Maciejewski, Y. Saunthararajah   +18 more
semanticscholar   +1 more source

4-amino-2-phenyl-6-(p-fluorophenyl)-5-carbonitrile-pyrimidine-bis-substituted-loaded liposomes as promising system for cancer treatment [PDF]

Anais da Academia Brasileira de Ciências, 2023
The aim of the present study was to perform in vitro and in vivo assessments of the antineoplastic action of 4-amino-pyrimidine encapsulated in liposomes. Liposomes were prepared and characterized for particle size and drug encapsulation and submitted to
JANICE V. OLIVEIRA, GLEYBSON C. ALMEIDA, MARIANE C.B.L. NOGUEIRA, FRANCISCO C.A. AGUIAR JÚNIOR, AUDENES O. MELO, THIAGO D.S. SILVA, NOEMIA P.S. SANTOS, NEREIDE S.S. MAGALHÃES, SEBASTIÃO J. MELO, EMERSON P.S. FALCÃO   +9 more
doaj   +1 more source

In Plane Vibration of Pyrimidine and some Deuterated Pyrimidines [PDF]

Iranian Journal of Chemistry & Chemical Engineering, 1991
On the basis of 102 assigned frequencies to in plane vibrations of pyrimidine, pyrimidine-2-d2, pyrimidine-2, 5-d2, pyrimidine-4,6-d2, pyrimidine-2,4,6-d3 and pyrimidine-d4, 35 valance force field constants including 14 principals and 21 interaction ...
F. Milani Nejad,
doaj  

A CTP Synthase Undergoing Stage-Specific Spatial Expression Is Essential for the Survival of the Intracellular Parasite Toxoplasma gondii

Frontiers in Cellular and Infection Microbiology, 2018
Cytidine triphosphate synthase catalyzes the synthesis of cytidine 5′-triphosphate (CTP) from uridine 5′-triphosphate (UTP), the final step in the production of cytidine nucleotides.
Heidy Y. Narvaez-Ortiz, Andrea J. Lopez, Nishith Gupta, Barbara H. Zimmermann   +3 more
doaj   +1 more source

1,2,3-Triazolyl-tetrahydropyrimidine Conjugates as Potential Sterol Carrier Protein-2 Inhibitors: Larvicidal Activity against the Malaria Vector Anopheles arabiensis and In Silico Molecular Docking Study

Molecules, 2022
Alteration of insect growth regulators by the action of inhibitors is becoming an attractive strategy to combat disease-transmitting insects. In the present study, we investigated the larvicidal effect of 1,2,3-triazolyl-pyrimidinone derivatives against ...
Katharigatta N. Venugopala, Pottathil Shinu, Christophe Tratrat, Pran Kishore Deb, Raquel M. Gleiser, Sandeep Chandrashekharappa, Deepak Chopra, Mahesh Attimarad, Anroop B. Nair, Nagaraja Sreeharsha, Fawzi M. Mahomoodally, Michelyne Haroun, Mahmoud Kandeel, Syed Mohammed Basheeruddin Asdaq, Viresh Mohanlall, Nizar A. Al-Shar’i, Mohamed A. Morsy   +16 more
doaj   +1 more source

The Human SLC25A33 and SLC25A36 Genes of Solute Carrier Family 25 Encode Two Mitochondrial Pyrimidine Nucleotide Transporters [PDF]

, 2014
The human genome encodes 53 members of the solute carrier family 25 (SLC25), also called the mitochondrial carrier family, many of which have been shown to transport inorganic anions, amino acids, carboxylates, nucleotides, and coenzymes across the inner
Agrimi, G., Cirigliano, A., Di Noia, M. A., Iacobazzi, V., Palmieri, Ferdinando, Rinaldi, T., Todisco, S.   +6 more
core   +2 more sources