Results 61 to 70 of about 151,536 (281)

OCTN2 Activates a Non‐Canonical Carnitine Metabolic Pathway to Promote MASH‐HCC Progression and Immunotherapy Resistance

Advanced Science, EarlyView.
In non‐MASH‐HCC, L‐carnitine promotes tumor progression primarily through its classical role in enhancing fatty acid oxidation (FAO). However, in MASH‐HCC, where FAO is markedly suppressed, L‐carnitine shifts from this canonical function to serve instead as an intracellular acetyl group buffer.
Chuqi Xia, Xiao Zhang, Jinze Li, Ning Xu, Sheng Hu, Qiyu Lu, Yuxuan Li, Taifu Xiao, Xu Li, Xue Wang, Kequan Xu, Daoming Liang   +11 more
wiley   +1 more source

Novel One-Pot Synthesis of Pyrazolopyranopyrimidinones Using Newly Produced γ-Alumina Nanoparticles as Powerful Catalyst [PDF]

Iranian Journal of Chemistry & Chemical Engineering, 2018
g-Alumina nanoparticles (g-Al2O3 NPs) were prepared via a new and simple synthetic route and characterized by field emission scanning electron microscopy, X-ray diffraction, and Fourier transform infrared spectroscopy.
Sajad Kiani, Saeid Khodabakhshi, Alimorad Rashidi, Ziba Tavakoli, Sadegh Dastkhoon   +4 more
doaj  

The crystal structure of 1-(2-iodobenzoyl)-4-(pyrimidin-2-yl)piperazine: a three-dimensional hydrogen-bonded framework, augmented by π–π stacking interactions and I...N halogen bonds

Acta Crystallographica Section E: Crystallographic Communications, 2019
In 1-(2-iodobenzoyl)-4-(pyrimidin-2-yl)piperazine, C15H15IN4O, the central piperazine ring adopts an almost perfect chair conformation with the pyrimidine substituent in an equatorial site.
Ninganayaka Mahesha, Hemmige S. Yathirajan, Tetsundo Furuya, Takashiro Akitsu, Christopher Glidewell   +4 more
doaj   +1 more source

Acceptor‐Bridged Engineering Enables Highly Efficient Solution‐Processed Pure‐Green MR‐TADF OLEDs With External Quantum Efficiency of 29% and Small Roll‐Off

Advanced Science, EarlyView.
Solution‐processible pure green multi‐resonance thermally activated delayed fluorescence (MR‐TADF) emitters are developed through a strategic acceptor‐bridging engineering approach that integrates MR‐building blocks with pyrimidine‐derived frameworks.
Xuming Zhuang, Qing Zhang, Jinbei Wei, Zhiqiang Li, Baoyan Liang, Chenguang Wang, Hai Bi, Yue Wang, Geyu Lu   +8 more
wiley   +1 more source

Engineering Immune Cell to Counteract Aging and Aging‐Associated Diseases

Advanced Science, EarlyView.
This review highlights a paradigm shift in which advanced immune cell therapies, initially developed for cancer, are now being harnessed to combat aging. By engineering immune cells to selectively clear senescent cells and remodel pro‐inflammatory tissue microenvironments, these strategies offer a novel and powerful approach to delay age‐related ...
Jianhua Guo, Lanjie Lei, Ying Jin, Lan Su, Shumao Cui, Liyun Shi   +5 more
wiley   +1 more source

Sugar‐Armored Pesticides: Self‐Assembled System for Enhanced Foliar Adhesion and Sustained Delivery of Hydrophobic Antimicrobials Against Bacterial Diseases

Advanced Science, EarlyView.
This study develops a sugar‐armored, self‐assembled pesticide delivery system that enhances foliar adhesion, provides sustained release, effectively disrupts biofilms, and demonstrates superior bactericidal activity for improved disease control.
Jinghan Yang, Juan Liu, Xiaohui Wang, Peiyi Wang   +3 more
wiley   +1 more source

Expanding Catch and Release DNA Decoy (CRDD) Technology with Pyrimidine Mimics

, 2022
Samantha A. Kennelly, Ramkumar Moorthy, Ruben Silva Otero, Daniel A. Harki   +3 more
openalex   +1 more source

Synthesis and Antimicrobial Evaluation of Novel Pyrazole, Imidazole and Pyrimidine Derivatives Possessing Imidazo[4,5-b]indol Moiety

Chemistry Journal of Moldova: General, Industrial and Ecological Chemistry, 2019
In this study, novel pyrazole, imidazole, pyrimidine derivatives bearing imidazo[4,5-b]indol moiety were successfully synthesized and their chemical structures were identified and confirmed by different spectral techniques.
Nadia Ali Ahmed Elkanzi, Amira Atef Ghoneim, Hajer Hrichi   +2 more
doaj   +1 more source

Mechanism of Hydrogen Sulfide Generation and Prevention Strategies in Oil and Gas Fields: A Case Study of the Sickle Bay Operation Area

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT To address the persistent exceedance of hydrogen sulfide (H2S) concentrations and the limited effectiveness of existing treatments in the Sickle Bay oil production area, this study deeply analyzes the mechanism of H2S generation in the Sickle Bay oil production area and proposes targeted prevention and control strategies. The results show that
Bo Lei, Yao‐long Li, Bao‐ping Bai, Xiang‐de Zhang, Guan‐tao Shi, Yong‐long Xie, Chen‐xiao Hou, Cong‐Yu Ke   +7 more
wiley   +1 more source

Aromatic Diester Anolytes for Nonaqueous Redox Flow Batteries

Batteries &Supercaps, EarlyView.
Owing to their extended π‐conjugation 2,2′‐bipyridyl aromatic diesters are stable in singly‐ and doubly‐reduced states. In a redox flow battery a high battery voltage of 2.82 V can be realized and a capacity a capacity retention of 99.5% per cycle for 260 cycles.
Nicolas Daub, Dimitar Georgiev, René A. J. Janssen   +2 more
wiley   +1 more source