Results 151 to 160 of about 14,504 (194)

Mechanism of photosensitized dimerization of pyrimidines

Chemical Communications (London), 1968
Excited sensiter molecule in triplet state interacting with the target molecule (thymine) tranfers its triplet state energy to the latter. Two excited target molecule dimerize.
Kornhauser, Andrija, Herak, Janko, Trinajstić, Nenad   +2 more
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Production of pyrimidine dimers in DNA in the dark

Biochemical and Biophysical Research Communications, 1971
Abstract Trimethyl-1,2-dioxetane was decomposed (70°C) in the presence of E.coli DNA. Pyrimidine dimers were detected in the hydrolysate of the reaction mixture. Assuming the existence in cells of reactions which produce electronically excited molecules of sufficient energy these results demonstrate the possibility that pyrimidine photodimers ...
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On the pyrazine and pyrazine–pyrimidine dimers

The Journal of Chemical Physics, 1986
Spectra of the pyrazine-d4, pyrazine-h4–pyrazine-d4, and pyrazine-d4–pyrimidine dimer are obtained and analyzed with the help of Lennard-Jones–hydrogen-bonding (LJ–HB) potential energy calculations. The pyrazine isotopic hetero and homo dimers possess nearly identical spectra with the exception that the perpendicular dimer features are displaced to the
J. Wanna, E. R. Bernstein
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An Enzymatic Assay for Pyrimidine Dimers in DNA

1975
An assay for pyrimidine dimers in DNA employing the T4 endonuclease V is described. The assay can detect approximately 50 dimers per Escherichia coli genome, or the effect of 10 ergs/mm2 ultraviolet irradiation.
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The role of pyrimidine dimers in postreplication repair in Neurospora

Molecular and General Genetics MGG, 1982
Using the Micrococcus luteus dimer specific endonuclease assay of Wilkins (1973), and photoreactivation we have examined the induction and fate of ultraviolet induced pyrimidine dimers in the excision defective strain, uvs-2, of Neurospora crassa. Dimer induction was fluence dependent from 0 to 800 ergs/mm2 UV.
R E, Calza, A L, Schroeder
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PHOTOREPAIR OF NONADJACENT PYRIMIDINE DIMERS BY DNA PHOTOLYASE

Photochemistry and Photobiology, 1995
Abstract— Photolyases reverse the harmful effects of UV light on cells by converting pyrimidine dimers (Pyr[]Pyr) into two pyrimidine monomers by utilizing near‐UV and visible light. Previous work has shown that photolyase repairs T[c,s]T and T[t,s]T in DNA as well as U[]U in RNA, all of which are formed by joining the two adjacent pyrimidines in a ...
S T, Kim, A, Sancar
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Photosensitized splitting of pyrimidine dimers by indole derivatives

Biochemical and Biophysical Research Communications, 1971
Abstract Excitation of tryptophan and 5-hydroxytryptophan at wavelengths longer than 290 and 310 nm, respectively, in the presence of pyrimidine dimers leads to a sensitized splitting of these dimers. The reaction is more efficient in frozen than in fluid aqueous solutions. The fluorescence of tryptophan and 5-hydroxytryptophan is quenched by thymine
C, Helene, M, Charlier
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A rapid and sensitive assay for pyrimidine dimers in DNA

Analytical Biochemistry, 1973
Abstract We have developed a rapid, sensitive assay for pyrimidine dimers. The assay has greatly facilitated the purification and characterization of the photoreactivating enzyme. The procedure depends on (1) the resistance of the nucleotide phosphate bond in dimer-containing regions of DNA to attack by DNase I, venom phosphodiesterase and alkaline ...
B M, Sutherland, M J, Chamberlin
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Mass spectra of some dimeric photoproducts of pyrimidines

Tetrahedron, 1969
Abstract The mass spectra of photo-cycloaddition products of thymines and uracils and a photocoupled product of 5-bromouracil have been measured. Characteristic fragmentation has been documented for dimers joined through a cyclobutane ring, adducts derived from oxetane and azetidine linkages and a coupled product linked through a 5,5′-bond.
C, Fenselau, S Y, Wang
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The formation of pyrimidine dimers in the DNA of fungi and bacteria

Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1973
Abstract The dose-related yields of the three kinds of pyrimidine dimer induced in DNA by ultraviolet light of 254 nm have been measured in three species of bacteria (Escherichia coli, Micrococcus luteus and Bacillus subtilis) and two species of fungi (Saccharomyces cerevisiae and Ustilago maydis).
P, Unrau, R, Wheatcroft, B, Cox, T, Olive   +3 more
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