Results 21 to 30 of about 15,307 (218)
6-[(2-Methylphenyl)sulfanyl]-5-propylpyrimidine-2,4(1H,3H)-dione
Acta Crystallographica Section E, 2014 In the title pyrimidine-2,4-dione derivative, C14H16N2O2S, the dihedral angle between the six-membered rings is 77.81 (10)°. The molecule is twisted about the Cp—S (p = pyrimidine) bond, with a C—S—C—N torsion angle of −59.01 (17)°. An intramolecular C—H.
Nadia G. Haress +4 more
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Crystal structure of N′-hydroxypyrimidine-2-carboximidamide
Acta Crystallographica Section E, 2014 The title compound, C5H6N4O, is approximately planar, with an angle of 11.04 (15)° between the planes of the pyrimidine ring and the non-H atoms of the carboximidamide unit. The molecule adopts an E configuration about the C=N double bond. In the crystal,
Nithianantham Jeeva Jasmine +2 more
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Damage mapping techniques and the light they have shed on canonical and atypical UV photoproducts
Frontiers in Genetics, 2023 Ultraviolet (UV) light is a pervasive threat to the DNA of terrestrial organisms. UV light induces helix-distorting DNA lesions, primarily cyclobutane pyrimidine dimers (CPDs) that form between neighboring pyrimidine bases.
Kaitlynne A. Bohm, John J. Wyrick
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4-Chloro-1H-pyrrolo[2,3-d]pyrimidine
Acta Crystallographica Section E, 2012 The title compound, C6H4ClN3, is essentially planar with the pyrrole and pyrimidine rings inclined to one another by 0.79 (15)°. In the crystal, molecules are connected via pairs of N—H...N hydrogen bonds, forming inversion ...
Su-Lan Dong, Xiaochun Cheng
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Constitutive nitric oxide synthases deficiency impairs cyclobutane pyrimidine dimer repair following solar UV exposure in cells and mice. [PDF]
Photochem PhotobiolProposed model for the dual role of cNOS in DNA damage and repair upon UV radiation. Abstract Solar ultraviolet (sUV) radiation is a major environmental factor that induces DNA damage, promoting skin aging and carcinogenesis. The formation of cyclobutane pyrimidine dimers (CPDs) is one of the most prevalent forms of UV‐induced DNA lesions, playing a ...
Bahamondes Lorca V +8 more
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Acta Crystallographica Section E, 2012 In the title compound, C25H29BrN4O3S2, the benzene rings bridged by the sulfonamide group are tilted relative to each other by 63.9 (1)° and the dihedral angle between the sulfur-bridged pyrimidine and benzene rings is 64.9  ...
Mohan Kumar +5 more
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Acta Crystallographica Section E, 2012 In the title compound, C21H20BrClN4O4S2, the benzene rings bridged by the sulfonamide group are tilted relative to each other by a dihedral angle of 70.2 (1)° and the dihedral angle between the sulfur-bridged pyrimidine and benzene ...
Mohan Kumar +5 more
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(RS)-(2-Bromo-4-fluoroanilino)[2-(4,6-dimethoxypyrimidin-2-yloxy)phenyl]acetonitrile
Acta Crystallographica Section E, 2009 In the title compound, C20H16BrFN4O3, the pyrimidine and 2-bromo-4-fluorophenyl rings are twisted away from the central benzene ring, making dihedral angles of 77.7 (1) and 85.5 (1), respectively.
Yuan-xiang Li
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Crystal structure of 6-chloro-5-isopropylpyrimidine-2,4(1H,3H)-dione
Acta Crystallographica Section E, 2014 In the molecule of the title compound, C7H9ClN2O2, the conformation is determined by intramolecular C—H...O and C—H...Cl hydrogen bonds, which generate S(6) and S(5) ring motifs.
Nadia G. Haress +4 more
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tert-Butyl N-{4-methyl-3-[4-(3-pyridyl)pyrimidin-2-yloxy]phenyl}carbamate
Acta Crystallographica Section E, 2009 In the molecule of the title compound, C21H22N4O3, the pyrimidine ring is oriented at dihedral angles of 0.51 (3) and 50.76 (3)° to the pyridine and benzene rings, respectively. In the crystal structure, intermolecular N&#
Shi-Gui Tang, Jian-Qiang Wang, Cheng Guo
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