Results 21 to 30 of about 11,329 (154)
Ozonolysis of Pyrimidine Nucleosides [PDF]
Bulletin of the Chemical Society of Japan, 1990 Abstract Cytidine, uridine, and thymidine are transformed into the ring-contracted 1-substituted derivatives by ozone. A plausible mechanism is proposed.
Masaki Matsui +3 more
openaire +1 more source
Frontiers in Bioengineering and Biotechnology, 2020 Nucleoside-2′-deoxyribosyl-transferases (NDTs) catalyze a transglycosylation reaction consisting of the exchange of the 2′-deoxyribose moiety between a purine and/or pyrimidine nucleoside and a purine and/or pyrimidine base.
Javier Acosta +5 more
doaj +1 more source
Escherichia Coli Bl21: A Useful Biocatalyst for the Synthesis of Purine Nucleosides
Molecules, 2000 E. coli BL21 cells were able to synthesize several purine nucleosides from pyrimidine ones. Kinetics and yields of this reaction showed a strong dependence on pH, temperature, reagent concentrations and weight of wet cell paste.
A. Iribarren +4 more
doaj +1 more source
Synthesis of some novel hydrazono acyclic nucleoside analogues
Beilstein Journal of Organic Chemistry, 2010 The syntheses of novel hydrazono acyclic nucleosides similar to miconazole scaffolds are described. In this series of acyclic nucleosides, pyrimidine as well as purine and other azole derivatives replaced the imidazole function in miconazole and the ...
Mohammad N. Soltani Rad +2 more
doaj +1 more source
Angewandte Chemie, EarlyView.Fluorine‐18‐labeled CD73 inhibitor [18F]PSB‐19427 enables noninvasive PET mapping of CD73 overexpression in triple‐negative breast (TNBC) and pancreatic cancer. For [18F]PSB‐19427, specific binding in human tumor tissues, favorable biodistribution with prolonged blood retention, robust tumor uptake, and superiority to [18F]FDG in a TNBC model ...
Clemens Dobelmann +23 more
wiley +2 more sources
Palladium-Catalyzed Modification of Unprotected Nucleosides, Nucleotides, and Oligonucleotides
Molecules, 2015 Synthetic modification of nucleoside structures provides access to molecules of interest as pharmaceuticals, biochemical probes, and models to study diseases.
Kevin H. Shaughnessy
doaj +1 more source
Metabolism of pyrimidine L-nucleosides
Nucleic Acids Research, 1976 The intraperitoneal application of L-nucleosides (L-Cyd, L-Urd, L-dThd) to mice results in distribution of these compounds into tissues of the organism and their gradual excretion in the unchanged form. The residual level has been observed with L-ribonucleosides only and contains in addition to the L-nucleoside its 5'-phosphate.
M, Jurovcik, A, Holý
openaire +3 more sources
Nature Communications, 2018 Arabinonucleic acid (ANA) Watson-Crick base-pair with RNA/DNA and can evolve to display enzyme-like function. Here, the authors now identify a prebiotic pathway that yields the complete set of Watson-Crick base-pairing purine and pyrimidine ANA ...
Samuel J. Roberts +7 more
doaj +1 more source
Synthesis of Cyclic and Acyclic Pyrimidine Nucleosides Analogues with Anticipated Antiviral Activity
Acta Chimica Slovenica, 2018 A convenient method for preparation of cyclic and acyclic nucleosides was achieved by alkylation of 6-(2,4-dichlorophenoxymethyl)pyrimidine-2,4-dione (1) with a variety of acyclic and cyclic activated sugar analogues, namely (2-acetoxyethoxy)methyl ...
Mohamed El-Shehry +2 more
doaj +1 more source
Thermus thermophilus Strains Active in Purine Nucleoside Synthesis
Molecules, 2009 Several strains of Thermus thermophilus were tested in order to detect purine nucleoside synthase activity using pyrimidine nucleosides as the sugar-donor and adenine or hypoxanthine as bases.
Marcos Almendros +2 more
doaj +1 more source