Escherichia Coli Bl21: A Useful Biocatalyst for the Synthesis of Purine Nucleosides
Molecules, 2000 E. coli BL21 cells were able to synthesize several purine nucleosides from pyrimidine ones. Kinetics and yields of this reaction showed a strong dependence on pH, temperature, reagent concentrations and weight of wet cell paste.
A. Iribarren +4 more
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Biotransformation of halogenated 2′-deoxyribosides by immobilized lactic acid bacteria [PDF]
, 2012 An efficient and green bioprocess is herein reported to obtain halogenated nucleosides by transglycosylation using immobilized lactic acid bacteria (LAB).
Britos, Claudia Noelia +5 more
core +1 more source
Synthesis of some novel hydrazono acyclic nucleoside analogues
Beilstein Journal of Organic Chemistry, 2010 The syntheses of novel hydrazono acyclic nucleosides similar to miconazole scaffolds are described. In this series of acyclic nucleosides, pyrimidine as well as purine and other azole derivatives replaced the imidazole function in miconazole and the ...
Mohammad N. Soltani Rad +2 more
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Palladium-Catalyzed Modification of Unprotected Nucleosides, Nucleotides, and Oligonucleotides
Molecules, 2015 Synthetic modification of nucleoside structures provides access to molecules of interest as pharmaceuticals, biochemical probes, and models to study diseases.
Kevin H. Shaughnessy
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Metabolism of pyrimidine L-nucleosides
Nucleic Acids Research, 1976 The intraperitoneal application of L-nucleosides (L-Cyd, L-Urd, L-dThd) to mice results in distribution of these compounds into tissues of the organism and their gradual excretion in the unchanged form. The residual level has been observed with L-ribonucleosides only and contains in addition to the L-nucleoside its 5'-phosphate.
M, Jurovcik, A, Holý
openaire +3 more sources
Nature Communications, 2018 Arabinonucleic acid (ANA) Watson-Crick base-pair with RNA/DNA and can evolve to display enzyme-like function. Here, the authors now identify a prebiotic pathway that yields the complete set of Watson-Crick base-pairing purine and pyrimidine ANA ...
Samuel J. Roberts +7 more
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Interaction of Nucleosides and Related Compounds with Nucleic Acids as Indicated by the Change of Helix-Coil Transition Temperature [PDF]
, 1962 A series of compounds has been tested for effectiveness in lowering the melting temperature of poly A and of thymus DNA. The order of increasing activity was found to be: adonitol, methyl riboside (both negligible) < cyclohexanol < phenol, pyrimidine ...
Helmkamp, G. K. +2 more
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Structure of the Ribosomal RNA Decoding Site Containing a Selenium-Modified Responsive Fluorescent Ribonucleoside Probe. [PDF]
, 2017 Comprehensive understanding of the structure-function relationship of RNA both in real time and at atomic level will have a profound impact in advancing our understanding of RNA functions in biology.
Boerneke, Mark A +3 more
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Synthesis of Cyclic and Acyclic Pyrimidine Nucleosides Analogues with Anticipated Antiviral Activity
Acta Chimica Slovenica, 2018 A convenient method for preparation of cyclic and acyclic nucleosides was achieved by alkylation of 6-(2,4-dichlorophenoxymethyl)pyrimidine-2,4-dione (1) with a variety of acyclic and cyclic activated sugar analogues, namely (2-acetoxyethoxy)methyl ...
Mohamed El-Shehry +2 more
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Thermus thermophilus Strains Active in Purine Nucleoside Synthesis
Molecules, 2009 Several strains of Thermus thermophilus were tested in order to detect purine nucleoside synthase activity using pyrimidine nucleosides as the sugar-donor and adenine or hypoxanthine as bases.
Marcos Almendros +2 more
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