Results 131 to 140 of about 68,807 (327)

Investigations into the characterization, degradation, and applications of biodegradable polymers by mass spectrometry

open access: yesMass Spectrometry Reviews, EarlyView., 2023
Abstract Biodegradable polymers have been getting more and more attention because of their contribution to the plastic pollution environmental issues and to move towards a circular economy. Nevertheless, biodegradable materials still exhibit various disadvantages restraining a widespread use in the market.
Paola Rizzarelli   +2 more
wiley   +1 more source

RESEARCHES ON PYRIMIDINES: PYRIMIDINE-NUCLEOSIDES

open access: yesJournal of Biological Chemistry, 1913
Treat B. Johnson, Lewis H. Chernoff
openaire   +2 more sources

A Cytotoxic Indazole‐based Gold(III) Carboxamide Pincer Complex Targeting DNA Through Dual Binding Modes of Groove Binding and Alkylation

open access: yesChemistry – A European Journal, EarlyView.
Toward new gold(III) anticancer agents. Herein, we report on an indazole‐based gold(III) carboxamide pincer complex exhibiting significant cytotoxicity, likely mediated through dual interactions with DNA. Mechanistic investigations suggest that the complex binds to the DNA and forms specific interactions with nucleotide bases.
Rufaro Razuwika   +4 more
wiley   +1 more source

BASIC ESTERS OF SUBSTITUTED PYRIMIDINE-4-CARBOXYLIC ACIDS [PDF]

open access: bronze, 1956
Gordon A. Grant   +2 more
openalex   +1 more source

Iron‐Catalyzed [2+2+2] Cycloadditions for the Construction of Aromatic and Heteroaromatic Rings

open access: yesChemistry – A European Journal, EarlyView.
Iron catalysis has witnessed numerous applications during the last decades. This review is focused on the developments of iron complexes for the construction of aromatic and heteroaromatic rings by [2+2+2] cycloadditions. The importance of the design of the iron coordination sphere along with the use of several co‐catalysts is discussed, as well as the
William Parisot   +4 more
wiley   +1 more source

PYRIMIDINE METABOLISM

open access: hybrid, 1957
E.S. Canellakis
openalex   +1 more source

Design and Evaluation of Bivalent K‐Ras Inhibitors that Target the CAAX Binding Site and the Acidic Surface of Farnesyltransferase and Geranylgeranyltransferase I

open access: yesChemistry – A European Journal, Accepted Article.
Mutant K‐Ras drives cancer through its membrane localization, which requires post‐translational modification by farnesyltransferase (FTase). FTase attaches farnesyl to the K‐Ras C‐terminal CVIM tetrapeptide, enabling membrane binding. However, K‐Ras can also undergo compensatory geranylgeranylation by geranylgeranyltransferase I (GGTase I), making ...
Junko Ohkanda   +8 more
wiley   +1 more source

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