Kinetic mechanisms for the sequence dependence of transcriptional errors. [PDF]
Midha T, Kolomeisky AB, Igoshin OA.
europepmc +1 more source
Regulation of cell proliferation under extreme and moderate hypoxia: the role of pyrimidine (deoxy)nucleotides [PDF]
Øystein Åmellem +2 more
openalex +1 more source
Plant‐type pentatricopeptide repeat proteins capable of C‐to‐U RNA editing perform faithfully when expressed in a new heterologous system, the yeast Saccharomyces cerevisiae. They were tested with constitutive and inducible expression and with a set of different solubility tags. PPR56, PPR65, and PPR78 from P.
Shyam Ramanathan +4 more
wiley +1 more source
Skeletal editing of 4-arylpyrimidines into diverse nitrogen heteroaromatics via four-atom synthons. [PDF]
Li S +15 more
europepmc +1 more source
A novel approach to target skin photodamage: Topical application of salt inducible kinase inhibitors
UV‐induced photodamage leads to increased DNA damage and elevated MMP levels, which degrade collagen and contribute to wrinkle formation. SLT‐001 and SLT‐008, novel cosmetic ingredients that target salt‐inducible kinase, help reverse this effect by enhancing DNA repair, reducing MMP expression and decreasing erythema, thereby mitigating photodamage ...
Inbal Rachmin +7 more
wiley +1 more source
<i>p</i>TSA-catalyzed synthesis of functionalized chromeno[2,3-<i>d</i>]pyrimidine/chromeno[4,3-<i>b</i>]chromene derivatives <i>via</i> one-pot three component reaction: mechanistic insights and variable temperature NMR studies to investigate restricted bond rotation. [PDF]
Singh Tanwer YB +4 more
europepmc +1 more source
The use of nanotechnology in sunscreens has increased, with various filters and organoclays tested for new intercalated formulations. As animal toxicity tests decrease, New Approach Methodologies are favoured. The S4 + OMC‐NC improved cell survival under SSL and showed antimutagenic properties, making it a promising candidate for safe photoprotection ...
Daniel Mabundu Kibwila +6 more
wiley +1 more source
Preparation and characterization of kaolin-[TMS]-NH<sub>2</sub> <sup>+</sup>C(NO<sub>2</sub>)<sub>3</sub> <sup>-</sup> as a novel heterogeneous nano-catalyst and its use in the synthesis of imidazo[1,2-<i>a</i>]pyrimidine and 1,2,4-triazolo[4,3-<i>a</i>]pyrimidines. [PDF]
Dorostkar M +2 more
europepmc +1 more source

