Results 201 to 210 of about 68,807 (327)

An investigation into the transcription factors and regulatory mechanisms of Aspergillus

Food Safety and Health, EarlyView.
Foodborne pathogen Aspergillus, a prevalent etiologic agent among filamentous fungi, are distinguished by a significant repertoire of transcription factors encoded within their genomes. These regulatory proteins are instrumental in orchestrating key biological processes, including cellular growth, secondary metabolite biosynthesis, mycotoxin production,
Yuxin Qin, Huawei Yu, Jun Tian
wiley   +1 more source

Insights into Novel Arylazopyrazolo[1,5-a]pyrimidines as Promising MurA Inhibitors and Antibiofilm Candidates: Design, Synthesis, Antimicrobial Evaluation, and Molecular Docking. [PDF]

ACS Omega
Al Kamaly O, Younes AS, Ibrahim MH, Harras MF, Alsfouk AA, Sabour R.   +5 more
europepmc   +1 more source

Syntheses of Pyrimidine Derivatives. XIV

, 1959
Akira Takamizawa, Kanji Tokuyama
openalex   +2 more sources

Relationship between pyrimidines, purines, and fatty acids in milk of dairy cows fed distinct carbohydrate types: A metabolomic approach. [PDF]

JDS Commun
Giagnoni G, Weisbjerg MR, Errico M, Lapris M, Poulsen NA, Thomsen JPS, Gallo A, Rocchetti G.   +7 more
europepmc   +1 more source

Syntheses of Pyrimidine Derivatives. VII

, 1958
Akira Takamizawa, Kenji Ikawa, Masayuki Narisada   +2 more
openalex   +2 more sources

Emerging Technologies for Timely Point‐of‐Care Diagnostics of Skin Cancer

Global Challenges, EarlyView.
With the global incidence of skin cancer on the rise and a persistent lack of rapid, noninvasive and sensitive point‐of‐care diagnostic platforms, current and emerging technologies are critically reviewed. Among these, the emerging Raman spectroscopy system is identified as a promising complementary to conventional costly and invasive methods, offering
Jarrod L. Thomas, Adrian H. M. Heagerty, Pola Goldberg Oppenheimer   +2 more
wiley   +1 more source

The Impact of the Rs1044457 Polymorphism in the CMPK1 Gene on the Response Rate to Gemcitabine‐Based Chemotherapy in Metastatic NSCLC Patients

Advanced Genetics, EarlyView.
Lung cancer is the leading cause of cancer‐related mortality worldwide. Among its types, non‐small cell lung cancer (NSCLC) accounts for the majority of cases. This study focuses on investigating genetic mutations that may influence the response to gemcitabine, a chemotherapy drug commonly used to treat this condition.
Ghassan Saod Saleh, Fouad Kadhim Gatea, Qasim Sharhan Al‐Mayah, Hayder Lazim   +3 more
wiley   +1 more source

Exploring 4,7-Disubstituted Pyrimido[4,5-d]pyrimidines as Antiviral and Anticancer Agents. [PDF]

Molecules
Georgiou EA, Paraskevas K, Koutra C, Persoons L, Schols D, De Jonghe S, Kostakis IK.   +6 more
europepmc   +1 more source

Integrative cross‐tissue analysis unveils complement‐immunoglobulin augmentation and dysbiosis‐related fatty acid metabolic remodeling during mammalian aging

iMeta, EarlyView.
Our study provides a comprehensive multi‐omics profile of aging, integrating proteomic, metabolomic, and metagenomic analyses across diverse tissues and plasma. We identified the synergistic amplification of the circulating complement system and tissue‐wide immunoglobulin accumulation as key molecular drivers of inflammaging.
Feng Zhang, Rong Li, Yasong Liu, Jinliang Liang, Yihang Gong, Cuicui Xiao, Jianye Cai, Tingting Wang, Qiang You, Jiebin Zhang, Haitian Chen, Jiaqi Xiao, Yingcai Zhang, Yang Yang, Hua Li, Jia Yao, Qi Zhang, Jun Zheng   +17 more
wiley   +1 more source

Isomerization of pirazolopyrimidines to pyrazolopyridines by ring-opening/closing reaction in aqueous NaOH. [PDF]

RSC Adv
Cifuentes C, Bravo N, Restrepo D, Macías M, Portilla J.   +4 more
europepmc   +1 more source