Results 21 to 30 of about 68,807 (327)
Molecules, 2010 The synthesis of the title compounds was achieved using ethyl 2-amino-6-methyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate (1) as starting material.
Hussein El-Kashef +4 more
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Molecules, 2023 An unprecedented oxidative cyclodimerization reaction of 2H-azirine-2-carboxylates to pyrimidine-4,6-dicarboxylates under heating with triethylamine in air is described. In this reaction, one azirine molecule undergoes formal cleavage across the C-C bond
Timofei N. Zakharov +4 more
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Pyrimidine-2-carboxamide [PDF]
Acta Crystallographica Section E Structure Reports Online, 2007 In the crystal strucuture of the title compound, C(5)H(5)N(3)O, which was obtained upon recrystallization of 2-cyano-pyrimidine from aqueous sodium hydroxide, the amide group is twisted with respect to the aromatic ring by 24.9 (1)°. π-π stacking is observed between partially overlapped rings at a face-to-face separation of 3.439 (6) Å.
Jing-Jing Nie, Qian Yang, Bing-Yu Zhang
openaire +3 more sources
Computational Estimation of the Acidities of Pyrimidines and Related Compounds
Molecules, 2022 Pyrimidines are key components in the genetic code of living organisms and the pyrimidine scaffold is also found in many bioactive and medicinal compounds. The acidities of these compounds, as represented by their pKas, are of special interest since they
Rachael A. Holt, Paul G. Seybold
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X-ray photodesorption and proton destruction in protoplanetary disks: pyrimidine [PDF]
Monthly Notices of the Royal Astronomical Society, 08/2013, Volume
433, Issue 4, p.3440-3452, 2013 The organic compounds HCN and C2H2, present in protoplanetary disks, may react to form precursor molecules of the nucleobases, such as the pyrimidine molecule, C4H4N2. Depending on the temperature in a given region of the disk, molecules are in the gas phase or condensed onto grain surfaces.
arxiv +1 more source
Comparative assessment of stability of fungicides triazolopyrimidine, triazole, pyrimidine and morpholine in the soil and prediction of groundwater pollution with them [PDF]
Medičnì Perspektivi, 2016 The purpose of our study was prediction of ground water contamination with fungicides of different chemical classes in soil-climatic conditions of Ukraine and other European countries and hygienic assessment of their harmful effects on human health.
Bіlous S.V. +3 more
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Beilstein Journal of Organic Chemistry, 2011 The Pd/C–CuI–PPh3 catalytic system facilitated C–C bond formation between 4-chlorothieno[2,3-d]pyrimidines and terminal alkynes in methanol with high selectivity without generating any significant side products arising from C–O bond formation between the
Dhilli Rao Gorja +3 more
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Molecules, 2023 The present work describes the design and development of seventeen pyrimidine-clubbed benzimidazole derivatives as potential dihydrofolate reductase (DHFR) inhibitors.
M. Akiful Haque +11 more
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Excited States of Proton-bound DNA/RNA Base Homo-dimers: Pyrimidines [PDF]
Journal of Physical Chemistry B, American Chemical Society, 2014,
119, 6, pp.2219, 2015 We are presenting the electronic photo fragment spectra of the protonated pyrimidine DNA bases homo-dimers. Only the thymine dimer exhibits a well structured vibrational progression, while protonated monomer shows broad vibrational bands. This shows that proton bonding can block some non radiative processes present in the monomer.
arxiv +1 more source
E-Journal of Chemistry, 2009 We here report the virtual screening of several series of pyrimidine derivatives for in silico Thymidylate Synthase (TS) inhibition to arrive at possible potential inhibitors of TS with acceptable pharmacokinetic or ADME (Absorption, Distribution ...
A. G. Nerkar, S. A. Ghone, A. K. Thaker
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