Results 61 to 70 of about 138,736 (279)

Ambient-Light-Promoted Three-Component Annulation: Synthesis of Perfluoroalkylated Pyrimidines.

Organic Letters, 2017
An ambient-light-promoted and metal-free three-component reaction of active methylene compounds, perfluoroalkyl iodides, and guanidines/amidines is reported.
Rui Wang, W. Guan, Zhengbo Han, F. Liang, Takeo Suga, X. Bi, H. Nishide   +6 more
semanticscholar   +1 more source

Proficient synthesis of bioactive annulated pyrimidine derivatives: A review

Journal of Taibah University for Science, 2017
Syntheses of bioactive annulated pyrimidine derivatives are the most significant tasks in N-heterocyclic chemistry because these compounds have proved to be very attractive and useful for the design of new molecular frameworks of potential drugs with ...
Ajmal R. Bhat, Rajendra S. Dongre, Gowhar A. Naikoo, Israr U. Hassan, Tabassum Ara   +4 more
doaj  

Diverse Methods with Stereoselective Induction in the Asymmetric Biginelli Reaction

Molecules
The relevance of the asymmetric Biginelli reaction (ABR) has been increased in this century, due to the pharmacological application of its products. This review focuses predominantly on articles published in the period from 2015 to 2024 on asymmetric ...
Marcos Díaz-Fernández, Manuel Algarra, Saturnino Calvo-Losada, José-Joaquín Quirante, Francisco Sarabia, María-Soledad Pino-González   +5 more
doaj   +1 more source

Amino Derivatives of Diaryl Pyrimidines and Azolopyrimidines as Protective Agents against LPS-Induced Acute Lung Injury

Molecules, 2023
The problem of lung damage originating from excessive inflammation and cytokine release during various types of infections remains relevant and stimulates the search for highly effective and safe drugs.
Alexander Spasov, Irina Ovchinnikova, Olga Fedorova, Yulia Titova, Denis Babkov, Vadim Kosolapov, Alexander Borisov, Elena Sokolova, Vladlen Klochkov, Maria Skripka, Yulia Velikorodnaya, Alexey Smirnov, Gennady Rusinov, Valery Charushin   +13 more
doaj   +1 more source

Implementation of a Quantum Algorithm to Solve Deutsch's Problem on a Nuclear Magnetic Resonance Quantum Computer [PDF]

J.Chem.Phys. 109 (1998) 1648-1653, 1998
We demonstrate the use of an NMR quantum computer based on the pyrimidine base cytosine, and the implementation of a quantum algorithm to solve Deutsch's problem.
arxiv   +1 more source

Microwave assisted synthesis and antimicrobial activity of some novel pyrimidine derivatives [PDF]

Journal of the Serbian Chemical Society, 2007
The synthesis of thiazolo[5,4-d]pyrimidines can be achieved from different 5- thiazolidinones, 2-butyl-1H-imidazole-5-carbaldehyde and thiourea using microwave irradiation within 5 min.
Vaghasia S.J., Shah V.H.
doaj   +3 more sources

Carbazole- and Triphenylamine-Substituted Pyrimidines: Synthesis and Photophysical Properties

Molecules, 2019
A series of pyrimidine derivatives bearing one, two or three triphenylamine/9-ethylcarbazole substituents has been synthesized by Suzuki cross-coupling reaction. All compounds showed absorption bands in the UV region and the emission of violet-blue light
Sylvain Achelle, Julián Rodríguez-López, Massinissa Larbani, Rodrigo Plaza-Pedroche, Françoise Robin-le Guen   +4 more
doaj   +1 more source

Synthesis of New Pyrazole and Pyrimidine Steroidal Derivatives

Molecules, 2003
The synthesis of steroidal heterocycles containing the pyrazole and pyrimidine ring fused to the 16,17-position of the steroid nucleus is reported. Androstenolone acetate (1) reacted with carbon disulfide, iodomethane and sodium hydride to furnish 3β ...
Francisco Coll, Reinaldo Molina, Alina Montero, Isabel Jomarrón, Klaus Peseke, Daniel G. Rivera   +5 more
doaj   +1 more source

Free Radical Scavenging and Cytotoxic Activities of Substituted Pyrimidines [PDF]

arXiv, 2020
A library of substituted pyrimidines was synthesized and evaluated for free radical scavenging, and in vitro cytotoxic activity in 3T3 cells. All compounds showed good free radical scavenging activity with IC50 values in the range of 42.9 + 0.31 to 438.3 3.3 {\mu}M as compared to the standard butylated hydroxytoluene having IC50 value of 128.83 2.
arxiv  

The LANCA three-component reaction to highly substituted β-ketoenamides – versatile intermediates for the synthesis of functionalized pyridine, pyrimidine, oxazole and quinoxaline derivatives

Beilstein Journal of Organic Chemistry, 2019
The LANCA three-component reaction of lithiated alkoxyallenes LA, nitriles N and carboxylic acids CA leads to β-ketoenamides KE in good to excellent yields.
Tilman Lechel, Roopender Kumar, Mrinal K. Bera, Reinhold Zimmer, Hans-Ulrich Reissig   +4 more
doaj   +1 more source