Results 61 to 70 of about 68,807 (327)

Implementation of a Quantum Algorithm to Solve Deutsch's Problem on a Nuclear Magnetic Resonance Quantum Computer [PDF]

J.Chem.Phys. 109 (1998) 1648-1653, 1998
We demonstrate the use of an NMR quantum computer based on the pyrimidine base cytosine, and the implementation of a quantum algorithm to solve Deutsch's problem.
arxiv   +1 more source

Adjusting Cell‐Surface Interactions Through a Covalent Immobilization of Biomolecules

Advanced Materials Interfaces, EarlyView.
This review presents an overview of current and emerging immobilization techniques coupled with an in‐depth investigation of the underlying mechanisms governing the activity and stability of covalently immobilized biomolecules. The aim of this study is to serve as a guide for the development of long‐lasting biomedical coatings with versatile biological
Sara Shakibania, Manus J. P. Biggs, Katarzyna Krukiewicz   +2 more
wiley   +1 more source

Oligonucleotides Featuring a Covalently Mercurated 6‐Phenylcarbazole Residue as High‐Affinity Hybridization Probes for Thiopyrimidine‐Containing Sequences

Chemistry – A European Journal, Volume 28, Issue 69, December 9, 2022., 2022
Getting back to (nucleo)base: Oligonucleotides incorporating a central 1‐ or 8‐mercuri‐6‐phenyl‐1H‐carbazole residue show great promise as high‐affinity hybridization probes, discriminating between all canonical nucleobases as well as 2‐ and 4‐thiothymines by melting temperature margins of at least 5 °C.
Tharun K. Kotammagari, Petri Tähtinen, Tuomas Lönnberg   +2 more
wiley   +1 more source

Amino Derivatives of Diaryl Pyrimidines and Azolopyrimidines as Protective Agents against LPS-Induced Acute Lung Injury

Molecules, 2023
The problem of lung damage originating from excessive inflammation and cytokine release during various types of infections remains relevant and stimulates the search for highly effective and safe drugs.
Alexander Spasov, Irina Ovchinnikova, Olga Fedorova, Yulia Titova, Denis Babkov, Vadim Kosolapov, Alexander Borisov, Elena Sokolova, Vladlen Klochkov, Maria Skripka, Yulia Velikorodnaya, Alexey Smirnov, Gennady Rusinov, Valery Charushin   +13 more
doaj   +1 more source

Purinylidene‐Based Iridium(III) Phosphors for Efficient Purple Phosphorescence and Organic Light‐Emitting Devices

Advanced Photonics Research, EarlyView.
A family of purinylidene based Ir(III) emitters, namely, f‐ct2a–d, are synthesized and utilized as both dopants and sensitizers in the construction of efficient purple to deep‐blue organic light‐emitting diode devices. It is very challenging to achieve highly efficient and low roll‐off purple to deep‐blue organic light‐emitting diodes (OLEDs) due to ...
Jie Yan, Yi Pan, Zhi‐Hao Qu, Zihan Xu, Kwok‐Chung Law, Dong‐Ying Zhou, Liang‐Sheng Liao, Yun Chi, Kai‐Chung Lau   +8 more
wiley   +1 more source

Free Radical Scavenging and Cytotoxic Activities of Substituted Pyrimidines [PDF]

arXiv, 2020
A library of substituted pyrimidines was synthesized and evaluated for free radical scavenging, and in vitro cytotoxic activity in 3T3 cells. All compounds showed good free radical scavenging activity with IC50 values in the range of 42.9 + 0.31 to 438.3 3.3 {\mu}M as compared to the standard butylated hydroxytoluene having IC50 value of 128.83 2.
arxiv  

Continuous Flow Technology Enabling Photochemistry

Advanced Synthesis &Catalysis, Accepted Article.
The merger of continuous flow technology and modern photochemistry has enabled countless applications showcasing new opportunities for chemical synthesis demonstrating improvements in selectivity, safety, sustainability and scalability. This focused review aims to highlight a selection of recently published case studies from academic and industrial ...
Ruairi Crawford, Marcus Baumann
wiley   +1 more source

A Multi‐Objective Molecular Generation Method Based on Pareto Algorithm and Monte Carlo Tree Search

Advanced Science, EarlyView.
Pareto Monte Carlo Tree Search Molecular Generation (PMMG), a molecular generation approach leveraging Monte Carlo Tree Search (MCTS) and Pareto algorithm, efficiently explores the Pareto front in high‐dimensional objective spaces for multi‐objective drug design.
Yifei Liu, Yiheng Zhu, Jike Wang, Renling Hu, Chao Shen, Wanglin Qu, Gaoang Wang, Qun Su, Yuchen Zhu, Yu Kang, Peichen Pan, Chang‐Yu Hsieh, Tingjun Hou   +12 more
wiley   +1 more source

Synthesis and polymerization of 1-(2-diallylaminoethyl)pyrimidines

Designed Monomers and Polymers, 2018
We report the preparation and characterization of three pyrimidine-based monomers, specifically: 1-(2-diallylaminoethyl)uracil, 1-(2-diallylaminoethyl)thymine and 1-(2-diallylaminoethyl)cytosine.
Jomana Elaridi, Alaa Ezzeddine, Lara Abramian, Ali Koubeissi, Nikolay Vladimirov, Kamal H. Bouhadir   +5 more
doaj   +1 more source

Purine-pyrimidine symmetry, determinative degree and DNA [PDF]

arXiv, 2000
Various symmetries connected with purine-pyrimidine content of DNA sequences are studied in terms of the intruduced determinative degree, a new characteristics of nucleotide which is connected with codon usage. A numerological explanation of CG pressure is proposed. A classification of DNA sequences is given.
arxiv