Results 151 to 160 of about 3,593 (197)

A plain language summary describing changes in pain associated with uterine fibroids among women receiving relugolix combination therapy. [PDF]

open access: yesPain Manag
Stewart EA   +7 more
europepmc   +1 more source

Nanoparticle-Catalysed Microwave-Driven MCRs for Sustainable Heterocycle Synthesis. [PDF]

open access: yesMolecules
Kasi V   +5 more
europepmc   +1 more source

A single-center retrospective study of dabrafenib plus trametinib combination therapy in patients with BRAF V600E-positive thyroid cancer. [PDF]

open access: yesInt J Clin Oncol
Ando T   +9 more
europepmc   +1 more source

Synthesis and anticancer potential of glycosides. [PDF]

open access: yesRSC Adv
Ali S   +5 more
europepmc   +1 more source

New Pyrimidinone and Fused Pyrimidinone Derivatives as Potential Anticancer Chemotherapeutics

Archiv der Pharmazie, 2012
AbstractA series of novel substituted pyrimidinones and fused pyrimidinones (compounds 3–18) were synthesized starting with oxiranylmethanone 2. The in vitro cytotoxicity against a human breast adenocarcinoma (MCF‐7) cell line was investigated and most of the tested compounds showed potent cytotoxic activity against the MCF‐7 cell line comparable to ...
Aymn E, Rashad   +7 more
openaire   +2 more sources

Ethynyltriisopropoxytitanium reactions with pyrimidinones

Journal of Organometallic Chemistry, 1988
Abstract Ethynyltriisopropoxytitanium has been generated in situ from ethynyllithium and chlorotriisopropoxytitanium at −80°C. It forms 1 1 adducts with pyrimidin-2(1 H )-ones with exclusive carbon-carbon bond formation at C(6). The products after quenching ethynylmagnesium bromide with chlorotriisopropoxytitanium at −10°C are 1 1 the ...
Frode Rise, David Grace, Kjell Undheim
openaire   +1 more source

Synthesis of fluorinated pyrimidinones

Journal of Fluorine Chemistry, 2013
Abstract A method for the construction of fluorinated pyrimidinones based on the reaction of cyanodifluoromethyl-substituted amines with isocyanates is described. The use of ortho-iodophenylisocyanate in this reaction followed by copper catalyzed intramolecular amination affords fluorinated fused heterocycles – 4-fluoropyrimido[1,6-a]benzimidazol-1 ...
Mikhail D. Kosobokov   +4 more
openaire   +1 more source

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