Results 51 to 60 of about 2,914 (164)

Optimization of Anti-kinking Designs for Vascular Grafts Based on Supramolecular Materials

Frontiers in Materials, 2020
Synthetic vascular grafts to be applied as access grafts for hemodialysis often require anti-kinking properties. Previously, electrospun microporous vascular implants based on synthetic supramolecular materials have been shown to perform adequately as ...
Dan Jing Wu, Dan Jing Wu, Dan Jing Wu, Kim van Dongen, Kim van Dongen, Kim van Dongen, Wojciech Szymczyk, Wojciech Szymczyk, Paul J. Besseling, Ruth M. Cardinaels, Giulia Marchioli, Giulia Marchioli, Giulia Marchioli, Marcel H. P. van Genderen, Marcel H. P. van Genderen, Carlijn V. C. Bouten, Carlijn V. C. Bouten, Anthal I. P. M. Smits, Anthal I. P. M. Smits, Patricia Y. W. Dankers, Patricia Y. W. Dankers, Patricia Y. W. Dankers   +21 more
doaj   +1 more source

Time-Efficient Synthesis of Pyrido[2,3-d]pyrimidinones via α-Oxoketenes

, 2016
International audienceα-Oxoketene reactive intermediates generated in situ by microwave-assisted Wolff rearrangement of 2-diazo-1,3- dicarbonyl compounds have been found to react with 6-amino-pyrimidine derivatives as 1,3-C,N-bis-nucleophiles to yield ...
Coquerel, Yoann, Jairo Quiroga, Castillo, Juan Carlos, Juan‐Carlos Castillo, Castillo, Juan-Carlos, Jean Rodriguez, Rodriguez, Jean, Yoann Coquerel, Quiroga, Jairo   +8 more
core   +1 more source

Evaluation of Neurotropic Activity and Molecular Docking Study of New Derivatives of pyrano[4″,3″:4′,5′]pyrido[3′,2′:4,5]thieno[3,2-d]pyrimidines on the Basis of pyrano[3,4-c]pyridines

Molecules, 2022
Background: Heterocyclic compounds and their fused analogs, which contain pharmacophore fragments such as pyridine, thiophene and pyrimidine rings, are of great interest due to their broad spectrum of biological activity.
Shushanik Sh. Dashyan, Eugene V. Babaev, Ervand G. Paronikyan, Armen G. Ayvazyan, Ruzanna G. Paronikyan, Lernik S. Hunanyan   +5 more
doaj   +1 more source

Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future

Medicinal Research Reviews, EarlyView.
ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley   +1 more source

Mechanistic Investigations into the photochemistry of 4-allyl-tetrazolones in solution: a new approach to the synthesis of 3,4-dihydro-pyrimidinones

, 2014
Photolysis (ì ) 254 nm) of 4-allyl-tetrazolones 2a-c was carried out in methanol, 1-propanol, 1-hexanol, acetonitrile, and cyclohexane. The sole primary photochemical process identified was molecular nitrogen elimination, with formation of pyrimidinones ...
Khmelinskii, Igor, Cristiano, Maria Lurdes Santos, Frija, L.   +2 more
core   +1 more source

Conjugated Polymers Engineered for Flexible/Stretchable Electronics

Journal of Polymer Science, EarlyView.
This review highlights glass transition temperature (Tg) as the central parameter linking molecular structure to device performance in conjugated polymers. By tuning backbone rigidity, side‐chain architecture, and dynamic bonding, Tg governs the balance between π–π stacking–enabled charge transport and mechanical compliance.
Yunchong Yang, Josh Bass, Weijia Yan, Ashwath Anand, Chunka Zhou, Jingjing Qiu   +5 more
wiley   +1 more source

Tuning the Annulation Reactivity of Vinyl Azides and Carbazates: A Divergent Synthesis of Aza-pyrimidinones and Imidazoles

, 2015
A divergent cascade annulation has been developed using readily available vinyl azides and carbazates with a wide range of substituents. Vinyl azides were successfully applied as bifunctional partners to prepare aza-pyrimidinones via 6-ring closure with ...
Wenteng Chen (1528783), Jiaan Shao (1528792), Ke Shu (1528786), Jing Luo (146659), Pai Tang (1528795), Xingyu Liu (1528789), Yongping Yu (1520146)   +6 more
core   +2 more sources

Synthesis, anticancer activity and molecular docking of new quinolines, quinazolines and 1,2,4-triazoles with pyrido[2,3-d] pyrimidines

Heliyon
Recently, heterocyclic compounds such as pyrido [2,3-d] pyrimidinones, 1,2,4-triazolopyrimidines, pyrimidoquinazolines, and quinoline derivatives have gained attention from researchers due to their pharmacological and biological activities. To synthesize
Ameen Ali Abu-Hashem, Othman Hakami, Nasser Amri   +2 more
doaj   +1 more source

Synthesis of Some Thienopyrimidine Derivatives

Molecules, 2006
Thioxothienopyrimidinones, alkylthio- and arylalkylthiothienopyrimidinones, thienopyrimidinones, thienopyrimidines a thienopyrimidinedione and a thienotriazolo- pyrimidinone were prepared from 2-amino-3-carboethoxy-4,5-disubstituted thiophenes and 2 ...
Hassan M. Al-Hazimi, Hanan A. S. Al-Blowy, Fatma E. M. El-Baih   +2 more
doaj   +1 more source

Binder Design in Extrusion‐Based 3D Printing of Electrodes: Enhancing Printability and Electrochemical Performance in Energy Storage Devices

Small, EarlyView.
Binder design plays a pivotal role in extrusion‐based 3D printing of energy storage electrodes by simultaneously governing ink printability and electrochemical performance. This review examines how diverse binder materials and design strategies are employed to enable printability while addressing key electrochemical challenges in energy storage devices,
Akesh Manimendra Badalge, Timothy J. Biddle, Huynh Tam Minh Nguyen, Eric Campbell, Munkhbayar Batmunkh, Tak Kim, Stefanie Feih, Yu Lin Zhong   +7 more
wiley   +1 more source