Results 51 to 60 of about 5,835 (244)

Synthesis of Isoxazolo[4,5‐D]Pyrimidinones, and their Isomerization into Oxazolo[4,5‐D]Pyrimidinones on Flash Vacuum Pyrolysis

Bulletin des Sociétés Chimiques Belges, 1994
AbstractA series of new 3‐phenylisoxazolo[4,5‐d]pyrimidinones 5a‐d were prepared from 5‐aminoisoxazole‐4‐carboxylic acid esters. Upon flash‐vacuum pyrolysis, these heterocycles are isomerized into hitherto unreported 2‐phényloxazolo[4,5‐d] ‐pyrimidinones 8a‐d.
Laurent, Sophie, Flammang, Robert, Barbieux-Flammang, Monique, Van Haverbeke, Yves, Wentrup, Curt   +4 more
openaire   +5 more sources

Mechanistic Investigations into the Photochemistry of 4-Allyl-tetrazolones in Solution:  A New Approach to the Synthesis of 3,4-Dihydro-pyrimidinones [PDF]

, 2016
Photolysis (λ = 254 nm) of 4-allyl-tetrazolones 2a−c was carried out in methanol, 1-propanol, 1-hexanol, acetonitrile, and cyclohexane. The sole primary photochemical process identified was molecular nitrogen elimination, with formation of pyrimidinones ...
M. Lurdes S. Cristiano (2248654), Igor V. Khmelinskii (2642482), Luís M. T. Frija (2495575)   +2 more
core   +1 more source

Self-assembled pentamers and hexamers linked through quadruple-hydrogen-bonded 2-ureido-4 [1H]-pyrimidinones [PDF]

, 2005
The preorganization of bifunctional 2-ureido-4-pyrimidinones mediated by either 1,3-substituted adamantane or meta-substituted phenylene ring linkers leads to the preferred formation of stable pentameric (1)5 and hexameric (2)6 assemblies, respectively ...
Mendoza, J de, Segura, M, Prados, P, Meijer, E.W., Henk M. Keizer, Sijbesma, RP Rint, Keizer, H.M., Sijbesma, R.P., Meijer, EW Bert, Gonzalez, J.J., Segura, M., Margarita Segura, E. W. Meijer, Keizer, HM Henk, Rint P. Sijbesma, Gonzalez, JJ, Pilar Prados, Prados, P., Juan J. González, Javier de Mendoza, Mendoza, de, J.   +20 more
core   +1 more source

Synthesis and biological activity of some new fused thieno[2,3-b] pyridine derivatives; pyridothienopyrimidinones and pyridothienotriazinones [PDF]

Assiut University Journal of Multidisciplinary Scientific Research, 2016
3-Amino-4-aryl-5-ethoxycarbonyl-6-methylthieno[2,3-b]pyrindine-2-carboxamides 3a,b wereprepared and reacted with triethyl orthoformate to give pyridothienopyrimidinone derivatives4a,b.
doaj   +1 more source

Straightforward synthesis, characterization, and cytotoxicity evaluation of hybrids of natural alkaloid evodiamine/rutaecarpine and thieno[2,3-d]pyrimidinones [PDF]

, 2018
Dozens of hybrids of natural alkaloid evodiamine/rutaecarpine and thieno[2,3-d]pyrimidinones were synthesized in a straightforward method by condensation of substituted 2H-thieno[2,3-d][1, 3]oxazine-2,4(1H)-diones or N-methyl-2H-thieno[2,3-d][1, 3 ...
Jian-Guo Cao (6159491), Guo-Zheng Huang (6159500), Si-Si Wang (2035588), Fei-Ze Liu (6159494), Haji Akber Aisa (7312430), Li-Fei Nie (6159488), Hainimu Xiamuxi (6159497)   +6 more
core   +1 more source

A Synthetic Approach to Pyrazolopyranopyrimidinones and Pyrazolopyranooxazinones as Antimicrobial Agents

Journal of Chemistry, 2016
The hitherto unknown 6-amino-4-(2-chloro-5-nitrophenyl)-3-methyl-1,4-dihydropyrano[2,3-c] pyrazole-5-carbonitrile 1a was synthesized. Both 1a and its 2,4 dichlorophenyl derivative 1b were utilized as building blocks for the preparation of novel class of ...
A. K. Elziaty, G. Bassioni, A. M. A. Hassan, H. A. Derbala, M. S. Abdel-Aziz   +4 more
doaj   +1 more source

Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future

Medicinal Research Reviews, EarlyView.
ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley   +1 more source

Straightforward synthesis, characterization, and cytotoxicity evaluation of hybrids of natural alkaloid evodiamine/rutaecarpine and thieno[2,3-d]pyrimidinones

Journal of Asian natural products research, 2018
Dozens of hybrids of natural alkaloid evodiamine/rutaecarpine and thieno[2,3-d]pyrimidinones were synthesized in a straightforward method by condensation of substituted 2H-thieno[2,3-d][1, 3]oxazine-2,4(1H)-diones or N-methyl-2H-thieno[2,3-d][1, 3 ...
L. Nie, Siquan Wang, Jianguo Cao, Feize Liu, H. Xiamuxi, H. Aisa, Guozheng Huang   +6 more
semanticscholar   +1 more source

Conjugated Polymers Engineered for Flexible/Stretchable Electronics

Journal of Polymer Science, EarlyView.
This review highlights glass transition temperature (Tg) as the central parameter linking molecular structure to device performance in conjugated polymers. By tuning backbone rigidity, side‐chain architecture, and dynamic bonding, Tg governs the balance between π–π stacking–enabled charge transport and mechanical compliance.
Yunchong Yang, Josh Bass, Weijia Yan, Ashwath Anand, Chunka Zhou, Jingjing Qiu   +5 more
wiley   +1 more source

The role of phosphotungstic acid in enhancing the catalytic performance of UiO-66 (Zr) and its applications as an efficient solid acid catalyst for coumarins and dihydropyrimidinones synthesis

Catalysis Communications, 2022
In recent study, we report a facile and easy technique for the synthesis phosphotungstic acid (PTA) with different weight contents (10, 25, 50 and 75 wt%) loaded on UiO-66 (Zr) as efficient and reusable catalysts for the preparation of coumarin and ...
Fares T. Alshorifi, Dina E. Tobbala, Salah M. El-Bahy, Mohamed A. Nassan, Reda S. Salama   +4 more
doaj   +1 more source