Results 51 to 60 of about 3,637 (213)
The synthesis of 2-pyrimidinone nucleosides and their incorporation into oligodeoxynucleotides
The synthesis of 1-(beta-D-2'-deoxyribosyl)-2-pyrimidinone (dK) and its 5-methyl derivative (d5) from 2'-deoxycytidine or 2'-deoxythymidine, respectively, via silver oxide oxidation of 4-hydrazinopyrimidines is described. The necessary hydrazine substituted pyrimidine nucleosides have been prepared by transamination of a protected cytidine derivative ...
B, Gildea, L W, McLaughlin
openaire +3 more sources
The self‐assembly of carbon dots, which enables precise control over their macroscopic architectures and collective properties, profoundly enhances their functionality. This review systematically summarizes the field through four key aspects—morphology control, luminescence modulation, assembly mechanisms, and advanced applications—and thereby offers a
Kai Chen +5 more
wiley +1 more source
Gap Analysis of Metabolic Conversions of Off‐Flavors and Antinutrients in Plant‐Based Substrates
ABSTRACT To drastically reduce the carbon footprint of the food production chain, a major shift towards alternatives to conventional meat and dairy products is required. The use of plant‐based proteins is a promising route, but it also comes with challenges: Plant‐based proteins often contain antinutritional factors and off‐flavors, which can ...
Robin I. Kuijpers +16 more
wiley +1 more source
Synthesis of Some Thienopyrimidine Derivatives
Thioxothienopyrimidinones, alkylthio- and arylalkylthiothienopyrimidinones, thienopyrimidinones, thienopyrimidines a thienopyrimidinedione and a thienotriazolo- pyrimidinone were prepared from 2-amino-3-carboethoxy-4,5-disubstituted thiophenes and 2 ...
Hassan M. Al-Hazimi +2 more
doaj +1 more source
Heterogeneous catalysis has historically been developed in the gas phase, however, we have found it pertinent to highlight solvent effects that must be accounted for in liquid environments. Condensed phase catalysis, like that in biomass, petroleum and the conversion of CO2, stands to benefit from the typically overlooked discussion regarding the ...
Jim B. Floyd +3 more
wiley +1 more source
Recently, heterocyclic compounds such as pyrido [2,3-d] pyrimidinones, 1,2,4-triazolopyrimidines, pyrimidoquinazolines, and quinoline derivatives have gained attention from researchers due to their pharmacological and biological activities. To synthesize
Ameen Ali Abu-Hashem +2 more
doaj +1 more source
A novel VIVO–pyrimidinone complex: synthesis, solution speciation and human serum protein binding [PDF]
The pyrimidinones mhcpe, 2-methyl-3H-5-hydroxy-6-carboxy-4-pyrimidinone ethyl ester (mhcpe, 1), 2,3- dimethyl-5-benzyloxy-6-carboxy-4-pyrimidinone ethyl ester (dbcpe, 2) and N-methyl-2,3-dimethyl-5- hydroxy-6-carboxyamido-4-pyrimidinone (N-MeHOPY, 3 ...
Avecilla, Fernando +11 more
core +1 more source
Hydrogels for Bone Repair: Construction Strategies and Applications
This review establishes an integrated framework for bone repair hydrogels, covering construction strategies from material selection to functional modification, mechanical and biological characterization, and diverse applications including defect repair, fracture healing, and smart responsive systems.
Miaomiao Wang +7 more
wiley +1 more source
This review highlights ionic liquid‐based self‐healing polymer electrolytes as a promising route toward safer, resilient solid‐state batteries. By combining nonvolatile plasticization, dynamic supramolecular interactions, and tailored polymer architectures, these materials can simultaneously improve ionic conductivity, mechanical robustness, and ...
Zhijun Wu +6 more
wiley +1 more source
Pyrimidinone: versatile Trojan horse in DNA photodamage?
Abstract (6-4) Photolesions between adjacent pyrimidine DNA bases are prone to secondary photochemistry. It has been shown that singlet excited (6-4) moieties form Dewar valence isomers as well as triplet excitations. We here report on the triplet state of a minimal model for the (6-4) photolesion, 1-methyl-2(1H)-pyrimidinone.
Mathias, Micheel +3 more
openaire +3 more sources

