Results 71 to 80 of about 2,914 (164)

Mechanically Robust and Wear‐Resistant 3D‐Printable Polyurethane Elastomers Through UPy‐Based Supramolecular Reinforcement

open access: yesAggregate, Volume 7, Issue 9, September 2026.
This work develops a high‐performance photopolymerizable polyurethane elastomer by incorporating quadruple H‐bonding UPy moieties into its backbone, achieving exceptional mechanical robustness, superior puncture and abrasion resistance, and an extremely low wear rate. The dynamic supramolecular network forms a microphase‐separated structure through the
Xingxing Yang   +10 more
wiley   +1 more source

Synthesis of thiophene and N-substituted thieno[3,2-d] pyrimidine derivatives as potent antitumor and antibacterial agents

open access: yesActa Pharmaceutica, 2017
A novel series of carbamothioylamino-benzene-sulfonamide-thiophene-carboxylates 4a-c and thieno[3,2-d]pyrimidin-2-yl-amino-benzene-sulfonamides 5a-c were synthesized in a series of synthetic steps and were used as key intermediates for the synthesis of ...
Hafez Hend N.   +2 more
doaj   +1 more source

Regioselectivity of alkylation reaction of 2-oxo-(thio)-3-phenyl-thieno[2,3-d]pyrimidinones

open access: yes, 2020
The elaboration of easy and affordable highly selective methods for the synthesis of thieno[2,3-d]pyrimidine derivatives, which operate on none toxic reagents and energy-saving techniques, is an urgent task of organic chemistry.
Сливка, Михайло Васильович   +5 more
core  

Green Synthesis of Pyrazol‑chromeno[2,3‑d]pyrimidinones Using SBA-Pr-SO3H as an Efficient Nanocatalyst [PDF]

open access: yesIranian Journal of Chemistry & Chemical Engineering, 2017
Hexagonal mesoporous silica (SBA-15) was prepared and then functionalized by(3-mercaptopropyl)trimethoxysilane. The obtained 3-mercaptopropyl functionalized SBA-15 (SBA-Pr-SH) was then oxidized using H2O2 in methanol under an acidic condition to give ...
Ghodsi Mohammadi Ziarani   +4 more
doaj  

Identification of Novel Class of Triazolo-Thiadiazoles as Potent Inhibitors of Human Heparanase and their Anticancer Activity

open access: yesBMC Cancer, 2017
Background Expression and activity of heparanase, an endoglycosidase that cleaves heparan sulfate (HS) side chains of proteoglycans, is associated with progression and poor prognosis of many cancers which makes it an attractive drug target in cancer ...
C. P. Baburajeev   +9 more
doaj   +1 more source

Chemoselective reactions of N1-methyl-2-hydroxy-3-methylamino-3-phenylpropanamide with electrophiles. Synthesis of chiral hexahydro-4-pyrimidinones and oxazolidines

open access: yes, 2002
The reactivity of (2S,3S)-N1-methyl-2-hydroxy-3-methylamino-3-phenylpropanamide 1, containing three nucleophilic centres has been studied against dihaloalkanes and aldehydes.
Hajji C.   +5 more
core   +1 more source

NITROIMIDAZOLES XI1 [I]: SYNTHESES OF TRISUBSTITUTED PYRAZOLES AND SUBSTITUTED (1 -METHYL-5-NITRO-2- IMIDAZOLYL) PYRIMIDINONES [PDF]

open access: yesJournal of Sciences, Islamic Republic of Iran, 1995
The reaction of P-diketones 1 with phenyl hydrazine afforded 5-aryl-3-(1- methyl-5-nitro-2-imidazoly1)-1-phenylpyrazole (2) and 3-aryl-5-(1-methyl-5- nitro-2-imidazoly1) -1-phenylpyrazole (3).
doaj  

Application of cyclic-1,3-diketones in domino and multicomponent reactions: facile route to highly functionalized chromeno[2,3-d]pyrimidinones and diazabenzo[b]fluorenones under solvent-free conditions

open access: yes, 2010
A facile and efficient protocol for the synthesis of chromeno[2,3-d]pyrimidinones and diazabenzo[b]fluorenones has been developed by one-pot three-component cyclocondensation of aldehydes, cyclic-1,3-diketones and 1,3-dimethylbarbituric acid in the ...
Rajiv K. Verma   +7 more
core   +1 more source

An unexpected and efficient direct nucleophilic C-4 hydroxy substitution on 2-methoxy- and 2-mrthylthio-4(3H)-pyrimidinones bearing a diethylamino moiety on the C-6 side chain

open access: yes, 1997
The unexpected and efficient direct nucleophilic C-4 hydroxy (oxo) substitution by sodium alkoxides on 2-methoxy- and 2-methylthio-4(3H)- pyrimidinones bearing a diethylamino moiety on the c-6 side chain is reported.
BOTTA M   +9 more
core   +2 more sources

One-Pot Eco-Safe Saccharin-Catalyzed Procedure for Expedient and Convenient Synthesis of Dihydropyrano[2,3-c]pyrazole, Tetrahydrobenzo[b]pyran and Pyrano[2,3-d]pyrimidinone Scaffolds as a Green and Versatile Catalyst

open access: yesIndonesian Journal of Chemistry, 2018
A green and facile saccharin-catalyzed procedure is developed for the one-pot convenient synthesis of dihydropyrano[2,3-c]pyrazole, tetrahydrobenzo[b]pyran and pyrano[2,3-d]pyrimidinone scaffolds via multi-component tandem Knoevenagel cyclocondensation ...
Farzaneh Mohamadpour   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy