Results 21 to 30 of about 9,191 (227)

A Concise Synthesis of Rhodanthpyrone A and B, Natural 4-(Hydroxyphenyl)-substituted α-Pyrones

Natural Product Communications, 2017
A concise synthesis of rhodanthpyrone A and B was accomplished via a Suzuki coupling reaction. To find the conditions appropriate to install hydroxyphenyl moieties to the α-pyrone skeleton, a model study was conducted using commercially available boronic
Young Taek Han
doaj   +1 more source

Assessment on facile Diels–Alder approach of α-pyrone and terpenoquinone for the expedient synthesis of various natural scaffolds

Natural Products and Bioprospecting, 2022
The development of highly facile synthetic procedures for the expedient synthesis of complex natural molecules is always in demand. As this aspect, the Diels–Alder reaction (DAR) has a versatile approach to the synthesis of complex natural compounds and ...
Aluru Rammohan, Albert F. Khasanov, Dmitry S. Kopchuk, Duvvuru Gunasekar, Grigory V. Zyryanov, Oleg N. Chupakhin   +5 more
doaj   +1 more source

Synthesis of an Antileukemic Pyrone from

Natural Product Communications, 2017
Antileukemic pyrone 1 was synthesized by way of a five-step procedure from 4 -Hydroxy-5-methoxycarbonyl-6-methyl-2-pyrone (8). This is the first synthesis of 4-methoxy-6-methyl-5-(3-oxobutyl)-2H-pyran-2-one (1).
Yang Qu, George A. Kraus
doaj   +1 more source

Divergent Asymmetric Total Synthesis of All Four Pestalotin Diastereomers from (R)-Glycidol

Molecules, 2020
All four chiral pestalotin diastereomers were synthesized in a straightforward and divergent manner from common (R)-glycidol. Catalytic asymmetric Mukaiyama aldol reactions of readily-available bis(TMSO)diene (Chan’s diene) with (S)-2 ...
Mizuki Moriyama, Kohei Nakata, Tetsuya Fujiwara, Yoo Tanabe   +3 more
doaj   +1 more source

Tricarbonyl(η6-4′,7-dimethoxyisoflavone)chromium(0)

Acta Crystallographica Section E, 2009
The metal atom of the Cr(CO)3 unit of the title compound, [Cr(C17H14O4)(CO)3], is coordinated to the methoxyphenyl ring of the isoflavone ligand; the Cr(CO)3 unit exhibits a three-legged piano-stool conformation.
Johannes H. van Tonder, Barend C. B. Bezuidenhoudt, J. Marthinus Janse van Rensburg   +2 more
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Convergent Total Synthesis of 16β‐Hydroxylpseudobufarenogin

Angewandte Chemie, Volume 138, Issue 23, 1 June 2026.
We present a novel convergent strategy that integrates Pd/Ag‐promoted Suzuki–Miyaura coupling with Ir‐catalyzed radical‐relay cyclization, enabling the first total synthesis of 16β‐hydroxylpseudobufarenogin. This approach is broadly applicable to the total synthesis of various oxygenated bufadienolides by simply modifying the fragment structures ...
Wataru Shigematsu, Yo Matsumoto, Koichi Hagiwara, Masayuki Inoue   +3 more
wiley   +2 more sources

Isothiourea-mediated one-pot synthesis of trifluoromethyl substituted 2-pyrones

, 2014
The authors thank the Royal Society for a University Research Fellowship (ADS) and the EPSRC (EP/J018139/1, DSBD) for funding.A one-pot isothiourea-mediated Michael addition/lactonization/thiol elimination cascade sequence for the formation of 4,6 ...
Smith, Andrew D., Pei-Pei Yeh (1849192), Daniels, David S. B., David S. B. Daniels (1829398), Alexandra M. Z. Slawin (1489162), Cordes, David B., Slawin, Alexandra M. Z., David B. Cordes (809266), Yeh, Pei-Pei, Andrew D. Smith (494170)   +9 more
core   +1 more source

Di-µ-(1-(3-(1H-imidazol-1-yl)propyl)-2-methyl-4-oxo-1,4-dihydropyridin-3-olate)-bis[(η⁵-pentamethylcyclopentadienyl)iridium(III)] Chloride

Molbank
A metallacyclic maltol-tethered organometallic Ir(III) half-sandwich complex was synthesized as an analog of the ruthenium anticancer complexes (RAPTA/RAED) to evaluate its in vitro antiproliferative activity against various human cancer cell lines.
Ilya A. Shutkov, Nikolai A. Melnichuk, Konstantin A. Lyssenko, Nataliya E. Borisova, Olga N. Kovaleva, Alexey A. Nazarov   +5 more
doaj   +1 more source

Antibacterial Polyketides from the Marine Alga-Derived Endophitic Streptomyces sundarbansensis: A Study on Hydroxypyrone Tautomerism

Marine Drugs, 2013
Polyketide 13 [=2-hydroxy-5-((6-hydroxy-4-oxo-4H-pyran-2-yl)methyl)-2- propylchroman-4-one] and three related known compounds 7, 9 and 11 were obtained and structurally characterized from Streptomyces sundarbansensis strain, an endophytic actinomycete ...
Ines Mancini, Andrea Defant, Ibtissem Djinni, Mouloud Kecha   +3 more
doaj   +1 more source

New 2-pyrone-based hydrazones: Synthesis, spectral characterisation, UV–visible study and evaluation of the antiradicalar activity

, 2016
The synthesis of new 2-pyrone-based hydrazones has been prepared by the coupling of 6-methyl-2H-furo[3,2-c]pyran-3,4-dione with diazonium salts, obtained by diazotization of aniline derivatives.
Malika Makhloufi-Chebli (3607037), Anissa Amar (1425829), Djamila Oukacha-Hikem (3607046), Artur M. S. Silva (1577557), Houria Bouherrou (3607043), Yahia Rachedi (3607034), Maamar Hamdi (3607040), Hacène Meghezzi (3607031)   +7 more
core   +1 more source