Results 81 to 90 of about 9,191 (227)

Bioactive Phytochemical Compounds in Medicago sativa L. (Alfalfa): A Systematic Review of Biological Properties and Therapeutic Relevance in Nutraceutical and Functional Food Implications

open access: yesFood Frontiers, Volume 7, Issue 2, March 2026.
ABSTRACT Medicago sativa L. (alfalfa) harbors a remarkably diverse reservoir of bioactive secondary metabolites. Flavonoids, isoflavones, and triterpenoid saponins dominate its bioactivity landscape, driving potent antioxidant, anti‐inflammatory, antimicrobial, estrogenic, hypolipidemic, and cytotoxic actions through redox modulation, membrane ...
Parham Joolaei Ahranjani   +3 more
wiley   +1 more source

General Method for the Preparation of Substituted 2-Amino-4H,5H-pyrano[4,3-b]pyran-5-ones and 2-Amino-4H-pyrano[3,2-c]pyridine-5-ones

open access: yesMolecules, 2000
Reaction of 4-hydroxy-6-methyl-2-pyrone (1a) as well as 4-hydroxy-6-methyl-2(1H)-pyridones (1b-d) with arylmethylene malononitriles or arylmethylene methyl cyanoacetates (2a-h) leads to the formation of the very stable 5,6-fused bicyclic 2-amino-4Hpyran ...
Dieter Heber   +2 more
doaj   +1 more source

Traditional Chinese Medicine as an Integrative Adjunct in Oncology Perioperative Practice: Analgesia, Immune Modulation, and Translational Challenges

open access: yesMedicine Bulletin, Volume 2, Issue 2, Page 184-204, March 2026.
ABSTRACT Traditional Chinese medicine (TCM), including herbal analgesic adjuvants and acupuncture‐based interventions, has gained increasing attention as an integrative strategy for perioperative pain management in oncology. Bioactive phytochemicals—such as terpenoids, flavonoids, alkaloids, and polyphenols—exert multimodal pharmacological effects ...
Yuqin Tang   +5 more
wiley   +1 more source

Regioselectivity in the Stille Coupling Reactions of 3,5-Dibromo-2-pyrone

open access: yes, 2016
The Stille couplings of 3,5-dibromo-2-pyrone normally take place regioselectively at C3, lower in electron density than C5, thus oxidative addition proceeds faster .
Hyung-Jin Kim (1427263)   +2 more
core   +1 more source

Protective Effects of Dimedone Pyrone on Podocytes in Rats with Diabetic Nephropathy

open access: yes, 2015
Purpose: To investigate the effect of dimedone pyrone (DP) on podocytes in rats with diabetic nephropathy (DN).Methods: The rats were randomly assigned into 5 experimental groups (n = 10), viz, non-diabetic  control with no treatment (ND/NT), diabetic ...
Luan, B, Sun, C
core   +1 more source

Novel biotransformation of a 2-pyrone to a substituted benzoic acid

open access: yes, 1985
It was found that Macrophoma commelinae (IFO 9570) had an ability to transform 5-acetyl-4-methoxy-6-methyl-2-pyrone (1) to 4-acetyl-3-methoxy-5-methylbenzoic acid (2). This biotransformation was investigated using 13C- and 14C-labeled compounds.
Suzuki, Harumi   +12 more
core   +2 more sources

Some Aspects of Pyrone Synthesis and Stability

open access: yes, 1967
Two methods for the preparation of [gamma]-pyronocoumarins have been performed; the ring closure of an o- hydroxy- [beta] - ketoacetylcoumarln and the Kostanecki-Robinson reaction of an o-hydroxy-acetylcoumarln.
Horinek, Ronald Louis
core   +1 more source

Density functional study of 4-pyrone and 2-pyrone

open access: yes, 2003
7-10Density functional (B3LYP) calculations using 6-31 G* have been made to estimate the bond lengths and angles for 4-pyrone and 2-pyrone. The predicted bond lengths and angles for 4-pyrone are in excellent agreement with experimental results ...
Ralhan, Sonia   +2 more
core  

Contribution of Pyrone-Type Structures to Carbon Basicity:  An ab Initio Study

open access: yes, 2016
The contribution to carbon basicity of pyrone-type structures is examined in this work by carrying out ab initio calculations on various cluster models. The different basic sites in a bicyclic pyrone structure are studied at the MP2/6-311+G(2d,2p)//MP2/6-
Enrique Fuente (2488285)   +3 more
core   +1 more source

Tandem Diels−Alder Cycloadditions of 2-Pyrone-5-acrylates for the Efficient Synthesis of Novel Tetracyclolactones

open access: yes, 2016
Readily prepared from the regioselective Pd-catalyzed coupling reactions of 3,5-dibromo-2-pyrone, 3-bromo-2-pyrone-5-carboxylates undergo tandem uninterrupted sequential Diels−Alder cycloaddition reactions with allyl vinyl ethers in a highly regio- and ...
Cheon-Gyu Cho (1725187)   +2 more
core   +2 more sources

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