Results 91 to 100 of about 68,672 (189)

Manipulation of cancer cell pyroptosis for therapeutic approaches: challenges and opportunities

Biomarker Research
Remarkable advances have been achieved following discoveries that gasdermins are the executioners of pyroptosis. The pyroptotic process consists a subcellular permeabilization phase and a cell lysis phase, the latter of which is irreversible.
Rui Miao, Xueying Wang, Jingyv Zhang, Qinyv Kang, Qing Liu, Xianglin Luo, Junwei Hou, Baorong Gao   +7 more
doaj   +1 more source

Apoptosis, Pyroptosis, and Necrosis: Mechanistic Description of Dead and Dying Eukaryotic Cells

, 2005
Susan L. Fink, Brad T. Cookson
openalex   +1 more source

Targeting epigenetic and post-translational modifications regulating pyroptosis for the treatment of inflammatory diseases

Pharmacological Research
Inflammatory diseases, including infectious diseases, diabetes-related diseases, arthritis-related diseases, neurological diseases, digestive diseases, and tumor, continue to threaten human health and impose a significant financial burden despite ...
Ri-Wen, Yu-Hang Yang, Tie-Ning Zhang, Chun-Feng Liu, Ni Yang   +4 more
doaj   +1 more source

Nucleic acid sensors and programmed cell death [PDF]

, 2020
Liverpool, Layal, Maelfait, Jonathan, Rehwinkel, Jan   +2 more
core   +2 more sources

Differential Regulation of Caspase-1 Activation, Pyroptosis, and Autophagy via Ipaf and ASC in Shigella-Infected Macrophages

, 2007
Toshihiko Suzuki, Luigi Franchi, Claudia Toma, Hiroshi Ashida, Michinaga Ogawa, Yuko Yoshikawa, Hitomi Mimuro, Naohiro Inohara, Chihiro Sasakawa, Gabriel Núñez   +9 more
openalex   +2 more sources

Mycobacterium tuberculosis Infection of Dendritic Cells Leads to Partially Caspase-1/11-Independent IL-1β and IL-18 Secretion but Not to Pyroptosis

, 2012
Hana Abdalla, Lalitha Srinivasan, Swati Shah, Katrin D. Mayer-Barber, Alan Sher, Fayyaz S. Sutterwala, Volker Briken   +6 more
openalex   +2 more sources

Erratum: Corrigendum: Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection [PDF]

, 2017
Gilad Doitsh, Nicole Galloway, Xin Geng, Zhiyuan Yang, Kathryn M. Monroe, Orlando Zepeda, Peter Hunt, Hiroyu Hatano, Stefanie Sowinski, Isa Muñoz-Arias, Warner C. Greene   +10 more
openalex   +1 more source

Burkholderia cenocepacia induces pyroptosis in macrophages.

, 2012
Roberto Rosales-Reyes, Daniel Aubert, Jennifer S. Tolman, Amal O. Amer, Miguel A. Valvano   +4 more
openalex   +1 more source

Caspase-11–mediated endothelial pyroptosis underlies endotoxemia-induced lung injury [PDF]

, 2017
Kwong Tai Cheng, Shiqin Xiong, Zhiming Ye, Zhigang Hong, Anke Di, Kit Man Tsang, Xiaopei Gao, Shejuan An, Manish Mittal, Stephen M. Vogel, Edward A. Miao, Jalees Rehman, Asrar B. Malik   +12 more
openalex   +1 more source

145 Pyroptosis and HIV-Induced CD4 T Cell Death

, 2012
Gilad Doitsh, Orlando Zepeda, Nicole Galloway, Isa Arias, Warner C. Greene   +4 more
openalex   +1 more source