Results 191 to 200 of about 70,546 (390)

Synthesis of Pyrrolidine Derivatives with Anti-cholinergic Properties. I : Synthesis of 1-Alkyl-3-(diphenylhydroxymethyl) pyrrolidines

, 1966
Fumiko Hamaguchi, S. OHKI
openalex   +2 more sources

A New synthesis of 4,5,6,7‐tetrahydrofuro[2,3‐c]pyridines and furo[2,3‐c]pyrrolidines [PDF]

, 1990
Anna Arnoldi, Giovanna Bregante, Patrizia Caldirola, Lucio Merlini, B. TAMBURINI   +4 more
openalex   +1 more source

Quinoline ATP Synthase Inhibitors with Activity Against Multidrug Resistant Acinetobacter baumannii and Pseudomonas aeruginosa

ChemMedChem, EarlyView.
Targeting ATP synthase in Gram‐negative pathogens. Presented is the first disclosure of quinoline‐derived antibiotics inhibiting multidrug resistant Acinetobacter baumannii ATP synthase and expansion of the structure activity relationship profile of Pseudomonas aeruginosa ATP synthase inhibitors.
Katie T. Ward, Alexander P. L. Williams, Angelina L. Dennison, Lena Aamir, Darien L. Allen, Britza Chavez‐Arellano, Toni A. Marchlewski, Mars L. Zappia, Amanda L. Wolfe, P. Ryan Steed   +9 more
wiley   +1 more source

Synthesis of Pyrrolidine Derivatives with Pharmacological Activity. V. : Synthesis of α-Cycloalkyl-α-phenyl-3-pyrrolidinemethanol Derivatives

, 1969
S. OHKI, Yunosuke Nagase, MOTOYO YOSHINO, TEIKO AZUMA, Fumiko Hamaguchi   +4 more
openalex   +2 more sources

Is Mycobacterial InhA a Suitable Target for Rational Drug Design?

ChemMedChem, EarlyView.
InhA is the target of isoniazid, a first‐line antituberculosis drug. Isoniazid is, in fact, a prodrug that needs to be activated. Researchers are trying to develop direct inhibitors of InhA. This includes the resolution of crystallographic structures. The Protein Data Bank contains over a hundred InhA structures.
Julien Rizet, Laurent Maveyraud, David Rengel, Valérie Guillet, Gabriel Publicola, Frédéric Rodriguez, Christian Lherbet, Lionel Mourey   +7 more
wiley   +1 more source

An Asymmetric Reduction of Prochiral Ketones with a Chiral Hydride Reagent Prepared from Lithium Aluminium Hydride and (S)-2-(2,6-Xylidinomethyl)pyrrolidine

, 1979
Teruaki Mukaiyama, Masatoshi Asami
openalex   +1 more source

Electron Transport Bilayer Design for Perovskite‐Based Tandem Solar Cells Using Thermal Evaporation

Chemistry–Methods, EarlyView.
We provide a comprehensive explanation of designing a bi‐layer electron transport layer with a fullerene layer using the evaporation method in inverted perovskite solar cells (PSCs) and perovskite‐based tandem solar cells (PTSCs). Furthermore, we provide candidate materials for a bi‐layer and suggest a fullerene/SnO2 bi‐layer configuration for high ...
Siwon Yun, Hyeji Han, Muhammad Adnan, Wonjong Lee, Min Kim, Jongchul Lim, Jinseck Kim   +6 more
wiley   +1 more source

4-(1-Methylamino)ethylidene-1,5-disubstituted pyrrolidine-2,3-diones: synthesis, anti-inflammatory effect and in silico approaches. [PDF]

Beilstein J Org Chem
Nguyen NT, Dai VV, Van Meervelt L, Thao DT, Thong NM.   +4 more
europepmc   +1 more source

Determination of Diketopiperazine Formation During the Solid‐Phase Synthesis of C‐Terminal Acid Peptides

Chemistry–Methods, EarlyView.
Diketopiperazine formation (DKP) is one of the most serious side reactions during peptide synthesis. An accurate method to determine the DKP formation in peptide synthesis on Wang resin is reported. Furthermore, the strategies to minimize this side reaction and side products lacking C‐terminal amino acids are described. Diketopiperazine formation (DKP)
Mani Kaushal, Ashish Kumar, Hassan Gamal, Sinenhlanhla N. Mthembu, Rotimi Sheyi, XiaoKang Kou, Beatriz G. de la Torre, Fernando Albericio   +7 more
wiley   +1 more source

Pyrrolidine synthesis via ring contraction of pyridines. [PDF]

Nat Commun
Ueno R, Hirano S, Takaya J.
europepmc   +1 more source