Results 171 to 180 of about 54,719 (255)

Human metabolism and pharmacological profiling of protonitazepyne and metonitazepyne, two highly potent nitazenes: prediction of main metabolite activity based on µ-opioid receptor docking simulations. [PDF]

Arch Toxicol
Berardinelli D, Taoussi O, Ovat DY, Pichini S, Pulver B, Auwärter V, Busardò FP, Basile G, Laudadio E, Carlier J.   +9 more
europepmc   +1 more source

Larger Substituents Enhance Stereospecificity in 1,1-Diazene Nitrogen Extrusion through Attenuation of Dynamic Mismatching. [PDF]

JACS Au
Wu RK, Zhang SQ, Hong X.
europepmc   +1 more source

Desymmetrization of <i>meso</i>-Pyrrolidines via Oxoammonium-Catalyzed Enantioselective Hydride Transfer. [PDF]

J Am Chem Soc
Rein J, Górski B, Keskin AM, Le MH, Lin S.   +4 more
europepmc   +1 more source

Intelligent design and synthesis of nucleobase and amino acid-based ligands to inhibit the JAK2 enzyme to treat rheumatoid arthritis. [PDF]

Amino Acids
Zarei A, Fatahi A.
europepmc   +1 more source

A novel pyrrolidine-chalcone derivative exhibits synergistic anti-cervical cancer activity by dual-targeting MDM2-p53 axis and ferroptosis pathway. [PDF]

Front Pharmacol
Xiamuxi H, Deng X, Ablise M, Yan T, Imam M, Wang Y, Zu M, Wumaier W.   +7 more
europepmc   +1 more source

Pyrrolidine dithiocarbamate accelerates early recovery of intestinal microvascular oxygenation in a reversible model of hemorrhagic shock in rats. [PDF]

J Transl Med
Hof S, Krüll L, Schmitt J, Neumann C, Marcus C, Kuebart A, Herminghaus A, Relja B, Vollmer C, Bauer I, Picker O, Truse R.   +11 more
europepmc   +1 more source

A Convenient Synthesis of CHF₂O-Containing Pyrrolidines and Related Compounds — Prospective Building Blocks for Drug Discovery

SynOpen
Kostiantyn Levchenko, Ivan Virstiuk, Daria Menshykova, Nazariy Pokhodylo   +3 more
doaj   +1 more source

Photochemical reduction of aryl chlorides, bromides, and iodides <i>via</i> ternary EDA complexes with guanidine bases. [PDF]

Chem Sci
Hannan RJ, Vondran AM, Cho S, Hanson KM, Tonnelé C, Casanova D, Bardeen CJ, Bahamonde A.   +7 more
europepmc   +1 more source

Retraction notice to "Pyrrolidine derivatives as α-amylase and α-glucosidase inhibitors: Design, synthesis, structure-activity relationship (SAR), docking studies and HSA binding" [Heliyon 10 (2024) e39444]. [PDF]

Heliyon
Bhat AA, Tandon N, Singh I.
europepmc   +1 more source

Automated parametrization of small molecules within the Martini 3 coarse-grained model guided by experimental log P values. [PDF]

Sci Rep
Kelidou M, Stroh KS, Risselada HJ.
europepmc   +1 more source