Synthetic Strategies for the Construction of Cyclobutane‐Fused Heterocycles
European Journal of Organic Chemistry, Volume 29, Issue 40, 27 October 2026.Cyclobutane‐fused heterocycles are important motifs commonly present in bioactive compounds, recognized for their rigid 3D structures that confer unique properties. However, synthesizing these compounds remains challenging. This review discusses current methods for their synthesis, such as photochemical, metal‐catalyzed, and Lewis acid‐mediated [2 + 2]
Michela Vargiu +2 more
wiley +1 more source
The Role of Pyrrolidine in Antibacterial Drug Discovery: Clinically Approved Antibiotics, Novel Derivatives, and Future Perspectives. [PDF]
Int J Mol SciRusu A +4 more
europepmc +1 more source
Pyrrolidine-Based Antifungal Agents Against <i>Candida</i> Species: A Systematic Review of Structure-Activity Relationships and Mechanistic Insights from Experimental Studies. [PDF]
Pharmaceuticals (Basel)Sinchan HG, Chaithra N, Umamaheshwari S.
europepmc +1 more source
Excess Gibbs energy. Pyrrolidine-cyclohexane system
, 1986 A data table and a correlation equation are presented for the excess free energy of the Pyrrolidine-cyclohexane system at 298.15 ...
CECCANTI, NORBERTO +2 more
core
A Pyridoxal 5'-Phosphate-Dependent Decarboxylative Mannich Reaction Initiates Construction of the Nonpeptidic Scaffold of Kaitocephalin. [PDF]
J Am Chem SocNoguchi T +4 more
europepmc +1 more source
Angewandte Chemie, Volume 138, Issue 43, 19 October 2026.The successful extension of the nickel‐catalyzed asymmetric coupling of polarized 1,3‐dienes with aldehydes to an intramolecular setting opens an efficient new entry into hydroxylated N‐heterocyclic compounds, most notably valuable tetrahydroisoquinolines.
Thilo Bender +3 more
wiley +2 more sources
Improved Library of Pyrrolidine-2,3-dione Monomers as Antimicrobial and Antibiofilm Agents against <i>Staphylococcus aureus</i>. [PDF]
ACS Med Chem LettKalliat SR, Valdes-Pena MA, Pierce JG.
europepmc +1 more source
Organocatalytic Asymmetric Formal Aza-[3 + 2] Cycloaddition via Domino Michael/Acetalization: Stereoselective Access to 3,4-<i>cis</i>-Disubstituted Pyrrolidines and Pot-Economical Total Syntheses of (-)-Kainic Acid and (-)-Domoic Acid. [PDF]
JACS AuHatano Y +3 more
europepmc +1 more source
Noses on the wing: the olfactory capacity of hawkmoth wings. [PDF]
J Exp BiolIsmaieel AR +3 more
europepmc +1 more source
Unifying Passive Air Sampling with Paper Spray Ionization Mass Spectrometry for the Detection of Third-Hand Cigarette Smoke. [PDF]
J Am Soc Mass SpectromKe BC, Abu Bakar NH, Urban PL.
europepmc +1 more source