Efficient Synthesis of Cyclopropane-Fused Heterocycles with Bromoethylsulfonium Salt [PDF]
Aggarwal +66 more
core +3 more sources
AlkaPlorer: A database‐driven explorer for natural alkaloids and derivatives
The alkaloid database AlkaPlorer integrates over 130,000 compounds across 12,250 species. By linking chemical structures with biological and evolutionary data, it reveals how these molecules evolve and function. This platform serves as a vital resource for AI‐driven discovery in plant metabolism and modern drug development. ABSTRACT Alkaloids, renowned
Jiahao Li +5 more
wiley +1 more source
Recent theoretical efforts to elucidate the origin of enantioselectivity in transition metal‐catalyzed propargylic substitution reactions are highlighted in this review. ABSTRACT In recent years, asymmetric catalytic propargylic substitution reactions have undergone remarkable development, enabling the construction of chiral carbon centers adjacent to ...
Ken Sakata, Yoshiaki Nishibayashi
wiley +1 more source
Synthesis of a Carbon‐Linked Acyldepsipeptide Derivative
The synthesis of a methylene‐linked acyldepsipeptide (ADEP) is reported. Success relied upon an improve method to generate a versatile vinyl glycine methyl ester synthon and a rationally optimized Grubb’s metathesis. NMR and in silico studies revealed an unusual trans–trans proline orientation for this new unnatural ADEP analog, advancing the ...
Katelyn G. Stevens-Davis +6 more
wiley +1 more source
Editorial: Recent advances in synthesizing and utilizing nitrogen-containing heterocycles
Takashi Ohshima +2 more
doaj +1 more source
A structural blueprint for antibacterial discovery: microwave- and ultrasound-assisted synthesis of pyrrolidine-fused quinoxalines as novel inhibitors of DNA gyrase and biofilm. [PDF]
Fayed EA +6 more
europepmc +1 more source
Photoredox-enabled late-stage functionalization of pyrrolidines in batch and flow: rapid access to benzothiazole hybrids as a new class of cholinesterase inhibitors. [PDF]
Filipović A +4 more
europepmc +1 more source
Synthesis of Tetrakis(amino)ethylene-Derived Organic Reductants via Thermal Decomposition of Tris(amino)methanes. [PDF]
Kim S +4 more
europepmc +1 more source
Comprehensive metabolic profiling of the new designer stimulant MDPiHP-in vitro and in vivo identification of potential biomarkers for detection in human samples. [PDF]
Balloni A +5 more
europepmc +1 more source
Kabbe condensation: a comprehensive review of spirochromanone synthesis and medicinal applications. [PDF]
Samandram R +6 more
europepmc +1 more source

