Dual‐functional polystyrene‐based polymers bearing 2,2′‐(pyridine‐2,6‐diyl)diphenol (PDP) moieties form photoexcitable alkyl borate complexes: (i) As recyclable radical sources, they enable Giese‐type additions with facile purification by reprecipitation and demonstrate proof‐of‐concept for polymer recovery (50% PDP regeneration).
Nami Jimba +9 more
wiley +1 more source
Design, Synthesis, X-Ray Crystallographic Characterization, Anticholinesterase and Antioxidant Evaluation, and Molecular Modeling of Novel Dispiroindene-Pyrrolidine Derivatives as Multifunctional Anti-Alzheimer Agents. [PDF]
Alsfouk AA +7 more
europepmc +1 more source
Counterion Effects in Decatungstate Photocatalysis
Decatungstate photocatalysis is often discussed from an anion‐centered perspective, treating the counterion as a passive charge‐balancing species. This review highlights that counterion identity can instead profoundly influence catalyst solubility, ion pairing, aggregation, stability, substrate accessibility, and catalytic performance.
Florence Babawale +2 more
wiley +1 more source
Modifying the conformational ensemble of “molten‐globule” protein by the site‐specific incorporation of stereoisomeric 4‐fluoroproline residues modulated its binding affinity and aggregation behavior. 19F NMR spectroscopy enabled the detection of key interactions responsible for structural and dynamic changes. ABSTRACT Recently, the application of deep
Abir Ben Bouzayene +5 more
wiley +2 more sources
Spirooxindole Derivatives as Emerging Scaffolds in Drug Discovery: Synthetic Strategies, Structure-Activity Relationship, and Biological Activities. [PDF]
Kalita RC, Bezbaruah S, Patle D.
europepmc +1 more source
Comparative study of armchair and zigzag graphene quantum dots as HIV-1 protease inhibitors. [PDF]
Ibrahim A, Elhaes H, Ibrahim MA.
europepmc +1 more source
Recent Advances in Intramolecular C─N Bond Formation for Pyrrolidine Synthesis. [PDF]
Kroņkalne R, Turks M.
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Visible‐Light Cobalt‐Catalyzed Synthesis of Aroyl Amides From Arylazo Sulfones
Blue Light and Cobalt Catalysis for Synthesis! A versatile strategy that combines photoactive arylazo sulfones as substrates and Co2(CO)8 as a catalyst for the preparation of aromatic amides is presented herein. A versatile strategy leveraging the peculiar reactivity of arylazo sulfones as substrates bearing dyedauxiliary groups in arylation processes,
Komal Jaiswal +4 more
wiley +1 more source
Facile Synthesis of Indole-, Pyrazole-, and Indazole-Pyrrolidine Hybrids as Novel Chiral Heterocyclic Building Blocks. [PDF]
Jankauskas R +8 more
europepmc +1 more source
Multitarget Drug Design for Cardiovascular Disease: Bridging Chemistry and Medicine
Many pathophysiological pathways associated with cardiovascular diseases involve multiple drug targets. This article reviews recent advances in the development of pharmacological compounds capable of simultaneously modulating multiple mechanisms. Multitarget drugs offer a promising therapeutic approach for complex cardiovascular disorders, including ...
Gyuzel Y. Mitronova +3 more
wiley +1 more source

