Results 351 to 360 of about 70,546 (390)

Asymmetric Construction of Spirocyclic Pyrrolidine-thia(oxa)zolidinediones via N,O-Ligand/Cu(I) Catalyzed 1,3-Dipolar Cycloaddition of Azomethine Ylides with 5-Alkylidene Thia(oxa)zolidine-2,4-diones.

Organic Letters, 2015
A highly efficient asymmetric 1,3-dipolar cycloaddition of azomethine ylides to 5-alkylidene thia(oxa)zolidine-2,4-diones catalyzed by a chiral N,O-ligand/Cu(CH3CN)4BF4 system is reported, affording structurally novel spirocyclic pyrrolidine-thia(oxa ...
Wulin Yang, Fei-Fei Tang, F. He, Chun-Yan Li, Xingxin Yu, W. Deng   +5 more
semanticscholar   +1 more source

Synthesis of pyrrolidine-2–14C

Journal of Pharmaceutical Sciences, 1967
The preparation of pyrrolidine-2– 14 C picrate in satisfactory yields from potassium cyanide- 14 C and from barium carbonate- 14 C is reported. Reaction of pyrrolidine picrate with lithium hydroxide followed by distillation separated the free base.
Wayne V. Kessler, John E. Christian, John M. Walts   +2 more
openaire   +3 more sources

A strategic approach to the synthesis of functionalized spirooxindole pyrrolidine derivatives: in vitro antibacterial, antifungal, antimalarial and antitubercular studies

, 2015
A series of spiro[pyrrolidin-2,3′-oxindoles] has been synthesized by exo-selective 1,3-dipolar cycloaddition reaction of a stabilized azomethine ylide, generated in situ by thermal [1,5]-prototropy, across various (E)-3-arylidene-1-phenyl-pyrrolidine-2,5-
S. Haddad, Sarra Boudriga, T. N. Akhaja, J. Raval, F. Porzio, A. Soldera, Moheddine Askri, M. Knorr, Yoann Rousselin, M. Kubicki, D. Rajani   +10 more
semanticscholar   +1 more source

Synthesis of polyhydroxylated piperidine and pyrrolidine peptidomimetics via one-pot sequential lactam reduction/Joullié-Ugi reaction.

Journal of Organic Chemistry, 2015
A direct approach to the synthesis of polyhydroxylated piperidine and pyrrolidine peptidomimetics is described. The presented strategy is based on one-pot reduction of sugar-derived lactams with Schwartz's reagent followed by a multicomponent Ugi-Joullié
P. Szcześniak, E. Maziarz, S. Stecko, B. Furman   +3 more
semanticscholar   +1 more source

1,3‐Dipolar Cycloaddition of Benzofuranone Derivatives and Azomethine Ylides Promoted by Simple Functional Ionic Liquids: Direct Access to Highly Substituted Pyrrolidine and Spirocyclic Benzofuranone

, 2016
We have successfully established an efficient catalytic system, which was effective for construction of both spiro[pyrrolidine-benzofuran-3-one] and spiro[pyrrolidine-benzofuran-2-one] compounds.
Chuan-Bao Zhang, Pei‐Hao Dou, Jun Zhang, Q. Wei, Yan-Bo Wang, Jun-Yan Zhu, Ji-Ya Fu, T. Ding   +7 more
semanticscholar   +1 more source

Synthesis of functionalized β-lactams and pyrrolidine-2,5-diones through a metal-free sequential Ugi-4CR/cyclization reaction.

Journal of Organic Chemistry, 2014
An efficient approach for the synthesis of functionalized β-lactams and pyrrolidine-2,5-diones was achieved through a sequential Ugi-4CR/cyclization reaction.
Elmira Ghabraie, S. Balalaie, Saber Mehrparvar, F. Rominger   +3 more
semanticscholar   +1 more source

Combinatorial synthesis of functionalized spirooxindole-pyrrolidine/pyrrolizidine/pyrrolothiazole derivatives via three-component 1,3-dipolar cycloaddition reactions.

ACS Combinatorial Science, 2014
A series of diverse polycyclic heterocycles containing spirooxindole, pyridine/thiophene, and pyrrolidine/pyrrolizidine/pyrrolothiazole rings have been synthesized through the 1,3-dipolar cycloaddition of azomethine ylides generated in situ by the ...
J. Li, Jing Wang, Zhou Xu, Songlei Zhu
semanticscholar   +1 more source

Dual platinum and pyrrolidine catalysis in the direct alkylation of allylic alcohols: selective synthesis of monoallylation products.

Angewandte Chemie, 2014
A dual platinum- and pyrrolidine-catalyzed direct allylic alkylation of allylic alcohols with various active methylene compounds to produce products with high monoallylation selectivity was developed. The use of pyrrolidine and acetic acid was essential,
Ryozo Shibuya, Lu Lin, Y. Nakahara, K. Mashima, T. Ohshima   +4 more
semanticscholar   +1 more source

Arylthiolation of Arylamine Derivatives with (Arylthio)‐ pyrrolidine‐2,5‐diones

, 2015
A simple and efficient method for arylthiolation of arylamines has been developed. The protocol uses (arylthio)pyrrolidine-2,5-diones as the arylthiolating reagents, acetonitrile as the solvent, and no catalyst and additive are required, which avoids ...
Hua Tian, Haijun Yang, Changjin Zhu, H. Fu   +3 more
semanticscholar   +1 more source

Isolation and biosynthesis of preussin B, a pyrrolidine alkaloid from Simplicillium lanosoniveum.

Journal of Natural Products, 2014
A new pyrrolidine alkaloid, preussin B (1), was isolated from the culture extract of the fungus Simplicillium lanosoniveum TAMA 173 along with the known congener preussin (2). The structure and absolute configuration of 1 were determined by spectroscopic
Takao Fukuda, Y. Sudoh, Y. Tsuchiya, T. Okuda, Y. Igarashi   +4 more
semanticscholar   +1 more source