Results 101 to 110 of about 36,836 (288)
Molecules, 2016 Drug-like spirocyclic scaffolds have been prepared by fusing fully functionalized pyrrolidine with oxindoles in an approach based on 1,3-dipolar cycloaddition.
Wen Ren +5 more
doaj +1 more source
Influence of EDTA Coverage Density on Optical Fiber Sensor for Heavy Metal Ion Detection
Nano Select, EarlyView.This study investigates the influence of chelating agent coverage on the performance of optical fiber sensors for heavy metal ion detection. Ethylenediaminetetraacetic acid (EDTA) was employed to functionalize single‐mode 28 optical fibers (SMF‐28), and the influence of surface coverage uniformity on zinc ion sensing performance was investigated ...
Zhejun Xu +5 more
wiley +1 more source
A Self‐Healing Conductive PVP/SUM Hydrogel for Real‐Time Human Motion Detection
Nano Select, EarlyView.The PVP/SUM hydrogel exhibits self‐healing, conductivity, and strong mechanical performance due to H‐bonds and dipole–dipole interactions. It elongates up to 330% and shows fracture strength between 0.9 and 1.5 MPa under varying strain rates. With a conductivity of 3.28 × 10−5 S/cm, it responds rapidly to human motion, enabling real‐time monitoring for
Vinnakoti Meghana, Illa Ramakanth
wiley +1 more source
The Journal of Organic Chemistry, 2002 We report the enantiospecific synthesis of the sterically congested all-cis 2,3,4,5-substituted pyrrolidines 4, 5, and 6, from either D- or L-serine. Hemiaminal intermediate 13 is converted to the fully substituted pyrrolidine 15 by way of a tandem Wittig-Michael reaction.
Verma, S.K. +4 more
openaire +4 more sources
ChemistryOpen, EarlyView.In organic synthesis, deep eutectic solvents (DES) have demonstrated their ability to be used as reaction media for the development of reactions in line with green chemistry principles. This review presents an overview of microwave‐assisted organic synthesis in DES, highlighting the diversity of uses for these solvents, their role in mechanisms, the ...
Pierre‐Olivier Delaye +2 more
wiley +1 more source
Asymmetric transformations involving 1,2-diarbonyl compounds as pronucleophiles
, 2012 International audienceThis article concentrates on the versatile nucleophilic reactivity of 1,2-dicarbonyl compounds in various asymmetric transformations. Although underexploited in comparison to their 1,3-dicarbonyl homologues, the presence of adjacent
Bonne, Damien +2 more
core +3 more sources
X=Y–ZH compounds as potential 1,3-dipoles. Part 64: Synthesis of highly substituted conformationally restricted and spiro nitropyrrolidines via Ag(I) catalysed azomethine ylide cycloadditions [PDF]
, 2008 1,3-Dipolar reactions of imines of both acyclic and cyclic α-amino esters with a range of nitroolefins using a combination of AgOAc or Ag2O with NEt3 are described.
Albert +51 more
core +1 more source
ChemistryOpen, EarlyView.Targeting a nucleotide‐sensitive groove on Hsp70 that binds the Bim BH3 helix, we integrate structures, biophysics, and SAR from peptides, fragments, and phenalene‐dicarbonitrile “wedges.” These disrupt the Hsp70–Bim complex with sub‐µM cellular engagement and in vivo activity while sparing Hsp90/mortalin.
Emadeldin M. Kamel +5 more
wiley +1 more source
Synthetic applications of chiral unsaturated epoxy alcohols prepared by sharpless asymmetric epoxidation [PDF]
, 2010 An overview of the synthesis and applications of chiral 2,3-epoxy alcohols containing unsaturated chains is presented. One of the fundamental synthetic routes to these compounds is Sharpless asymmetric epoxidation, which is reliable, highly ...
Moreno, María, Riera i Escalé, Antoni
core +2 more sources